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Source: Neurology
Condition: Epilepsy

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Total 139 results found since Jan 2013.

PiB-PET detects transthyretin-related cerebral amyloid angiopathy
Transthyretin (TTR) is an amyloidogenic protein synthesized primarily (>95%) by the liver and, to a lesser extent, by the choroid plexuses and retinal pigment epithelium. Hereditary TTR amyloidosis (ATTR) is a multisystem disorder that may manifest with 3 main clinical phenotypes: familial amyloid polyneuropathy (FAP), familial amyloid cardiomyopathy, and familial leptomeningeal amyloidosis.1 TTR-FAP is the most common presentation. More than 130 autosomal dominant mutations cause ATTR, with the Val30Met mutation being the most frequent variant worldwide: prevalence of up to 1:1,000 in endemic regions of Portugal, Swede...
Source: Neurology - August 21, 2016 Category: Neurology Authors: Cavallaro, T., Klunk, W. Tags: PET, Peripheral neuropathy, All Cerebrovascular disease/Stroke, All Genetics EDITORIALS Source Type: research

Excess mortality and hospitalized morbidity in newly treated epilepsy patients
Conclusions: Newly treated epilepsy patients bear excess mortality and hospitalization risks. They have higher risk of developing stroke, ischemic heart disease, and cancer. Treatment with EIAEDs was associated with increased overall morbidity.
Source: Neurology - August 14, 2016 Category: Neurology Authors: Chen, Z., Liew, D., Kwan, P. Tags: All Epilepsy/Seizures, Antiepileptic drugs ARTICLE Source Type: research

Neonatal seizures triple the risk of a remote seizure after perinatal ischemic stroke
Conclusions: Remote seizures and epilepsy, including medically refractory epilepsy, are common after perinatal stroke. Neonatal seizures are associated with nearly 3-fold increased remote seizure risk.
Source: Neurology - June 5, 2016 Category: Neurology Authors: Fox, C. K., Glass, H. C., Sidney, S., Smith, S. E., Fullerton, H. J. Tags: Childhood stroke, Prognosis, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke, Risk factors in epidemiology, All Epilepsy/Seizures ARTICLE Source Type: research

Simulation of Neurological Emergencies for Milestones-Based Learning and Assessment (P2.357)
CONCLUSIONS: Simulations of neurological emergencies can increase resident comfort in several aspects of care and can be used to reliably assess resident competence based on the Neurology Milestones.Disclosure: Dr. Loomis has nothing to disclose. Dr. Robeson has nothing to disclose. Dr. DiCapua has received personal compensation for activities as a consultant. Dr. Dodge has nothing to disclose. Dr. Evans has nothing to disclose. Dr. Moadel has nothing to disclose. Dr. Cruz has nothing to disclose. Dr. Moeller has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Loomis, C., Robeson, K., DiCapua, D., Dodge, K., Evans, L., Moadel, T., Cruz, L., Moeller, J. Tags: Education Research: Graduate Medical Education Source Type: research

Teaching a Neurology Continuing Medical Education Course to Ghanaian Physician Assistants (P1.281)
Conclusions: The provision of education in the diagnosis and treatment of neurological conditions to primary care providers is one intervention that can address the limited supply of neurologists in lower income countries. This study suggests that a continuing medical education course can increase participant self-confidence in major topics in neurology and that the most valuable contribution of an educational intervention could be instruction in the neurological exam.Disclosure: Dr. O'Donnell has nothing to disclose. Dr. Renner has nothing to disclose. Dr. Hannon has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: O'Donnell, S., Renner, D., Hannon, P. Tags: Global Health: Infectious Disease, Capacity Building, and Other Source Type: research

Non-Medical Explanations of Neurological Illnesses among Healthcare Professionals (P1.282)
Conclusion: Supernatural explanations of neurological symptoms are indeed prevalent among healthcare professionals. This requires further study as to how this affects patient careDisclosure: Dr. Khayat has nothing to disclose. Dr. Milyani has nothing to disclose. Dr. Tayeb has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Khayat, A., Milyani, H., Tayeb, H. Tags: Global Health: Infectious Disease, Capacity Building, and Other Source Type: research

Development of Neurology-Specific Scenarios for Assessing Quality Improvement Knowledge Application During Residency Using the Revised Quality Improvement Knowledge Application Tool (QIKAT-R) (P2.377)
Conclusions: The QIKAT-R tool, when used with neurology-specific scenarios, can provide valid assessments of QI knowledge application among neurology residents, and serve as a novel way to introduce residents to the AAN Quality Measures and IOM Aims for high-quality healthcare.Disclosure: Dr. Kassardjian has nothing to disclose. Dr. Leep has received royalty payments from American Association of Neuromuscular and Electrodiagnostic Medicine.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kassardjian, C., Leep Hunderfund, A. Tags: Research Methodology and Education: Patient Safety and Quality Source Type: research

Temporal Trends of Post-Stroke Early Seizures or Epilepsy During Acute Ischemic Stroke Hospitalizations and Its Impact on Clinical Outcomes (P1.062)
CONCLUSIONS: AIS is associated with an increased risk of subsequent seizures and epilepsy. If this occurs early during the same hospitalization of stroke then it carries high morbidity, mortality and higher odds of discharge to specialized care as compared to stroke without occurrence of concomitant seizures.Disclosure: Dr. Patel has nothing to disclose. Dr. Jani has nothing to disclose. Dr. Shah has nothing to disclose. Dr. Schulte has nothing to disclose. Dr. Lunagariya has nothing to disclose. Dr. Onteddu has nothing to disclose. Dr. Mehta has nothing to disclose. Dr. Burghardt has nothing to disclose. Dr. Kassab has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Patel, A., Jani, V., Shah, H., Schulte, A., Lunagariya, A., Onteddu, S., Mehta, S., Burghardt, T., Kassab, M. Tags: Epilepsy/Clinical Neurophysiology: Health Services and Outcomes Research Source Type: research

A Survey of Functional Movement Disorders at the National Institutes of Health (P1.073)
OBJECTIVE: To better characterize the clinical presentation of functional movement disorders. BACKGROUND: Functional (psychogenic) movement disorders are receiving greater attention as valid and treatable neurologic disorders. Unfortunately, the often long list of complaints with variable presentations may hamper timely diagnosis and treatment. METHODS: We reviewed 113 charts retrospectively of patients presenting to the National Institutes of Health. Patients were referred from 44 states and the District of Columbia, with the majority presenting from the local Washington D.C. metropolitan area. Most patients were diagnose...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Ahmad, O., Maurer, C., Villegas, M. A. F., Lungu, C., Hallett, M. Tags: Movement Disorders: Miscellaneous Source Type: research

Nursing Home Residents with Seizure Disorders/Epilepsy: Prevalence, Characteristics, and Treatment Patterns (P1.080)
Conclusions: NHRs with seizure disorder/epilepsy have substantial physical and cognitive impairment. Nearly half were prescribed combination AED therapy, and >20[percnt] took 蠅3 different AEDs, suggesting refractory epilepsy. Additional research is needed to assess treatment outcomes and further define optimal care in this population.Disclosure: Dr. Zarowitz has nothing to disclose. Dr. Allen has nothing to disclose. Dr. OShea has nothing to disclose. Dr. Wang has nothing to disclose. Dr. Semenchuk has nothing to disclose. Dr. Barghout has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zarowitz, B., Allen, C., OShea, T., Wang, Z., Semenchuk, M., Barghout, V. Tags: Epilepsy/Clinical Neurophysiology: Geriatric Epilepsy, Epidemiology, and Health Services Source Type: research

Assessment of Status Epilepticus in Elderly Population: Geriatric Onset vs. Non-Geriatric Onset Epilepsy (P1.084)
Conclusion:SE is more common in GOE, however we did not show non-convulsive SE to occur more frequently. The underlying etiology did differentiate the GOE from the NGOE group with intracerebral hemorrhage and ischemic stroke more frequent. The presence of certain triggers increase the likelihood of SE in GOE patients, emphasizing the need for higher suspicion of SE in this vulnerable group in order to prevent morbidity and mortality.Disclosure: Dr. O'Dwyer has nothing to disclose. Dr. Rajebi has nothing to disclose. Dr. Fahimi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: O'Dwyer, R., Rajebi, H., Fahimi, G. Tags: Epilepsy/Clinical Neurophysiology: Geriatric Epilepsy, Epidemiology, and Health Services Source Type: research

Temporal and Racial Trends in Post-Stroke Dementia in the "Stroke Buckle" of the United States (P1.099)
CONCLUSIONS: Over the last decade, incidence of PSD significantly increased in South Carolina. Black stroke patients had higher overall rates of PSD than whites, but this difference was largely driven by a comparatively greater burden of Non-AD dementia. Since Non-AD dementia is predominantly composed of vascular dementia, better vascular risk factor control may help bridge this racial disparity.Disclosure: Dr. Boan has nothing to disclose. Dr. Lackland has nothing to disclose. Dr. Feng has nothing to disclose. Dr. Voeks has nothing to disclose. Dr. Adams has received personal compensation for activities with Reach Call In...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Boan, A., Lackland, D., Feng, W., Voeks, J., Adams, R., Bachman, D., Ovbiagele, B. Tags: Neuroepidemiology: Aging and Dementia, Epilepsy, and Education Source Type: research

The Changing Landscape of Ethical Issues in Neurology Practice and Research (P1.365)
Conclusions: As technological advancements provide neurologists with more diagnostic and treatment options ethical considerations need to be reassessed in order to ensure adherence to medical and neurological professional codes of conduct. Many of these technological advancements have provided neurologists with tools and treatment options which although appear promising, are far from universally understood or accepted. New concerns regarding Brain death, neuro-enhancement, and TBI have emerged and merit further study.Disclosure: Dr. Bergquist has nothing to disclose. Dr. Theriault has nothing to disclose. Dr. Etienne has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Bergquist, P., Theriault, M., Etienne, M. Tags: Ethics and Policy Source Type: research

Neuroimaging Markers of Cognitive Outcome in Children with Perinatal Stroke (I2.002)
Conclusions: As seen in other studies, prognosis of cognitive outcome is difficult and there was no correlation between site of lesion and areas of intellectual deficit. However, there was some indication that loss of more cortical volume, or involvement of the DLPF cortex may be risk factors for intellectual impairment in childhood.Disclosure: Dr. Murias has nothing to disclose. Dr. Kirton has nothing to disclose. Dr. Tariq has nothing to disclose. Dr. Moir has nothing to disclose. Dr. Iaria has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Murias, K., Kirton, A., Tariq, S., Moir, A., Iaria, G. Tags: Stroke in the Elderly and Young: Challenges for the Next Decade Data Blitz Presentations Source Type: research

Neurologic Presentation of K2: A City Hospital Experience (P2.258)
Conclusions: There are many common reported toxicities with synthetic cannabinoid use. We report our neurologic experience at Harlem Hospital. The incidence of seizures was high implicating K2 as either a provoking factor of patients with underlying epilepsy or one that could lower the seizure threshold sufficiently to provoke seizure in patients with no prior history.Disclosure: Dr. Kleiman has nothing to disclose. Dr. Ravichandran has nothing to disclose. Dr. Macaluso has nothing to disclose. Dr. Brust has received personal compensation in an editorial capacity for Current Neurology and Neuroscience Reports, and The Neurologist.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kleiman, A., Ravichandran, A., Macaluso, C., Brust, J. Tags: General Neurology Source Type: research