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Source: Europace
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Total 183 results found since Jan 2013.
142 Do atrial high rate episodes & lt;6 minutes in duration in pacemaker patients increase stroke risk?
Introduction: Atrial fibrillation (AF) is a well-known risk factor for stroke. Recently, episodes as short as 6 minutes in duration have been linked with an increased risk of ischaemic stroke in pacemaker (PPM) patients (Healeyet al., 2012).
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
14 Primary care based opportunistic screening for atrial fibrillation increases detection rates
Introduction: Atrial fibrillation (AF) remains a leading cause of ischaemic stroke despite the availability of effective medications. A major hurdle for effective management is often the asymptomatic nature of AF. Improved diagnosis and management has potential significant benefits for individual patients and economically for our health service due to the expensive nature of stroke care. In conjunction with Hounslow Cardiovascular Clinical Network (a collaborative of primary, secondary, community care and patient groups) and the NIHR CLAHRC Northwest London, we set out to improve the detection, quality of care and outcomes...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
15 Early prolonged ambulatory cardiac monitoring in stroke (EPACS) – an open-label randomised controlled trial
Introduction: Cardioembolism in paroxysmal atrial fibrillation (PAF) is a preventable cause of transient ischaemic attack (TIA) or ischaemic stroke, however, due its transient nature, a short-duration Holter monitor may miss a significant proportion of events. There are current limitations in ECG recording beyond 3-7 days. While implantable loop recorders require a minor surgical procedure, event-triggered loop recorders are cumbersome to use. We investigated whether there was a role for early prolonged cardiac monitoring using a novel patient-friendly cardiac monitoring system on patients presenting early after a stroke or TIA.
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
17 Atrial arrhythmia detection by implantable loop recorder in patients with and without previous stroke; implications for investigating patients with unexplained ischaemic stroke
Background/Introduction: Among patients with unexplained ischaemic stroke, prolonged cardiac rhythm monitoring with an Implantable Loop Recorder (ILR) has been found to uncover a high incidence of Atrial Fibrillation (AF). However, the incidence of AF detected by ILR in the general population is not known, making it possible that AF detected among stroke patients simply reflects background “noise.” It is also unclear what burden of AF is required to increase stroke risk and whether short bursts of AF are truly pathologic or simply normal phenomena, detected in the general population.
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
Age and sex differences in atrial fibrosis among patients with atrial fibrillation
ConclusionsAdvancing age and female sex are associated with a higher burden of atrial fibrosis in patients with AF. Women with a prior history of stroke also have higher fibrosis compared with both women and men without history of stroke. Advanced fibrosis may explain the female and age association with stroke in AF.
Source: Europace - August 9, 2017 Category: Cardiology Source Type: research
The influence of progression of atrial fibrillation on quality of life: a report from the Euro Heart Survey
ConclusionAF progression is associated with a decrease in HRQoL. However, multivariate analysis revealed that AF progression itself does not have a negative effect on HRQoL, but that this effect can be attributed to a minor effect of the associated symptoms and a major effect of associated adverse events.
Source: Europace - July 19, 2017 Category: Cardiology Source Type: research
Epicardial left atrial appendage AtriClip occlusion reduces the incidence of stroke in patients with atrial fibrillation undergoing cardiac surgery
ConclusionThe long-term results from our first-in-man prospective human trial plus our institutional registry of epicardial LAA occlusion with the AtriClip in patients with AF undergoing cardiac surgery demonstrate the safety and durability of the procedure. In addition, our data are suggestive for the potential efficacy of LAA occlusion in reducing the incidence of stroke. If validated in future large randomized trials, routine LAA occlusion in patients undergoing cardiac surgery (with contraindications to treatment with oral anticoagulants) may represent a reasonable adjunct procedure to reduce the risk of future stroke....
Source: Europace - July 18, 2017 Category: Cardiology Source Type: research
Non-vitamin K antagonist oral anticoagulants in atrial fibrillation patients undergoing elective cardioversion
ConclusionThrombotic and bleeding complications related to NOACs were uncommon (<0.5%) in real life AF patients undergoing elective cardioversion.
Source: Europace - July 10, 2017 Category: Cardiology Source Type: research
Combining Watchman left atrial appendage closure and catheter ablation for atrial fibrillation: multicentre registry results of feasibility and safety during implant and 30 days follow-up
ConclusionThe outcomes from these international, multicentre registries support the feasibility and safety of performing combined procedures of ablation and Watchman LAAC for patients with non-valvular AF and high stroke risk. Further data are needed on long-term outcomes for the hybrid technique on all-cause stroke and mortality.
Source: Europace - July 3, 2017 Category: Cardiology Source Type: research
Symptomatic atrial fibrillation and risk of cardiovascular events: data from the Euro Heart Survey
ConclusionPersistence or development of symptoms after medical treatment are associated with an increased risk of CV events during a 1-year follow-up. Type of AF, along with hypothyroidism, COPD and chronic heart failure are significantly associated with symptoms persistence despite medical treatment.
Source: Europace - June 30, 2017 Category: Cardiology Source Type: research
Shifting to a non-vitamin K antagonist oral anticoagulation agent from vitamin K antagonist in atrial fibrillation
ConclusionIn a contemporary setting among VKA-experienced NVAF patients; VKA is still prevalent although about 30% by December 2015 had shifted to a NOAC.
Source: Europace - June 28, 2017 Category: Cardiology Source Type: research
Hypertension and cardiac arrhythmias: a consensus document from the European Heart Rhythm Association (EHRA) and ESC Council on Hypertension, endorsed by the Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS) and Sociedad Latinoamericana de Estimulaci ón Cardíaca y Electrofisiología (SOLEACE)
AbstractHypertension is a common cardiovascular risk factor leading to heart failure (HF), coronary artery disease, stroke, peripheral artery disease and chronic renal insufficiency. Hypertensive heart disease can manifest as many cardiac arrhythmias, most commonly being atrial fibrillation (AF). Both supraventricular and ventricular arrhythmias may occur in hypertensive patients, especially in those with left ventricular hypertrophy (LVH) or HF. Also, some of the antihypertensive drugs commonly used to reduce blood pressure, such as thiazide diuretics, may result in electrolyte abnormalities (e.g. hypokalaemia, hypomagnes...
Source: Europace - June 17, 2017 Category: Cardiology Source Type: research
Dabigatran vs. warfarin in relation to the presence of left ventricular hypertrophy in patients with atrial fibrillation — the Randomized Evaluation of Long-term anticoagulation therapY (RE-LY) study
ConclusionsLVH was associated with a lower antithrombotic efficacy of warfarin, but not of dabigatran, in patients with AF. Consequently, the relative benefit of the lower dose of dabigatran compared to warfarin was enhanced in patients with LVH. The higher dose of dabigatran was superior to warfarin regardless of LVH status.Clinical trial registrationhttp:www.clinicaltrials.gov. Unique identifier: NCT00262600.
Source: Europace - May 17, 2017 Category: Cardiology Source Type: research
Long-term clinical impact of permanent cardiac pacing after transcatheter aortic valve implantation with the CoreValve prosthesis: a single center experience
ConclusionPatients requiring a PPM after TAVI did not have an increase in mortality, or an increase in the likelihood of developing a stroke at a long-term follow-up. However, this subgroup of patients showed an increase in rehospitalization due to HF at medium- and long-term follow-up.
Source: Europace - May 4, 2017 Category: Cardiology Source Type: research
Non-vitamin K-dependent oral anticoagulants have a positive impact on ischaemic stroke severity in patients with atrial fibrillation
ConclusionNOAC intake before stroke did reduce the probability of severe stroke on hospital admission and poor functional outcome at hospital discharge as similarly demonstrated for phenprocoumon patients with an INR ≥ 2 on admission.
Source: Europace - April 27, 2017 Category: Cardiology Source Type: research
