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Specialty: Neurology
Source: JAMA Neurology

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Total 364 results found since Jan 2013.

Follow-up Infarct Volume and Functional Outcome After Endovascular Therapy in Acute Ischemic Stroke
This pooled data analysis of 7 randomized clinical trials of thrombectomy for acute ischemic stroke examines whether follow-up infarct volume mediates the relationship between endovascular therapy and functional outcome in patients with acute ischemic stroke.
Source: JAMA Neurology - January 7, 2019 Category: Neurology Source Type: research

Clinical Care and In-Hospital Outcomes of Asian American Patients With Acute Ischemic Stroke
This analysis compares the characteristics, care, and outcomes of Asian American and white patients with acute ischemic stroke at hospitals participating in the Get With The Guidelines –Stroke program.
Source: JAMA Neurology - January 22, 2019 Category: Neurology Source Type: research

Pioglitazone Therapy in Patients With Stroke and Prediabetes
This post hoc analysis of Insulin Resistance Intervention After Stroke (IRIS) randomized clinical trial assesses the association of pioglitazone vs placebo with recurrent stroke, myocardial infarction, and other cardiovascular events.
Source: JAMA Neurology - February 7, 2019 Category: Neurology Source Type: research

Recurrent Stroke With Rivaroxaban Compared With Aspirin
This secondary analysis of a randomized clinical trial investigates whether rivaroxaban is associated with a reduction in recurrent stroke among patients with embolic stroke of undetermined source who have an increased risk of atrial fibrillation.
Source: JAMA Neurology - April 8, 2019 Category: Neurology Source Type: research

Endovascular Thrombectomy as a Means to Improve Survival in Acute Ischemic Stroke
This meta-analysis examines 90-day mortality and 90-day intracranial hemorrhage reported in trials of endovascular thrombectomy vs medical therapy cited in the 2018 American Stroke Association/American Heart Association guidelines for acute ischemic stroke.
Source: JAMA Neurology - April 8, 2019 Category: Neurology Source Type: research

Association of Black Race With Early Recurrence After Minor Ischemic Stroke or Transient Ischemic Attack
This secondary analysis of the POINT randomized clinical trial examines the association between race and risk of early ischemic stroke recurrence after a minor ischemic stroke or transient ischemic attack among US participants.
Source: JAMA Neurology - February 24, 2020 Category: Neurology Source Type: research

Enhanced Paramedic Acute Stroke Treatment Assessment and Thrombolysis Delivery in Emergency Stroke Care
This cluster randomized clinical trial sought to examine whether adding enhanced paramedic assessment to standard care would result in increased rates of thrombolysis in patients experiencing stroke.
Source: JAMA Neurology - April 13, 2020 Category: Neurology Source Type: research

Characteristics of Recurrent Ischemic Stroke After ESUS
This secondary analysis of a randomized clinical trial assesses the subtype of recurrent ischemic stroke after embolic stroke of underdetermined source, the interaction with treatment assignment, and the consistency of cerebral location of the qualifying and recurrent strokes in the study population of the NAVIGATE-ESUS trial.
Source: JAMA Neurology - July 6, 2020 Category: Neurology Source Type: research

Ticagrelor Plus Aspirin in Preventing Disabling Stroke
This randomized clinical trial evaluates the superiority of ticagrelor added to aspirin in preventing disabling stroke and identifies factors associated with recurrent disabling stroke.
Source: JAMA Neurology - November 7, 2020 Category: Neurology Source Type: research

Sex Disparities in Enrollment in Recent Randomized Clinical Trials of Acute Stroke
This meta-analysis assesses if women were underenrolled in contemporary randomized clinical trials of acute stroke therapies published in 9 major journals, after accounting for their representation in underlying stroke populations.
Source: JAMA Neurology - April 26, 2021 Category: Neurology Source Type: research

Assessment of Recurrent Stroke Risk in Patients With a Carotid Web
This cohort study assesses the recurrent stroke risk in a population of patients with a large vessel occlusion stroke of the anterior circulation and ipsilateral carotid web.
Source: JAMA Neurology - May 10, 2021 Category: Neurology Source Type: research

Questions on Predicting Early Neurological Deterioration in Patients With Minor Stroke and Large-Vessel Occlusion
To the Editor We read with great interest the article by Seners and colleagues in which they investigated predictors of early neurological deterioration of presumed ischemic origin (ENDi) in large-vessel occlusion stroke with minor clinical deficits and developed a 4-point risk prediction score of ENDi. This is a common and probably underrecognized problem in large-vessel occlusion stroke, and characterizing patients at risk of ENDi is highly relevant for patient management.
Source: JAMA Neurology - July 6, 2021 Category: Neurology Source Type: research

Efficacy and Safety of Ticagrelor and Aspirin in Patients With Moderate Ischemic Stroke
This exploratory analysis of the THALES trial evaluates the efficacy and safety of ticagrelor plus aspirin in patients with moderate ischemic stroke (National Institutes of Health Stroke Scale score of 4 to 5).
Source: JAMA Neurology - July 9, 2021 Category: Neurology Source Type: research

LV Dysfunction Among Patients With Embolic Stroke of Undetermined Source and the Effect of Rivaroxaban vs Aspirin
This post hoc analysis evaluates whether anticoagulation is superior to aspirin in reducing recurrent stroke in patients with embolic stroke of undetermined source and left ventricular dysfunction.
Source: JAMA Neurology - October 25, 2021 Category: Neurology Source Type: research

Infarct on Brain Imaging, Subsequent Ischemic Stroke, and Clopidogrel-Aspirin Efficacy
This post hoc analysis of a randomized clinical trial investigates whether the association of clopidogrel-aspirin treatment with stroke recurrence in patients with minor stroke or high-risk transient ischemic attack is modified by the presence of infarct on imaging attributed to the index event.
Source: JAMA Neurology - January 18, 2022 Category: Neurology Source Type: research