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Source: Circulation

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Total 925 results found since Jan 2013.

Biomarker-Based Risk Prediction With The ABC-AF Scores in Patients With Atrial Fibrillation Not Receiving Oral Anticoagulation
Conclusions: The biomarker-based ABC-AF scores showed better discrimination than traditional risk scores and were recalibrated for precise risk estimation in patients not receiving oral anticoagulation. They can now provide improved decision support regarding treatment of an individual patient with AF.PMID:33849281 | DOI:10.1161/CIRCULATIONAHA.120.053100
Source: Circulation - April 14, 2021 Category: Cardiology Authors: Alexander P Benz Ziad Hijazi Johan Lindb äck Stuart J Connolly John W Eikelboom Jonas Oldgren Agneta Siegbahn Lars Wallentin Source Type: research

Perioperative Neurological Evaluation and Management to Lower the Risk of Acute Stroke in Patients Undergoing Noncardiac, Nonneurological Surgery: A Scientific Statement From the American Heart Association/American Stroke Association
Circulation. 2021 Apr 8:CIR0000000000000968. doi: 10.1161/CIR.0000000000000968. Online ahead of print.ABSTRACTPerioperative stroke is a potentially devastating complication in patients undergoing noncardiac, nonneurological surgery. This scientific statement summarizes established risk factors for perioperative stroke, preoperative and intraoperative strategies to mitigate the risk of stroke, suggestions for postoperative assessments, and treatment approaches for minimizing permanent neurological dysfunction in patients who experience a perioperative stroke. The first section focuses on preoperative optimization, including...
Source: Circulation - April 8, 2021 Category: Cardiology Authors: Curtis Benesch Laurent G Glance Colin P Derdeyn Lee A Fleisher Robert G Holloway Steven R Mess é Christina Mijalski M Timothy Nelson Martha Power Babu G Welch American Heart Association Stroke Council; Council on Arteriosclerosis, Thrombosis and Vascular Source Type: research

Primary Outcome Evaluation of a Next Generation Left Atrial Appendage Closure Device: Results from the PINNACLE FLX Trial
Conclusions: LAA closure with this next generation LAA closure device was associated with a low incidence of adverse events and a high incidence of anatomic closure. Clinical Trial Registration: URL https://clinicaltrials.gov Unique Identifier NCT02702271.PMID:33820423 | DOI:10.1161/CIRCULATIONAHA.120.050117
Source: Circulation - April 6, 2021 Category: Cardiology Authors: Saibal Kar Shephal K Doshi Ashish Sadhu Rodney Horton Jose Osorio Christopher Ellis James Stone Manish Shah Srinivas R Dukkipati Stuart Adler Devi G Nair Jamie Kim Oussama Wazni Matthew J Price Federico M Asch David R Holmes Robert D Shipley Nicole T Gord Source Type: research

Adverse Pregnancy Outcomes and Cardiovascular Disease Risk: Unique Opportunities for Cardiovascular Disease Prevention in Women: A Scientific Statement From the American Heart Association
Circulation. 2021 Mar 29:CIR0000000000000961. doi: 10.1161/CIR.0000000000000961. Online ahead of print.ABSTRACTThis statement summarizes evidence that adverse pregnancy outcomes (APOs) such as hypertensive disorders of pregnancy, preterm delivery, gestational diabetes, small-for-gestational-age delivery, placental abruption, and pregnancy loss increase a woman's risk of developing cardiovascular disease (CVD) risk factors and of developing subsequent CVD (including fatal and nonfatal coronary heart disease, stroke, peripheral vascular disease, and heart failure). This statement highlights the importance of recognizing APOs...
Source: Circulation - March 29, 2021 Category: Cardiology Authors: Nisha I Parikh Juan M Gonzalez Cheryl A M Anderson Suzanne E Judd Kathryn M Rexrode Mark A Hlatky Erica P Gunderson Jennifer J Stuart Dhananjay Vaidya American Heart Association Council on Epidemiology and Prevention; Council on Arteriosclerosis, Thrombos Source Type: research

Letter by Saleh Regarding Article, "Carotid Atherosclerosis Evolution When Targeting a Low-Density Lipoprotein Cholesterol Concentration & lt;70 mg/dL After an Ischemic Stroke of Atherosclerotic Origin"
Circulation. 2021 Mar 23;143(12):e790-e791. doi: 10.1161/CIRCULATIONAHA.120.050617. Epub 2021 Mar 22.NO ABSTRACTPMID:33750204 | DOI:10.1161/CIRCULATIONAHA.120.050617
Source: Circulation - March 22, 2021 Category: Cardiology Authors: Christian Saleh Source Type: research

Cerebral Embolic Protection and Outcomes of Transcatheter Aortic Valve Replacement: Results from the TVT Registry
Conclusions: In this nationally-representative observational study, we did not find an association between EPD use for TAVR and in-hospital stroke in our primary IV analysis, and found only a modestly lower risk of in-hospital stroke in our secondary propensity-weighted analysis. These findings provide a strong basis for large-scale RCTs to test whether EPDs provide meaningful clinical benefit for patients undergoing TAVR.PMID:33619968 | DOI:10.1161/CIRCULATIONAHA.120.052874
Source: Circulation - February 23, 2021 Category: Cardiology Authors: Neel M Butala Raj Makkar Eric A Secemsky Dianne Gallup Guillaume Marquis-Gravel Andrzej S Kosinski Sreekanth Vemulapalli Javier A Valle Steven M Bradley Tarun Chakravarty Robert W Yeh David J Cohen Source Type: research

Bending the Curve in Cardiovascular Disease Mortality: Bethesda + 40 and Beyond
This report summarizes the relevant research, policy, and practice opportunities discussed at the symposium.PMID:33617315 | DOI:10.1161/CIRCULATIONAHA.120.046501
Source: Circulation - February 22, 2021 Category: Cardiology Authors: David Calvin Goff Sadiya Sana Khan Donald Lloyd-Jones Donna K Arnett Mercedes R Carnethon Darwin R Labarthe Matthew Shane Loop Russell V Luepker Michael V McConnell George A Mensah Mahasin S Mujahid Martin Enrique O'Flaherty Dorairaj Prabhakaran V éroniq Source Type: research

Maternal Stroke: A Call for Action.
Abstract Maternal mortality rates have been steadily increasing in the United States, and cardiovascular mortality is the leading cause of death among pregnant and postpartum women. Maternal stroke accounts for a significant burden of cardiovascular mortality. Data suggest that rates of maternal stroke have been increasing in recent years. Advancing maternal age at the time of birth and the increasing prevalence of traditional cardiovascular risk factors, and other risk factors, as well, such as hypertensive disorders of pregnancy, migraine, and infections, may contribute to increased rates of maternal stroke. In ...
Source: Circulation - February 16, 2021 Category: Cardiology Authors: Elgendy IY, Bukhari S, Barakat AF, Pepine CJ, Lindley KJ, Miller EC, American College of Cardiology Cardiovascular Disease in Women Committee Tags: Circulation Source Type: research

Comparison of the Efficacy and Safety Outcomes of Edoxaban in 8040 Women Versus 13 065 Men With Atrial Fibrillation in the ENGAGE AF-TIMI 48 Trial.
CONCLUSIONS: Despite many differences in baseline characteristics between women and men and higher baseline endogenous factor Xa levels in women, the intensity of anticoagulation achieved with edoxaban between the sexes was similar. Treatment with higher-dose edoxaban regimen resulted in an even greater reduction in hemorrhagic stroke and several serious bleeding outcomes in women than in men, whereas the efficacy profile was similar between sexes. PMID: 33587659 [PubMed - as supplied by publisher]
Source: Circulation - February 16, 2021 Category: Cardiology Authors: Zelniker TA, Ardissino M, Andreotti F, O'Donoghue ML, Yin O, Park JG, Murphy SA, Ruff CT, Lanz HJ, Antman EM, Braunwald E, Giugliano RP, Merlini PA Tags: Circulation Source Type: research