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Total 259 results found since Jan 2013.

A multimodal quality improvement program for delirium in stroke (S48.005)
Conclusions:Delirium prevention and management is critical to quality patient care and has not yet been effectively implemented among neurologic patients. We will discuss our ongoing efforts for delirium prevention in stroke patients.Disclosure: Dr. Ryan has nothing to disclose. Dr. Gormley has nothing to disclose. Dr. Jacobs has nothing to disclose. Dr. Cohen has received personal compensation for activities with EM Gladiators LLC. as a Medical app developer and Decibel Therapeutics as a consultant. Dr. Kimchi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ryan, S., Gormley, V., Jacobs, C., Cohen, A., Kimchi, E. Tags: Practice, Policy, and Ethics Source Type: research

Hippocampal and white matter hyperintensity volumes are associated with domain-specific cognitive decline: the Northern Manhattan Study (S18.004)
Conclusions:White matter disease burden and gray matter volume predicted decline in cognitive performance over time. Greater hippocampal volumes may protect against faster decline.Disclosure: Dr. Caunca has nothing to disclose. Dr. Dong has nothing to disclose. Dr. Marquez has nothing to disclose. Dr. Cheung has received personal compensation for activities with Remedy as a consultant. Dr. Cheung has received research support from IBM. Dr. Rundek has nothing to disclose. Dr. Alperin has received personal compensation for activities with Alperin Noninvasive Diagnostics, Inc. Dr. Lee has nothing to disclose. Dr. Bagci has no...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Caunca, M., Dong, C., Marquez, C., Cheung, K., Rundek, T., Alperin, N., Lee, S. L., Bagci, A., Elkind, M., DeCarli, C., Lee, S., Sacco, R., Stern, Y., Wright, C. Tags: Behavioral and Cognitive Neurology Source Type: research

Safety of OnabotulinumtoxinA Treatment With Concomitant Antithrombotic Therapy in Patients With Post-stroke Spasticity: A Pooled Analysis of Randomized, Double-Blind Studies (S56.008)
Conclusions:There is no apparent increased risk of bleeding complications in patients on antithrombotics following IM onabotA treatment; nonetheless, careful observation of the injection site and patient education of the potential for bleeding complications remain warranted.Study Supported by: Allergan plc, Dublin, IrelandDisclosure: Dr. Dimitrova has received personal compensation for activities with Allergan as an employee. Dr. Dimitrova holds stock and/or stock options in Allergan. Dr. James has received personal compensation for activities with Allergan and Chase Pharmaceuticals as an employee. Dr. Liu has received per...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Dimitrova, R., James, L., Liu, C., Orejudos, A., Yushmanova, I., Brin, M. Tags: Movement Disorders: Huntington ' s Disease and Drug-Induced Dyskinesias Source Type: research

Developing a Family of Visual Decision Aids for Intravenous and Endovascular Reperfusion Therapies for Acute Ischemic Stroke (S25.006)
Conclusions:Personograph visual decision aids are a promising approach to rapidly educating patients, family, and healthcare providers on the benefits and risks of the major reperfusion therapies for acute ischemic stroke.Disclosure: Dr. Tokunboh has nothing to disclose. Dr. Vales Montero has nothing to disclose. Dr. Zopelaro has nothing to disclose. Dr. Sharma has nothing to disclose. Dr. Gonzalez has received research support from NIH. Dr. Starkman has received research support from the National Institute of Health, Stryker, Biogen IDEC, Neuravi, Genentech, Covidien, and Astra-Zeneca. Dr. Szeder has nothing to disclose. ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tokunboh, I., Montero, M. V., Zopelaro, M., Sharma, L., Gonzalez, N., Starkman, S., Szeder, V., Jahan, R., Liebeskind, D., Saver, J. Tags: Cerebrovascular Disease and Interventional Neurology: Prehospital and Emergency Department Ischemic Stroke Care Source Type: research

Glucose-regulated protein 78 (GRP78) in plasma and CSF is associated with Parkinsons disease. (S39.008)
Conclusions:Our pilot study suggests that UPR is likely compromised in PD and can be measured in plasma and CSF. With further study, GRP78 may have value as a potential PD biomarker.Study Supported by:This study was made possible by the Clinical and Translational Science Collaborative of Cleveland, UL1TR000439 from the National Center for Advancing Translational Sciences (NCATS) component of the National Institutes of Health and NIH roadmap for Medical Research. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIH.The BioFIND study was sponsored by the Mic...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Gupta, D., Hoppel, C., Goldman, J., Minkler, P., Liu, R., Kerner, J., Tatsuoka, C., Orban, T., Jin, H., Feng, Z. Tags: Movement Disorders: Functional and Structural Imaging in Parkinson ' s Disease Source Type: research

Outcome following hemicraniectomy in children with acute stroke in the International Pediatric Stroke Study (S46.002)
Conclusions:Hemicraniectomy in pediatric stroke is preformed infrequently. Death does occur in these children at a low rate of 5%. The majority of children had moderate to severe deficits. Overall children who have hemicraniectomies continue to have significant neurologic deficits following the procedure. Prospective studies are needed to examine long term morbidity following hemicraniectomy.Disclosure: Dr. Lehman has nothing to disclose. Dr. Dowling has received personal compensation for activities with Neurology Review and Educational Testing Consultants, Inc. Dr. Felling has nothing to disclose. Dr. Chung has nothing to...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Lehman, L., Dowling, M., Felling, R., Chung, M., Pergami, P., Guilliams, K., DeVeber, G., Rivkin, M. Tags: Child Neurology: Molecular Biology to Clinical Trials Source Type: research

A physical sign of stroke sequel on the skeleton of Leonardo da Vinci?
Scholars generally state that Leonardo da Vinci died in 1519 at age 67 of recurrent stroke. One finding may confirm this medical hypothesis: in 1863, the grave of Leonardo was discovered in the Saint-Florentin chapel of Amboise (France), with the skeleton of an old man, tiny fragments of white hair, 8 remaining teeth, and the upper right arm blocked over the skull1 (figure).
Source: Neurology - April 3, 2017 Category: Neurology Authors: Charlier, P., Deo, S. Tags: History of Neurology, Clinical neurology examination, All Cerebrovascular disease/Stroke, Other Education, Forensic neurology NEUROIMAGES Source Type: research

Author response: Influence of sodium consumption and associated knowledge on poststroke hypertension in Uganda
We thank Dr. Chin for the interest and comments on our article.1 We agree that stroke survivors in our study may have received some informal health education, supporting the case for even lower knowledge rates in the public population.1 In Uganda, suboptimal blood pressure control remains a challenge with varied prevalence and excessively low awareness, treatment, and control.2 We agree that the effect of invisible salt in Uganda's urban areas relates to an increasing prevalence of high blood pressure in this population. If not addressed, this portends a high burden of cardiovascular stroke events.3 Because hypertension is...
Source: Neurology - March 12, 2017 Category: Neurology Authors: Kaddumukasa, M. N., Goldstein, L. B. Tags: WRITECLICK & amp;reg; EDITOR ' S CHOICE Source Type: research

Early life risk factors for cerebrovascular disease: A systematic review and meta-analysis
Conclusions: Childhood IQ, SES, and education are associated with increased risk of CVD on neuroimaging in later life. Further studies are required to provide further evidence and thereby inform policy.
Source: Neurology - March 5, 2017 Category: Neurology Authors: Backhouse, E. V., McHutchison, C. A., Cvoro, V., Shenkin, S. D., Wardlaw, J. M. Tags: All Cerebrovascular disease/Stroke, Intelligence, All Education ARTICLE Source Type: research

Neighborhood socioeconomic index and stroke incidence in a national cohort of blacks and whites
Conclusions: Risk of incident stroke increased with decreasing nSES but the effect of nSES is attenuated through individual SES and stroke risk factors. The effect of neighborhood socioeconomic characteristics that contribute to increased stroke risk is similar in black and white participants.
Source: Neurology - November 27, 2016 Category: Neurology Authors: Howard, V. J., McClure, L. A., Kleindorfer, D. O., Cunningham, S. A., Thrift, A. G., Diez Roux, A. V., Howard, G. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Three-dimensional modeling of Eagle syndrome
A 63-year-old man presented with transient episodes of left-hand weakness and right-eye vision loss following a lengthy airplane trip. The patient had reported right neck pain after sleeping awkwardly on the flight. Carotid dissection, paradoxical embolism, atherosclerotic occlusion, and thrombotic occlusion were considered possible etiologies of the associated carotid occlusion. Following a period of anticoagulation, a subsequent CT angiography (figure 1, A–C) revealed findings consistent with the styloid-carotid artery, or Eagle, syndrome.1 A 3-dimensional model was subsequently created (figure 2, A and B) utilizin...
Source: Neurology - November 20, 2016 Category: Neurology Authors: Shah, K., Miller, D. J. Tags: All Headache, All Clinical Neurology, All Cerebrovascular disease/Stroke, All Education NEUROIMAGES Source Type: research

Aerobic exercise and vascular cognitive impairment: A randomized controlled trial
Conclusions: This study provides preliminary evidence for the efficacy of 6 months of thrice-weekly progressive aerobic training in community-dwelling adults with mild SIVCI, relative to usual care plus education. ClinicalTrials.gov identifier: NCT01027858. Classification of evidence: This study provides Class II evidence that for adults with mild SIVCI, an aerobic exercise program for 6 months results in a small, significant improvement in ADAS-Cog performance.
Source: Neurology - November 13, 2016 Category: Neurology Authors: Liu-Ambrose, T., Best, J. R., Davis, J. C., Eng, J. J., Lee, P. E., Jacova, C., Boyd, L. A., Brasher, P. M., Munkacsy, M., Cheung, W., Hsiung, G.-Y. R. Tags: All Cerebrovascular disease/Stroke, Clinical trials Randomized controlled (CONSORT agreement), Vascular dementia, Class I ARTICLE Source Type: research

Emerging Subspecialties in Neurology: Pediatric stroke and cerebrovascular disorders
In 1895, a neuropathologist at the University of Vienna observed that "a large number of cases of infantile cerebral palsy is caused by the same factors that bring about the majority of cases of cerebral paralysis of adults: by tearing, embolism, and thrombosis of cerebral vessels."1 While Sigmund Freud would go on to become better known for other endeavors, his observation that children can have strokes paved the way for the development of the emerging subspecialty of pediatric stroke and cerebrovascular disorders.
Source: Neurology - October 30, 2016 Category: Neurology Authors: Bernson-Leung, M. E., deVeber, G. A. Tags: Childhood stroke, All Cerebrovascular disease/Stroke, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke, All Education RESIDENT AND FELLOW SECTION Source Type: research

Influence of sodium consumption and associated knowledge on poststroke hypertension in Uganda
Conclusions: High urine sodium and high salt-diet preferences were more frequent among poststroke hypertensive patients in Uganda than in their nonhypertensive counterparts. There was, however, no difference in dietary salt knowledge between these groups. The development of educational strategies that include salt-diet preferences may lead to better blood pressure control in this high-risk population.
Source: Neurology - September 18, 2016 Category: Neurology Authors: Kaddumukasa, M. N., Katabira, E., Sajatovic, M., Pundik, S., Kaddumukasa, M., Goldstein, L. B. Tags: All Cerebrovascular disease/Stroke, Case control studies ARTICLE Source Type: research

China's shift from population control to population quality: Implications for neurology
China's population restriction, known across the globe as the 1-child policy, has been in place since 1981, with variations to allow some couples a second child.1,2 In response to social challenges arising from this policy, the Chinese government announced in 2015 that it would transition to a new 2-child policy, encouraging couples since January 1, 2016, to have 2 children.3 This transition accompanies a focus on population quality (i.e., improvements in health, education, and social welfare) in newborns to the large Chinese elderly population, with an initiative to reform the Chinese health care system and increase disea...
Source: Neurology - August 21, 2016 Category: Neurology Authors: Ke, Q., Zhang, L., He, C., Zhao, Z., Qi, M., Griggs, R. C., Gatheridge, M. A. Tags: Stroke prevention, All Neuromuscular Disease, All Cognitive Disorders/Dementia GLOBAL PERSPECTIVES Source Type: research