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Amoxicillin/clavulanic acid-associated severe neutropenia
A 72-year-old man presented with an abnormal blood count and was admitted. His history included hypertension and hyperlipidaemia with an old myocardial infarction and mild stroke; liver cirrhosis due to non-alcoholic steatohepatitis (NASH) with hypersplenism and oesophageal varices but no ascites, oedema or bleeding; and benign prostatic hypertrophy. His medications (unchanged for years) included furosemide, spironolactone, bisoprolol, rosuvastatin, alfuzosin and omeprazole. Two weeks prior, he was discharged from our department after left leg cellulitis and Streptococcus pyogenes bacteraemia responsive to parenteral clind...
Source: Postgraduate Medical Journal - March 22, 2022 Category: General Medicine Authors: Schattner, A., Dubin, I. Tags: Adverse drug reactions Source Type: research

En kvinne i 50- årene med residiverende svimmelhet.
En kvinne i 50-årene med residiverende svimmelhet. Tidsskr Nor Laegeforen. 2020 Aug 18;140(11): Authors: Eriksen E, Smebye KL, Mejlænder-Evjensvold M, Sandset EC Abstract BACKGROUND: Vasculitis caused by neuroborreliosis is one of many rare described causes of stroke. CASE PRESENTATION: A female smoker in her fifties presented with dizziness due to a left cerebellar infarction, and after general stroke workup atherosclerosis was considered the probable cause. In the preceding months she had experienced nonspecific intermittent headache, neck pain and dizziness initially attributed to prior head...
Source: Tidsskrift for den Norske Laegeforening - August 17, 2020 Category: General Medicine Authors: Eriksen E, Smebye KL, Mejlænder-Evjensvold M, Sandset EC Tags: Tidsskr Nor Laegeforen Source Type: research

Repeated episodes of acute stroke as manifestation of neurosyphilis in a well-controlled human immunodeficiency virus-infected patient —Successful treatment with ceftriaxone
Publication date: Available online 9 February 2017 Source:Journal of the Formosan Medical Association Author(s): Tsung-Chia Chen, Jen-Hsien Wang, Tzung-Chang Tsai
Source: Journal of the Formosan Medical Association - February 9, 2017 Category: Journals (General) Source Type: research

Repeated episodes of acute stroke as manifestation of neurosyphilis in a well-controlled human immunodeficiency virus-infected patient-Successful treatment with ceftriaxone.
PMID: 28190667 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - February 8, 2017 Category: Journals (General) Authors: Chen TC, Wang JH, Tsai TC Tags: J Formos Med Assoc Source Type: research

Correspondence Parenteral antibiotics are not enough to prevent pneumonia in stroke
The Preventive Antibiotics in Stroke Study (PASS; April 18, p 1519)1 reported that parenteral ceftriaxone did not significantly reduce pneumonia. We would like to comment on these results.
Source: LANCET - August 14, 2015 Category: Journals (General) Authors: Luciano Silvestri, Hendrick K F van Saene, Marco Milanese, Silvia Ros, Durk F Zandstra Tags: Correspondence Source Type: research

The Preventive Antibiotics in Stroke Study (PASS): a pragmatic randomised open-label masked endpoint clinical trial
Publication date: Available online 20 January 2015 Source:The Lancet Author(s): Willeke F Westendorp , Jan-Dirk Vermeij , Elles Zock , Imke J Hooijenga , Nyika D Kruyt , Hans J L W Bosboom , Vincent I H Kwa , Martijn Weisfelt , Michel J M Remmers , Robert ten Houten , A H C M (Tobien) Schreuder , Sarah E Vermeer , Ewout J van Dijk , Diederik W J Dippel , Marcel G W Dijkgraaf , Lodewijk Spanjaard , Marinus Vermeulen , Tom van der Poll , Jan M Prins , Frederique H Vermeij , Yvo B W E M Roos , Ruud P Kleyweg , Henk Kerkhoff , Matthijs C Brouwer , Aeilko H Zwinderman , Diederik van de Beek , Paul J Nederkoorn Background In a...
Source: The Lancet - January 21, 2015 Category: Journals (General) Source Type: research

Articles The Preventive Antibiotics in Stroke Study (PASS): a pragmatic randomised open-label masked endpoint clinical trial
Preventive ceftriaxone does not improve functional outcome at 3 months in adults with acute stroke. The results of our trial do not support the use of preventive antibiotics in adults with acute stroke.
Source: LANCET - January 20, 2015 Category: Journals (General) Authors: Willeke F Westendorp, Jan-Dirk Vermeij, Elles Zock, Imke J Hooijenga, Nyika D Kruyt, Hans J L W Bosboom, Vincent I H Kwa, Martijn Weisfelt, Michel J M Remmers, Robert ten Houten, A H C M (Tobien) Schreuder, Sarah E Vermeer, Ewout J van Dijk, Diederik W J Tags: Articles Source Type: research

Update of the Preventive Antibiotics in Stroke Study (PASS): statistical analysis plan
Conclusions: The data from PASS will establish whether preventive antibiotic therapy in acute stroke improves functional outcome by preventing infection and will be analyzed according to this pre-specified SAP.Trial registration: Current controlled trials; ISRCTN66140176. Date of registration: 6 April 2010.
Source: Trials - October 1, 2014 Category: Journals (General) Authors: Willeke WestendorpJan-Dirk VermeijDiederik DippelMarcel DijkgraafTom van der PollJan PrinsFrederique VermeijYvo RoosMatthijs BrouwerAeilko ZwindermanDiederik van de BeekPaul Nederkoorn Source Type: research