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Specialty: Neurology
Source: JAMA Neurology

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Total 364 results found since Jan 2013.

Stroke Diagnosis and Treatment in the Emergency Department —Reply
In Reply I thank Rota and colleagues for their comments on my Viewpoint, which challenged the status quo concerning the requirement of a neurologist to initiate the tissue plasminogen activator (tPA) protocol for an obvious diagnosis of acute stroke in the emergency department (ED). In today ’s world of Instagram, Facebook, and Twitter feeds, we all need to embrace change. A few years ago, for instance, no one knew what Altmetric represented. Today, all of us crave the statistics reported by Altmetric, which recognizes our work via the number of tweets and “cross-talk” across mult iple platforms. Funding, data collec...
Source: JAMA Neurology - January 23, 2017 Category: Neurology Source Type: research

Recurrence of Posterior Circulation Childhood Arterial Ischemic Stroke
This cohort study investigates the incidence of the recurrence of childhood arterial ischemic stroke in the posterior and anterior circulations to determine if the risk differs between the 2 locations.
Source: JAMA Neurology - January 23, 2017 Category: Neurology Source Type: research

Association of Collateral Blood Vessels With Neurological Outcome After Stroke
This cohort study assesses the association between the presence of collateral vessels identified using arterial spin labeling magnetic resonance imaging and neurologic outcome in patients after acute ischemic stroke.
Source: JAMA Neurology - February 13, 2017 Category: Neurology Source Type: research

Response to Endovascular Therapy for Acute Ischemic Stroke
To the Editor Recent data from randomized clinical trials provide clear evidence that endovascular treatment for acute ischemic stroke because of large vessel anterior circulation occlusion improves clinical outcomes for patients. These studies reported that most patients had an occlusion of the first segment (M1) of the middle cerebral artery and less than 10% in the M2 segment. The retrospective multicenter study conducted by Sarraj et al reports that endovascular treatment is safe and effective for an occlusion of the M2 segment. However, the literature reports different definitions for the M1 and M2 segments, which may...
Source: JAMA Neurology - February 27, 2017 Category: Neurology Source Type: research

Predictive Validity of Etiologic Stroke Classification
This study examines whether etiologic stroke subtyping using 3 different classification systems identifies different disease processes that can be recognized through their different clinical courses.
Source: JAMA Neurology - February 27, 2017 Category: Neurology Source Type: research

Endovascular Thrombectomy for Acute Ischemic Stroke
This study compares the functional independence at 3 months between patients treated for acute ischemic stroke under the drip-and-ship paradigm and those treated on site (mothership paradigm).
Source: JAMA Neurology - March 20, 2017 Category: Neurology Source Type: research

Cirrhosis and Stroke in a Nationally Representative Cohort
This cohort study of Medicare claims data investigates the association between cirrhosis and various stroke types.
Source: JAMA Neurology - June 5, 2017 Category: Neurology Source Type: research

Mechanical Thrombectomy in Acute Stroke
To the Editor In their recent article, Coutinho et al address whether patients who have had an acute stroke with proximal occlusion should undergo intravenous thrombolysis (IVT) before a mechanical thrombectomy (MT). In this analysis of pooled data from the SWIFT and STAR trials, MT after IVT did not appear to provide clinical benefits over MT alone. The authors concluded that randomized clinical trials should confirm their observation.
Source: JAMA Neurology - July 10, 2017 Category: Neurology Source Type: research

Mechanical Thrombectomy in Acute Stroke —Reply
In Reply We read with interest the letter by Seners and colleagues regarding our recent publication. The possibility of early recanalization among patients with acute ischemic stroke and a proximal intracranial occlusion was underestimated in the recent trials on mechanical thrombectomy (MT) because vascular imaging was in part done after starting intravenous thrombolysis (IVT), particularly in the MR CLEAN trial. However, Seners et al observed higher recanalization rates for M1 and M2 occlusions at an early stage, but this was not the case for carotid occlusions. Additionally, they defined early recanalization as happenin...
Source: JAMA Neurology - July 10, 2017 Category: Neurology Source Type: research

Birth in a High Stroke Mortality State, Race, and Risk of Dementia
This cohort study examines the risk of dementia in individuals who are born in the Stroke Belt but later reside in California.
Source: JAMA Neurology - July 31, 2017 Category: Neurology Source Type: research

Recrudescence of Deficits After Stroke
This crossover cohort, case-control study uses medical records from the Research Patient Data Repository to determine the features, triggers, and risk factors of poststroke recrudescence among patients with a previous stroke.
Source: JAMA Neurology - August 7, 2017 Category: Neurology Source Type: research

Childhood Body Mass Index and First Adult Ischemic Stroke
This population-based cohort study of schoolchildren born from the 1930s through the 1980s in Denmark investigates whether childhood body mass index (BMI) and change in BMI are associated with adult ischemic stroke and assesses whether the associations are age dependent or influenced by birth weight.
Source: JAMA Neurology - August 21, 2017 Category: Neurology Source Type: research

Longitudinal Care for Young Adults With Stroke
This Viewpoint discusses a longitudinal care program designed to explore and address unmet needs of stroke survivors.
Source: JAMA Neurology - August 21, 2017 Category: Neurology Source Type: research

Low-Dose vs Standard-Dose Alteplase for Patients With Acute Ischemic Stroke
This secondary analysis reports on the association of low-dose and standard-dose intravenous alteplase treatment with age, ethnicity (Asian vs non-Asian), and severity of acute ischemic stroke among patients in the ENCHANTED randomized clinical trial.
Source: JAMA Neurology - October 2, 2017 Category: Neurology Source Type: research