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Characterization of Parkinson ’s disease using blood-based biomarkers: A multicohort proteomic analysis
ConclusionsIn this study, we found that the blood-based biomarkers BSP, OMD, ACY1, and GHR robustly associated with PD across multiple clinical sites. Our findings suggest that biomarkers based on a peripheral blood sample may be developed for both disease characterization and prediction of future disease progression in PD.
Source: PLoS Medicine - October 10, 2019 Category: Internal Medicine Authors: Marijan Posavi Source Type: research

Depression Is More than a Stigma
Manoj K. Pandey is Lecturer in Economics, Australian National University; Vani S. Kulkarni is Lecturer in Sociology, University of Pennsylvania; and Raghav Gaiha is (Hon. ) Professorial Research Fellow, Global Development Institute, University of ManchesterBy Manoj K. Pandey, Vani S. Kulkarni and Raghav GaihaCanberra, Philadelphia and Manchester, Mar 20 2019 (IPS) Depression is often distinguished from other non-communicable diseases or NCDs (e.g., cancer, diabetes, cardio-vascular diseases, hypertension) because of the stigma attached to it. Among other consequences, those suffering from depression are often denied access...
Source: IPS Inter Press Service - Health - March 20, 2019 Category: International Medicine & Public Health Authors: Manoj K. Pandey - and Raghav Gaiha Tags: Featured Global Headlines Health Human Rights TerraViva United Nations Women's Health Source Type: news

Falling off the health-care radar
Vani S. Kulkarni is a Lecturer in Sociology, University of Pennsylvania, U.S.; Raghav Gaiha is (Hon.) Professorial Research Fellow, Global Development Institute, University of Manchester, U.K.By Vani S. Kulkarni and Raghav GaihaPHILADELPHIA and NEW DELHI, Sep 28 2017 (IPS)Care for the elderly needs to be better targeted by the health system and social networks. The National Health Policy (NHP), 2017 is unable to see the wood for the trees. Life and death questions are dealt with perfunctorily or simply overlooked. For example, it overlooks the rapid rise in the share of the old (60 years or more), and associated morbiditie...
Source: IPS Inter Press Service - Health - September 28, 2017 Category: International Medicine & Public Health Authors: S Kulkami Tags: Aid Asia-Pacific Headlines Health Human Rights TerraViva United Nations Source Type: news

Care for the elderly needs to be better targeted by the health system and social networks
Vani S. Kulkarni is a Lecturer in Sociology, University of Pennsylvania, U.S.; Raghav Gaiha is (Hon.) Professorial Research Fellow, Global Development Institute, University of Manchester, U.K.By Vani S. Kulkarni and Raghav GaihaPHILADELPHIA and NEW DELHI, Sep 28 2017 (IPS)The National Health Policy (NHP), 2017 is unable to see the wood for the trees. Life and death questions are dealt with perfunctorily or simply overlooked. For example, it overlooks the rapid rise in the share of the old (60 years or more), and associated morbidities, especially sharply rising non-communicable diseases (NCDs) and disabilities. With rising...
Source: IPS Inter Press Service - Health - September 28, 2017 Category: International Medicine & Public Health Authors: S Kulkami Tags: Aid Asia-Pacific Headlines Health Human Rights Source Type: news

Long-term Outcomes of Parkinson's Disease Patients with Normal Cognition. (P5.260)
Conclusion:More than one-third of PD patients with NC develop cognitive impairment within 4 years, and the majority of new MCI cases convert to dementia within 3 years. Worse executive, language and memory abilities all predict future decline. These results are consistent with previous studies reporting that the overwhelming majority of PD patients develop cognitive impairment long-term, and have implications for understanding disease course and clinical care.Disclosure: Dr. Pigott has nothing to disclose. Dr. Rick has nothing to disclose. Dr. Hurtig has nothing to disclose. Dr. Chen-Plotkin has received research support f...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Pigott, K., Rick, J., Hurtig, H., Chen-Plotkin, A., Duda, J., Morley, J., Chahine, L., Dahodwala, N., Fleisher, J., Akhtar, R., Siderowf, A., Goldmann Gross, R., Xie, S., Trojanowski, J., Weintraub, D. Tags: Movement Disorders: Cognition and Parkinson ' s Disease Source Type: research

Neuropsychologic assessment in collaborative Parkinson’s disease research: A proposal from the National Institute of Neurological Disorders and Stroke Morris K. Udall Centers of Excellence for Parkinson’s Disease Research at the University of Pennsylvania and the University of Washington
Abstract: Cognitive impairment (CI) and behavioral disturbances can be the earliest symptoms of Parkinson's disease (PD), ultimately afflict the vast majority of PD patients, and increase caregiver burden. Our two Morris K. Udall Centers of Excellence for Parkinson's Disease Research were supported by the National Institute of Neurological Disorders and Stroke (NINDS) in an effort to recommend a comprehensive yet practical approach to cognitive and behavioral assessment to further collaborative research. We recommend a stepwise approach with two levels of standardized evaluation to establish a common battery, as well as an...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 19, 2012 Category: Geriatrics Authors: G. Stennis Watson, Brenna A. Cholerton, Rachel G. Gross, Daniel Weintraub, Cyrus P. Zabetian, John Q. Trojanowski, Thomas J. Montine, Andrew Siderowf, James B. Leverenz Tags: Perspectives Source Type: research