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Source: Journal of the American College of Cardiology

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Total 269 results found since Jan 2013.

Bariatric Surgery and the Risk of New-Onset Atrial Fibrillation in Swedish  Obese Subjects
BackgroundObesity is a risk factor for atrial fibrillation, which in turn is associated with stroke, heart failure, and increased all-cause mortality.ObjectivesThe authors investigated whether weight loss through bariatric surgery may reduce the risk of new-onset atrial fibrillation.MethodsSOS (Swedish Obese Subjects) is a prospective matched cohort study conducted at 25 surgical departments and 480 primary healthcare centers in Sweden. The cohort was recruited between 1987 and 2001. Among 4,021 obese  individuals with sinus rhythm and no history of atrial fibrillation, 2,000 underwent bariatric surgery (surgery group), a...
Source: Journal of the American College of Cardiology - December 5, 2016 Category: Cardiology Source Type: research

Causes of Death in Anticoagulated Patients With Atrial Fibrillation
ConclusionsIn contemporary AF trials, most deaths were cardiac-related, whereas stroke and bleeding represented  only a small subset of deaths. Interventions beyond anticoagulation are needed to further reduce mortality in AF.
Source: Journal of the American College of Cardiology - December 5, 2016 Category: Cardiology Source Type: research

Anticoagulation Treatment for Stroke Prevention in Atrial Fibrillation Is Increasing, But Further Improvements Needed
A recent paper by Hsu et  al.(1) assessed antithrombotic treatment among atrial fibrillation (AF) patients. The data, from the American College of Cardiology PINNACLE (Practice Innovation and Clinical Excellence) registry between 2008 and 2012, showed that 61.8% of patients with moderate-to-high stroke risk received anticoagulant therapy with either warfarin or newer direct oral anticoagulants (DOACs). The investigators and an editorial commentary noted the alarming prevalence of aspirin-only treatment despite clear evidence that anticoagulants are superior for prevention of thromboembolism in AF (1,2).
Source: Journal of the American College of Cardiology - November 29, 2016 Category: Cardiology Source Type: research

Reply Anticoagulation Treatment for Stroke Prevention in Atrial Fibrillation Is Increasing, But Further Improvements Needed
We are appreciative of Dr. Brown and colleagues and their interest in our recent paper in theJournal(1) regarding prescription of aspirin instead of oral anticoagulation (OAC) in patients with atrial fibrillation (AF) who are at intermediate-to-high thromboembolic risk in the American College of Cardiology National Cardiovascular Data Registry ’s PINNACLE (Practice Innovation and Clinical Excellence) Registry. They appropriately highlight some of our main findings, including that OAC prescription was selected in 61.8% of patients with a CHADS2 score  ≥2 (meaning 38.2% of patients were treated with aspirin alone) and 5...
Source: Journal of the American College of Cardiology - November 29, 2016 Category: Cardiology Source Type: research

Left Atrial Appendage Isolation in Patients  With Longstanding Persistent AF Undergoing Catheter Ablation BELIEF Trial
ConclusionsThis randomized study showed that both after a single procedure and after redo procedures in patients with LSPAF, empirical electrical isolation of the LAA improved long-term freedom from atrial arrhythmias without increasing complications. (Effect of Empirical Left Atrial Appendage Isolation on Long-term Procedure Outcome in Patients With Persistent or Longstanding Persistent Atrial Fibrillation Undergoing Catheter Ablation [BELIEF]; NCT01362738)
Source: Journal of the American College of Cardiology - October 25, 2016 Category: Cardiology Source Type: research

Single Antiplatelet Therapy Following Left Atrial Appendage Closure in Patients With Contraindication to Anticoagulation
Left atrial appendage closure (LAAC) has emerged as an alternative to warfarin for stroke prevention in patients with nonvalvular atrial fibrillation (NVAF). Optimal antithrombotic therapy following LAAC is  an unresolved issue and current anticoagulation and antiplatelet strategies after LAAC remain empirical. In the PROTECT-AF (Watchman left atrial appendage system for embolic protection in patients with atrial fibrillation) trial, patients received short-term (45 days) anticoagulation followed by d ual antiplatelet therapy (DAPT) for a period of 6 months and then lifelong aspirin(1). In patients with a contraindication...
Source: Journal of the American College of Cardiology - October 18, 2016 Category: Cardiology Source Type: research

GW27-e1260 The DNAH11 rs12670798 single nucleotide polymorphism is associated with the risk of coronary artery disease and ischemic stroke
Source: Journal of the American College of Cardiology - October 11, 2016 Category: Cardiology Source Type: research

GW27-e0484 Correlation of platelet function with recurrent ischemic vascular events in stroke patients
Source: Journal of the American College of Cardiology - October 11, 2016 Category: Cardiology Source Type: research

GW27-e0570 The predictive risk factors of silent ischemic stroke event is nocturnal blood pressure and central aortic systolic blood pressure in Metabolic Syndrome
Source: Journal of the American College of Cardiology - October 11, 2016 Category: Cardiology Source Type: research

GW27-e0689 Early morning blood pressure, pulse wave velocity, central aortic Pressure and predictive risk factors of Ischemic Stroke in masked hypertensive patients
Source: Journal of the American College of Cardiology - October 11, 2016 Category: Cardiology Source Type: research

GW27-e0183 Differences in haematological indices in chinese patients with an ischaemic stroke between those with and without a high risk patent
Source: Journal of the American College of Cardiology - October 11, 2016 Category: Cardiology Source Type: research

GW27-e0870 Is mouth better than nasal approach for brain protection in out-of-hospital cardiac arrest and stroke?
Source: Journal of the American College of Cardiology - October 11, 2016 Category: Cardiology Source Type: research

GW27-e1205 Effective cooling by CO2 Expansion for brain protection in out-of-hospital cardiac arrest and stroke- Is a regulator necessary?
Source: Journal of the American College of Cardiology - October 11, 2016 Category: Cardiology Source Type: research

GW27-e0345 The retrospective analysis of clinical characteristics and risk factors in elderly patients that complicated with pneumonia after ischemic stroke
Source: Journal of the American College of Cardiology - October 11, 2016 Category: Cardiology Source Type: research

GW27-e0346 The retrospective study of clinical characteristics and risk factors in patients that complicated with pneumonia after stroke
Source: Journal of the American College of Cardiology - October 11, 2016 Category: Cardiology Source Type: research