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Source: Circulation

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Total 925 results found since Jan 2013.

Direct Oral Anticoagulants Versus Warfarin Across the Spectrum of Kidney Function: Patient-Level Network Meta-Analyses From COMBINE AF
CONCLUSIONS: Standard-dose DOACs are safer and more effective than warfarin down to a CrCl of at least 25 mL/min. Lower-dose DOACs do not significantly lower the incidence of bleeding or ICH compared with standard-dose DOACs but are associated with a higher incidence of S/SE and death. These findings support the use of standard-dose DOACs over warfarin in patients with kidney dysfunction.PMID:37042255 | DOI:10.1161/CIRCULATIONAHA.122.062752
Source: Circulation - April 12, 2023 Category: Cardiology Authors: Josephine Harrington Anthony P Carnicelli Kaiyuan Hua Lars Wallentin Manesh R Patel Stefan H Hohnloser Robert P Giugliano Keith A A Fox Ziad Hijazi Renato D Lopes Sean D Pokorney Hwanhee Hong Christopher B Granger Source Type: research

Cardiovascular Disease Risk Factors in Women: The Impact of Race and Ethnicity: A Scientific Statement From the American Heart Association
Circulation. 2023 Apr 10. doi: 10.1161/CIR.0000000000001139. Online ahead of print.ABSTRACTCardiovascular disease is the leading cause of death in women, yet differences exist among certain racial and ethnic groups. Aside from traditional risk factors, behavioral and environmental factors and social determinants of health affect cardiovascular health and risk in women. Language barriers, discrimination, acculturation, and health care access disproportionately affect women of underrepresented races and ethnicities. These factors result in a higher prevalence of cardiovascular disease and significant challenges in the diagno...
Source: Circulation - April 10, 2023 Category: Cardiology Authors: Laxmi S Mehta Gladys P Velarde Jennifer Lewey Garima Sharma Rachel M Bond Ana Navas-Acien Amanda M Fretts Gayenell S Magwood Eugene Yang Roger S Blumenthal Rachel-Maria Brown Jennifer H Mieres American Heart Association Cardiovascular Disease and Stroke i Source Type: research

Severe Infection and Risk of Cardiovascular Disease: A Multicohort Study
CONCLUSIONS: Infections severe enough to require hospital treatment were associated with increased risks for major cardiovascular disease events immediately after hospitalization. A small excess risk was also observed in the long-term, but residual confounding cannot be excluded.PMID:36971007 | DOI:10.1161/CIRCULATIONAHA.122.061183
Source: Circulation - March 27, 2023 Category: Cardiology Authors: Pyry N Sipil ä Joni V Lindbohm G David Batty Nelli Heikkil ä Jussi Vahtera Sakari Suominen Ari V äänänen Aki Koskinen Solja T Nyberg Seppo Meri Jaana Pentti Charlotte Warren-Gash Andrew C Hayward Mika Kivim äki Source Type: research

Pharmacology and Clinical Development of Factor XI Inhibitors
This article reviews the rationale, pharmacology, results of medium or small phase 2 studies, and future perspectives of drugs inhibiting FXI.PMID:36913497 | DOI:10.1161/CIRCULATIONAHA.122.062353
Source: Circulation - March 13, 2023 Category: Cardiology Authors: Antonio Greco Claudio Laudani Marco Spagnolo Federica Agnello Denise Cristiana Faro Simone Finocchiaro Marco Legnazzi Maria Sara Mauro Placido Maria Mazzone Giovanni Occhipinti Carla Rochira Lorenzo Scalia Davide Capodanno Source Type: research

Mechanical Thrombectomy Global Access For Stroke (MT-GLASS): A Mission Thrombectomy (MT-2020 Plus) Study
CONCLUSIONS: Access to MT on a global level is extremely low, with enormous disparities between countries by income level. The significant determinants of MT access are the country's per capita gross national income, prehospital LVO triage policy, and MT operator and center availability.PMID:36883458 | DOI:10.1161/CIRCULATIONAHA.122.063366
Source: Circulation - March 8, 2023 Category: Cardiology Authors: Kaiz S Asif Fadar O Otite Shashvat M Desai Nabeel Herial Violiza Inoa Fawaz Al-Mufti Ashutosh P Jadhav Adam A Dmytriw Alicia Castonguay Priyank Khandelwal Jennifer Potter-Vig Viktor Szeder Tanzila Kulman Victor Urrutia Hesham Masoud Gabor Toth Kaustubh Li Source Type: research

Eliminating Medication Copayments for Low-income Older Adults at High Cardiovascular Risk: A Randomized Controlled Trial
Conclusions: In low-income adults at high cardiovascular risk, eliminating copayments (average $35 a month) did not improve clinical outcomes or reduce healthcare costs, despite a modest improvement in adherence to medications.PMID:36871215 | DOI:10.1161/CIRCULATIONAHA.123.064188
Source: Circulation - March 5, 2023 Category: Cardiology Authors: David J T Campbell Chad Mitchell Brenda R Hemmelgarn Marcello Tonelli Peter Faris Jianguo Zhang Ross T Tsuyuki Jane Fletcher Flora Au Scott Klarenbach Derek V Exner Braden J Manns Interdisciplinary Chronic Disease Collaboration Source Type: research

Self-management Support Using Advertising Principles for Older Low Income Adults at High Cardiovascular Risk: a Randomized Controlled Trial
Conclusions: In low-income older adults, a tailored SMES program using advertising principles reduced the rate of clinical outcomes compared with usual care, though the mechanisms of improvement are unclear and further studies are required.PMID:36871212 | DOI:10.1161/CIRCULATIONAHA.123.064189
Source: Circulation - March 5, 2023 Category: Cardiology Authors: David J T Campbell Marcello Tonelli Brenda R Hemmelgarn Peter Faris Jianguo Zhang Flora Au Ross T Tsuyuki Chad Mitchell Raj Pannu Tavis Campbell Noah Ivers Jane Fletcher Derek V Exner Braden J Manns Interdisciplinary Chronic Disease Collaboration Source Type: research