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Internal carotid artery and bilateral vertebral arteries dissections associated with amphetamine abuse: Case report
We reported the Case of a 40-year-old male patient with chronic amphetamine used since childhood. He had increased the consumption from once a month to every other day in the last year. The patient suffered from acute left-side hemiparesis and neglect. Computed tomography angiography of the brain and neck vessels demonstrated non-atheromatous vasculopathy with a suspected dissection process of the right internal carotid artery and bilateral vertebral arteries. A review of recent data is also provided to clarify the possible mechanism.PMID:34401140 | PMC:PMC8353386 | DOI:10.1016/j.amsu.2021.102676
Source: Annals of Medicine - August 17, 2021 Category: Internal Medicine Authors: Nopdanai Sirimaharaj Kitti Thiankhaw Source Type: research

Intracerebral Hemorrhage Associated with Oral Phenylephrine Use: A Case Report and Review of the Literature
Conclusions: It is scientifically plausible that phenylephrine may cause strokes, consistent with the pharmacologic properties and adverse event profiles of similar amphetamine-like sympathomimetics. As RCVS has been well described in association with over-the-counter sympathomimetics, a likely, although not definitive, causal relationship between phenylephrine and ICH is proposed.
Source: Journal of Stroke and Cerebrovascular Diseases - August 25, 2014 Category: Neurology Authors: Brian E. Tark, Steven R. Messe, Clotilde Balucani, Steven R. Levine Tags: Original Articles Source Type: research

Intracerebral Hemorrhage Associated with Oral Phenylephrine Use (P5.138)
CONCLUSION: It is scientifically plausible that Phe may cause strokes given that it is consistent with the pharmacological properties and adverse event profiles of similar amphetamine-like sympathomimetics. As RCVS has been well-described in association with over the counter sympathomimetics, these lines of evidence support a likely, although not definitive, causal relationship between Phe and ICH.Disclosure: Dr. Tark has nothing to disclose. Dr. Messe has received personal compensation for activities with GlaxoSmithKline, Inc. Dr. Messe has received research support from WL Gore, and GlaxoSmithKline, Inc. Dr. Balucani has...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Tark, B., Messe, S., Balucani, C., Levine, S. Tags: Cerebrovascular Disease and Interventional Neurology: Intracerebral Hemorrhage and Other Hemorrhages Source Type: research