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Source: Europace
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Total 183 results found since Jan 2013.
Challenges in comparing the non-vitamin K antagonist oral anticoagulants for atrial fibrillation-related stroke prevention
AbstractThe aim of this review is to provide context for meta-analyses interpreting data from phase III stroke prevention studies of non-vitamin K antagonist oral anticoagulants (NOACs) in patients with non-valvular atrial fibrillation (NVAF). Differences between the four phase III NOAC stroke prevention studies in patients with NVAF (ROCKET AF, ARISTOTLE, RE-LY, and ENGAGE AF), their potential impact on outcomes, and inter-study differences were evaluated, as well as the potential role of real-world evidence in evaluating NOACs in this setting. Study design differences included blinding strategy, dose-reduction options, a...
Source: Europace - October 13, 2017 Category: Cardiology Source Type: research
Frailty syndrome: an emerging clinical problem in the everyday management of clinical arrhythmias. The results of the European Heart Rhythm Association survey
In conclusion, the complex clinical condition in frail patients presenting with arrhythmias warrants an integrated multidisciplinary approach both for the management of rhythm disturbances and for the decision on using CIEDs.
Source: Europace - October 10, 2017 Category: Cardiology Source Type: research
69 Identifying opportunities to prevent AF-related stroke through better access to NHS primary and secondary care data
Introduction: Public Health England (PHE) has set a target to reduce the incidence of avoidable strokes in patients with atrial fibrillation (AF) by 5,000 nationally over the next 5 years. Aligned with this goal, Greater Manchester (GM) Academic Health Sciences Network (AHSN) launched an online data visualisation platform in 2015 that provides a unique opportunity to view and compare multiple primary and secondary care datasets across the AF care pathway to help prevent avoidable AF-related strokes. It is endorsed by PHE and has been adopted by multiple AHSNs across the country.
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
82 Long term outcome following left atrial appendage occlusion: real world experience from a single centre prospective registry
We present the long-term survival outcome of LAAO patients from a single centre prospective registry.
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
87 Clinical evaluation of the ‘pulse smart rhythm analyst’: a novel software algorithm and pulse oximeter combination for mass screening of atrial fibrillation
Introduction: Atrial fibrillation (AF) is the most common cardiac arrhythmia, with a prevalence of 1-2% in the general population. Screening for and anticoagulating patients with asymptomatic AF may prove an additional opportunity to prevent stroke, heart failure and premature death in the general population. However, screening programmes to detect asymptomatic AF have not been undertaken; in part due to the prohibitive logistics and cost effectiveness of 12-lead ECGs and clinicians able to interpret them. We designed and evaluated a practical and scalable technology to address this.
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
88 One-year outcomes of triple therapy and adherence with ESC guidelines in patients with AF undergoing PCI in a teaching hospital
Background/Introduction: Oral anticoagulation is the corner-stone for stroke prevention in Atrial Fibrillation (AF).Following Percutaneous Coronary Intervention (PCI) the risk of bleeding increase due to concomitant prescription of antiplatelet agents. The 2016 European Society of Cardiology( ESC) guidelines for non valvular AF provide clear recommendations for triple therapy , Combination of two anti-platelet and oral anticoagulant in patients with underlying AF undergoing PCI, either electively or for acute coronary syndrome (ACS). The risk of such therapy is based on treatment duration and patient characteristics.
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
92 Pan London ‘know your pulse’ awareness campaign during world heart rhythm week 2017
Introduction: Atrial fibrillation (AF) is the most common cardiac arrhythmia and is responsible for 1 in 5 strokes. AF is frequently asymptomatic and it is estimated that there are 68,000 people in London living with the condition undetected. A simple check of the regularity of an individual ’s pulse rhythm can help to improve detection rates and ensure people are initiated on an appropriate treatment to reduce their risk of AF-related stroke.
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
103 How is our local AF management? The management of atrial fibrillation (af) in coventry and rugby clinical commissioning group (ccg), england compared to national data and nice (national institute for clinical excellence) 2014
Background: AF is the most common cardiac arrhythmia affecting 2% in the UK.AF carriers 5 fold risk of stroke, with increased stroke mortality, morbidity& longer hospital stay.CHADSVAs guides anti-coagulation ( ≥1 anti-coagulate)Risk factor modification reduces AF reoccurrenceNurse led clinics reduce AF related stroke risk, improve AF management, risk factor reduction whilst providing safe anticoagulation.
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
107 Thoracoscopicepicardial left atrial appendage occlusion in stroke prevention in non-valvular atrial fibrillation - long-term resultes
Background: Oral anticoagulation remainse the standard of care for stroke prevention in atrial fibrillation. However not every patient is feasible for this therapy. Because approximately 90% thrombotic material originate from the left atrial appendage (LAA), it is assumed that the LAA closure might be not inferior to oral anticoagulation.
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
109 Accuracy of test results for Direct Oral Anticoagulants (DOACs) and Warfarin- importance of External Quality Assessment (EQA)
Introduction: Lifelong anticoagulation is widely used in atrial fibrillation (AF) and anticoagulation with warfarin therapy is effective in stroke prevention in AF patients. The introduction of Direct Oral Anticoagulants (DOACS) has increased choice in anticoagulant control. However one concern with DOACs is the measurement of these drugs. It has been established in clinical trials that these drugs are non inferior or superior to warfarin therapy without the need to monitor but in some circumstances we still need to be able to measure the concentrations and effects of these drugs.
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
112 “I don’t know how you can be the decision maker when you don’t understand”: designing a tailored E-health intervention to empower patients living with non-valvular atrial fibrillation
Background: Prevention of thromboembolism is key in individuals with non-valvular atrial fibrillation (NVAF) and nonadherence to oral anticoagulant (OAC) therapy is a frequent causative factor of stroke. Many factors contribute to the complexity of medication nonadherence. Thus, education aimed at changing health behaviors must be tailored to address the unique internal motivations and information needs of those confronted with the daily choice to take a medication to prevent stroke. Delivery of tailored health education and medication reminders may be an effective way to empower individuals with NVAF and in consequence, i...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
115 Anticoagulation in atrial fibrillation – a single-centre audit on patient education, stroke and bleeding risk assessments and use of direct oral anticoagulants (DOACs)
Objective: To assess adherence to the National Institute of Health and Care Excellence (NICE) guidelines on management of atrial fibrillation in adults, specifically the provision of a personalised package of care and information to patients, and stroke and bleeding risk assessments. To assess the frequency of use of DOACs as the anticoagulant of choice.
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
124 GP-led anticoagulation counselling for non-valvular atrial fibrillation (AF) in the community is neither comprehensive nor accurate: Results from a service improvement project.
Background: Stroke risk in NVAF can be reduced significantly by anticoagulation with either warfarin or the non- vitamin K antagonist (NOACs). NICE recommendations state that NOACs are as efficacious but also associated with significantly less intracranial bleeding compared to Warfarin and in this sense are safer than warfarin. Additionally NOACs do not require regular monitoring of their anticoagulant effects and therefore offer convenience to the patient. However they are not as tried and tested as warfarin and at the time of our study, did not have an available agent to reverse their effects in the event of a bleeding c...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
130 Improving the implementation of anti-coagulation therapy in AF patients at risk of stroke in a primary care setting
Background: Atrial fibrillation (AF) is the most common sustained arrhythmia of the heart and is of increasing prevalence1. There are strong implications of increased stroke risk in AF patients2. In particular, AF related stroke carries a near 50% risk of persisting disability and directly increases costs for treatment by over a third in comparison with non AF stroke patients3,4. As an estimated contributing cause of 15-20% of all strokes, the economic and societal impact of AF is of extreme importance5. To monitor how efficiently stroke prevention is implemented in a primary care setting we will identify those ‘at risk...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
131 ‘Silent’ atrial tachyarrhythmia and potential cryptogenic stroke: a ‘real-world’ study
Background: Atrial Fibrillation (AFib) and Flutter (AFl) are known to be associated with embolic stroke and current guidelines rightly recommend anticoagulation in these patients to reduce this risk. However, the management of other Atrialtachyarrhythmias (ATAs) in relation to stroke is unclear. The aim of this study was to explore whether ATAs (other than AFib/AFl) could be associated with stroke or progress to AF.
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research
