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Testosterone and cardiac mass and function in men with type 1 diabetes in the Epidemiology of Diabetes Interventions and Complications Study (EDIC)
ConclusionsAmong men with type 1 diabetes, higher total testosterone was associated with higher LV mass and volume but not with function. The clinical significance of this association remains to be established.This article is protected by copyright. All rights reserved.
Source: Clinical Endocrinology - December 7, 2015 Category: Endocrinology Authors: Catherine Kim, Ionut Bebu, Barbara Braffett, Patricia A. Cleary, Valerie Arends, Michael Steffes, Hunter Wessells, Trevor Orchard, Aruna V. Sarma, Tags: Original Article Source Type: research

Obesity, Insulin Resistance, and Incident Small Vessel Disease on Magnetic Resonance Imaging: Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— The IR score and central obesity are associated with incident lacunar disease but not WMH progression in individuals. Central obesity and IR may be important risk factors to target to prevent lacunar disease.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Dearborn, J. L., Schneider, A. L. C., Sharrett, A. R., Mosley, T. H., Bezerra, D. C., Knopman, D. S., Selvin, E., Jack, C. R., Coker, L. H., Alonso, A., Wagenknecht, L. E., Windham, B. G., Gottesman, R. F. Tags: Glucose intolerance, CT and MRI, Cerebral Lacunes, Epidemiology Clinical Sciences Source Type: research

Hemichorea in a diabetes mellitus patient following acute ischemic stroke with changes in regional cerebral blood flow
Publication date: Available online 4 March 2015 Source:Journal of the Chinese Medical Association Author(s): Yutaka Suzuki , Minoru Oishi , Akira Kanno , Katsuhiko Ogawa , Mariko Fujisawa , Satoshi Kamei It is not unusual to observe hemichorea in patients with diabetes mellitus, with origins attributable to recent ischemia. Our patient was a 66-year-old female with diabetes mellitus who suddenly developed right hemichorea, mild muscle weakness of the right upper extremity, ideational apraxia, and acalculia. Her blood glucose was 600 mg/dL, and HbA1c was 13.3%. After the patient underwent head magnetic resonance imaging ...
Source: Journal of the Chinese Medical Association - March 4, 2015 Category: Journals (General) Source Type: research

Imaging of a Clinically Relevant Stroke Model: Glucose Hypermetabolism Revisited Basic Sciences
Conclusions— The increased uptake of [2-18F]-2-fluoro-2-deoxy-d-glucose in cerebral ischemia most likely reflects hypermetabolism of glucose meeting increased energy needs of ischemic and hypoperfused brain tissue, and it occurs under both anaerobic and aerobic conditions measured by local lactate production. Infarct-related systemic hyperglycemia could serve to facilitate glucose supply to the ischemic brain. Glycemic control by insulin treatment could negatively influence this mechanism.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Arnberg, F., Grafstrom, J., Lundberg, J., Nikkhou-Aski, S., Little, P., Damberg, P., Mitsios, N., Mulder, J., Lu, L., Soderman, M., Stone-Elander, S., Holmin, S. Tags: Acute Stroke Syndromes, Brain Circulation and Metabolism Basic Sciences Source Type: research

Higher C‐peptide levels are associated with regional cortical thinning in 1093 cognitively normal subjects
ConclusionsA higher C‐peptide level is associated with regional cortical thinning, even in cognitively normal individuals.
Source: European Journal of Neurology - July 3, 2014 Category: Neurology Authors: C. W. Yoon, M. Kang, H. Y. Shin, S. Jeon, J.‐J. Yang, S. T. Kim, Y. Noh, G. H. Kim, H. J. Kim, Y. J. Kim, J.‐H. Kim, H. Cho, B. S. Ye, J. M. Lee, S. H. Choi, K. Im, H.‐S. Moon, D. L. Na, S. W. Seo Tags: Original Article Source Type: research

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