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Source: Circulation
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Total 925 results found since Jan 2013.
Indobufen or Aspirin on Top of Clopidogrel after Coronary Drug-eluting Stent Implantation (OPTION): a Randomized, Open-label, Endpoint-blinded, Non-inferiority Trial
Conclusions: In Chinese patients with negative cardiac troponin undergoing DES implantation, indobufen plus clopidogrel DAPT compared with aspirin plus clopidogrel DAPT significantly reduced the risk of 1-year net clinical outcomes, which was mainly driven by a reduction in bleeding events without an increase in ischemic events.PMID:36335890 | DOI:10.1161/CIRCULATIONAHA.122.062762
Source: Circulation - November 6, 2022 Category: Cardiology Authors: Hongyi Wu Lili Xu Xin Zhao Huanyi Zhang Kang Cheng Xiaoyan Wang Manhua Chen Guangping Li Jiangnan Huang Jun Lan Guanghe Wei Chi Zhang Yinman Wang Juying Qian Junbo Ge Source Type: research
Extracorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock: Results of the ECMO-CS Randomized Clinical Trial
Conclusions: Immediate implementation of VA-ECMO in patients with rapidly deteriorating or severe cardiogenic shock did not improve clinical outcomes compared with an early conservative strategy that permitted downstream use of VA-ECMO in case of worsening hemodynamic status. Clinical Trial Registration: URL: https://www.clinicaltrials.gov; Unique identifier NCT02301819.PMID:36335478 | DOI:10.1161/CIRCULATIONAHA.122.062949
Source: Circulation - November 6, 2022 Category: Cardiology Authors: Petr Ostadal Richard Rokyta Jiri Karasek Andreas Kruger Dagmar Vondrakova Marek Janotka Jan Naar Jana Smalcova Marketa Hubatova Milan Hromadka Stefan Volovar Miroslava Seyfrydova Jiri Jarkovsky Michal Svoboda Ales Linhart Jan Belohlavek ECMO-CS Investigat Source Type: research
Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses
CONCLUSIONS: In people without manifest cardiovascular disease or diabetes, mild-to-moderate kidney dysfunction is causally related to risk of CHD, highlighting the potential value of preventive approaches that preserve and modulate kidney function.PMID:36314129 | DOI:10.1161/CIRCULATIONAHA.122.060700
Source: Circulation - October 31, 2022 Category: Cardiology Authors: Liam Gaziano Luanluan Sun Matthew Arnold Steven Bell Kelly Cho Stephen K Kaptoge Rebecca J Song Stephen Burgess Daniel C Posner Katja Mosconi Cassianne Robinson-Cohen Amy Mason Thomas R Bolton Ran Tao Elias Allara Petra Schubert Lingyan Chen James R Stale Source Type: research
Mutant Phosphodiesterase 3A Protects From Hypertension-Induced Cardiac Damage
CONCLUSIONS: Although in vascular smooth muscle, PDE3A mutations cause hypertension, they confer protection against hypertension-induced cardiac damage in hearts. Nonselective PDE3A inhibition is a final, short-term option in heart failure treatment to increase cardiac cAMP and improve contractility. Our data argue that mimicking the effect of PDE3A mutations in the heart rather than nonselective PDE3 inhibition is cardioprotective in the long term. Our findings could facilitate the search for new treatments to prevent hypertension-induced cardiac damage.PMID:36259389 | DOI:10.1161/CIRCULATIONAHA.122.060210
Source: Circulation - October 19, 2022 Category: Cardiology Authors: Maria Ercu Michael B M ücke Tamara Pallien Lajos Mark ó Anastasiia Sholokh Carolin Sch ächterle Atakan Aydin Alexa Kidd Stephan Walter Yasmin Esmati Brandon J McMurray Daniella F Lato Daniele Yumi Sunaga-Franze Philip H Dierks Barbara Isabel Montesinos Source Type: research
Leveraging Implementation Science for Cardiovascular Health Equity: A Scientific Statement From the American Heart Association
Circulation. 2022 Oct 10:101161CIR0000000000001096. doi: 10.1161/CIR.0000000000001096. Online ahead of print.ABSTRACTReducing cardiovascular disease disparities will require a concerted, focused effort to better adopt evidence-based interventions, in particular, those that address social determinants of health, in historically marginalized populations (ie, communities excluded on the basis of social identifiers like race, ethnicity, and social class and subject to inequitable distribution of social, economic, physical, and psychological resources). Implementation science is centered around stakeholder engagement and, by vi...
Source: Circulation - October 10, 2022 Category: Cardiology Authors: Nathalie Moise Crystal W Cen é Rachel G Tabak Deborah R Young Katherine T Mills Utibe R Essien Cheryl A M Anderson Francisco Lopez-Jimenez American Heart Association Council on Epidemiology and Prevention; Council on Hypertension; and Stroke Council Source Type: research
Everolimus-Eluting Stents or Bypass Surgery for Multivessel Coronary Artery Disease: Extended Follow-up Outcomes of Multicenter Randomized Controlled BEST Trial
CONCLUSIONS: In patients with multivessel coronary artery disease, there were no significant differences between PCI and CABG in the incidence of major adverse cardiac events, safety composite end point, and all-cause mortality during extended-follow-up.PMID:36121700 | DOI:10.1161/CIRCULATIONAHA.122.062188
Source: Circulation - September 19, 2022 Category: Cardiology Authors: Jung-Min Ahn Do-Yoon Kang Sung-Cheol Yun Seung Ho Hur Hun-Jun Park Damras Tresukosol Woon Chol Kang Hyuck Moon Kwon Seung-Woon Rha Do-Sun Lim Myung-Ho Jeong Bong-Ki Lee He Huang Young Hyo Lim Jang Ho Bae Byung-Ok Kim Tiong Kiam Ong Sung Gyun Ahn Cheol-Hyu Source Type: research
Correction to: Heart Disease and Stroke Statistics-2022 Update: A Report From the American Heart Association
Circulation. 2022 Sep 6;146(10):e141. doi: 10.1161/CIR.0000000000001074. Epub 2022 Sep 6.NO ABSTRACTPMID:36067280 | DOI:10.1161/CIR.0000000000001074
Source: Circulation - September 6, 2022 Category: Cardiology Source Type: research
