Hippocampal and white matter hyperintensity volumes are associated with domain-specific cognitive decline: the Northern Manhattan Study (S18.004)

Conclusions:White matter disease burden and gray matter volume predicted decline in cognitive performance over time. Greater hippocampal volumes may protect against faster decline.Disclosure: Dr. Caunca has nothing to disclose. Dr. Dong has nothing to disclose. Dr. Marquez has nothing to disclose. Dr. Cheung has received personal compensation for activities with Remedy as a consultant. Dr. Cheung has received research support from IBM. Dr. Rundek has nothing to disclose. Dr. Alperin has received personal compensation for activities with Alperin Noninvasive Diagnostics, Inc. Dr. Lee has nothing to disclose. Dr. Bagci has nothing to disclose. Dr. Elkind has received personal compensation in an editorial capacity for Neurology. Dr. DeCarli has received personal compensation for activities with Novartis Pharmaceuticals as a consultant. Dr. Lee has received research support from Boehringer Ingelheim. Dr. Sacco has received research support from Boehringer Ingelheim Pharmaceuticals. Dr. Stern has received personal compensation for activities with Takeda, Axovant, and Eli Lilly and Company as an advisor and/or consultant. Dr. Stern has received license fees from Columbia. Dr. Stern has received research support from Axovant, Piramal and the California Walnut Commission. Dr. Wright has received royalty payments from UpToDate.

Source: Neurology - April 17, 2017 Category: Neurology Authors: Caunca, M., Dong, C., Marquez, C., Cheung, K., Rundek, T., Alperin, N., Lee, S. L., Bagci, A., Elkind, M., DeCarli, C., Lee, S., Sacco, R., Stern, Y., Wright, C. Tags: Behavioral and Cognitive Neurology Source Type: research