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Drug: Methylprednisolone
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Total 253 results found since Jan 2013.
Clinicohistological Profile and Outcomes of Rapidly Progressive Glomerulonephritis: A Prospective Study from North India
This study included 40 patients of biopsy-proven RPGN. The diagnosis of RPGN was based on renal histology showing crescents in >50% of glomeruli. All patients were given induction with intravenous (IV) methylprednisolone (0.5 g) for three days followed by maintenance with oral prednisolone (1 mg/kg/day) and six IV pulses of cyclophosphamide (0.5 g) given fortnightly followed by maintenance therapy with azathioprine (2 mg/kg/day). The outcomes were recorded. Three-fourth of the patients (77.4%) required renal replacement therapy (RRT) at diagnosis. More than half of patients (57.5%) were antineutrophil cytoplasmic antibo...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Deepak Sharma Sudhir Mehta Jasvinder Singh Sandhu Preet Mohinder Sohal Vikas Makkar Source Type: research
Stroke-like presentation of autoimmune chorea with positive anti-Yo and anti-MOG antibodies: a case report
AbstractWith the in-depth study of autoimmune encephalitis, more and more antibody combinations and clinical manifestations appear in our sights, enriching the spectrum of autoimmune encephalitis. Here, we report a case of a 58-year-old male patient with sudden involuntary movement of the left limb. The brain MRI was normal. CSF analysis showed slightly elevated protein (548.38 mg/L) and normal cell count(1.00 10^6/L). No tumors were detected by the whole-body PET-CT. Positive anti-Yo and anti-MOG antibodies were found in the blood. So we considered the diagnosis of autoimmune chorea with positive anti-Yo and anti-MOG a...
Source: Neurological Sciences - October 25, 2022 Category: Neurology Source Type: research
Aseptic meningitis in Fabry disease due to a novel GLA variant: an expanded phenotype?
ConclusionWe described aseptic meningitis in a family with a novelGLA variant. Meningitis might be a common phenomenon in FD and not a particularity of this variant. Understanding the mechanisms underlying meningitis and its association with cerebrovascular events may lead to a new paradigm of treatment for stroke in these patients. Further prospective studies with CSF collection in patients with FD and recurrent headache could help to elucidate this question.
Source: Neurological Sciences - September 12, 2022 Category: Neurology Source Type: research
Predicting the response to methylprednisolone pulses in patients with SARS-COV-2 infection
CONCLUSIONS: In patients with methylprednisolone pulses, the capacity of the predictive model for hospital discharge including variables collected at 5 days was (area under the curve) 0.816.PMID:35718548 | DOI:10.1016/j.medcli.2022.02.025
Source: Medicina Clinica - June 19, 2022 Category: General Medicine Authors: Antonio J Sarri á-Landete Jos é A Crespo-Matas Inmaculada Dom ínguez-Quesada Jes ús J Castellanos-Monedero Din és Marte-Acosta Ángel J Arias-Arias Source Type: research
