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Specialty: Cardiology
Countries: Netherlands Health

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Total 103 results found since Jan 2013.

Safety and efficacy of balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension in the Netherlands.
CONCLUSIONS: BPA performed in a CTEPH expert centre is an effective and safe treatment in patients with inoperable CTEPH. PMID: 31782109 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - November 27, 2019 Category: Cardiology Authors: van Thor MCJ, Lely RJ, Braams NJ, Ten Klooster L, Beijk MAM, Heijmen RH, van den Heuvel DAF, Rensing BJWM, Snijder RJ, Vonk Noordegraaf A, Nossent EJ, Meijboom LJ, Symersky P, Mager JJ, Bogaard HJ, Post MC Tags: Neth Heart J Source Type: research

Management and outcomes of real-world use of non-vitamin-K oral anticoagulants (NOACs) in patients with atrial fibrillation: experience of a  dedicated NOAC clinic.
CONCLUSIONS: We observed low rates of bleeding and adverse drug reactions. However, rates of mortality and discontinuation were relatively high. These results could possibly be explained by the real-world nature of the data including higher-risk patients. PMID: 31773474 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - November 25, 2019 Category: Cardiology Authors: de Veer AJWM, Bennaghmouch N, Wijffels MCEF, Ten Berg JM Tags: Neth Heart J Source Type: research

First report of a  comparative patient-oriented perspective on the use of non-vitamin-K oral anticoagulants or vitamin-K antagonists in atrial fibrillation: patients' experiences, side-effects and practical problems leading to non-adherence.
CONCLUSION: Patient experiences support the current guideline recommendations for NOACs as the first-choice therapy: NOAC therapy resulted in a higher practical feasibility and better adherence when compared with VKA therapy, with a similar incidence of adverse events in both groups. PMID: 31745815 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - November 18, 2019 Category: Cardiology Authors: Bennaghmouch N, de Veer AJWM, Zivelonghi C, van Dijk L, Ten Berg JM Tags: Neth Heart J Source Type: research

Design and rationale of ischaemia-driven complete revascularisation versus usual care in patients with non-ST-elevation myocardial infarction and multivessel coronary disease: the South Limburg Myocardial Infarction (SLIM) trial.
CONCLUSION: The SLIM trial aims to provide evidence whether FFR-guided complete revascularisation by PCI is superior to usual care with respect to clinical outcomes (major adverse cardiovascular events) in non-STEMI patients with MVD. PMID: 31531823 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - September 16, 2019 Category: Cardiology Authors: Pustjens TFS, Streukens B, Vainer J, Gho B, Ruiters AW, Stein M, Ilhan M, Veenstra L, Theunissen R, Bekkers SCAM, Van't Hof AWJ, Rasoul S Tags: Neth Heart J Source Type: research

Left atrial appendage closure in atrial fibrillation patients with prior major bleeding or ineligible for oral anticoagulation.
CONCLUSIONS: Percutaneous LAAC may provide an alternative strategy to long-term OAC therapy in AF patients with a high bleeding risk. During follow-up, both ischaemic stroke and recurrent bleeding rates were lower than expected based on the CHA2DS2-VASc and HAS-BLED scores respectively. PMID: 31187455 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - June 10, 2019 Category: Cardiology Authors: Wintgens LIS, Vorselaars VMM, Klaver MN, Swaans MJ, Alipour A, Rensing BJWM, Post MC, Boersma LVA Tags: Neth Heart J Source Type: research

Young Stroke Survivors Face Increased Long-Term Death Risk Young Stroke Survivors Face Increased Long-Term Death Risk
A national Dutch study in more than 15,000 adults younger than 50 who survived at least 30 days following a first stroke suggests higher mortality risks over time for these patients.Medscape Medical News
Source: Medscape Cardiology Headlines - May 29, 2019 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Idiopathic atrial fibrillation patients rapidly outgrow their low thromboembolic risk: a  10-year follow-up study.
CONCLUSION: The majority of recently diagnosed healthy AF patients develop cardiovascular diseases with a consequent change in thromboembolic risk profile within a short time frame. A comprehensive follow-up of this patient category is necessary to avoid over- and undertreatment with anticoagulants. PMID: 30953281 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - April 4, 2019 Category: Cardiology Authors: Weijs B, Dudink EAMP, de Vos CB, Limantoro I, Tieleman RG, Pisters R, Cheriex EC, Luermans JGLM, Crijns HJGM Tags: Neth Heart J Source Type: research

Inappropriate non-vitamin  K antagonist oral anticoagulants prescriptions: be cautious with dose reductions.
CONCLUSION: An incorrect prescription occurred more often in the reduced-dose NOAC group. Clinical parameters such as renal function are often unknown whilst these are essential to determine the right NOAC and dose. PMID: 30949972 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - April 3, 2019 Category: Cardiology Authors: Jacobs MS, van Hulst M, Campmans Z, Tieleman RG Tags: Neth Heart J Source Type: research

Frailty score for elderly patients is associated with short-term clinical outcomes in patients with ST-segment elevated myocardial infarction treated with primary percutaneous coronary intervention.
CONCLUSIONS: VMS score for frailty is independently associated with short-term mortality and PCI-related SAE in elderly patients with STEMI treated with primary PCI. These results suggest that frailty in elderly patients is an important feature to measure and to be taken into account when developing risk models. PMID: 30771094 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - February 15, 2019 Category: Cardiology Authors: Hermans MPJ, Eindhoven DC, van Winden LAM, de Grooth GJ, Blauw GJ, Muller M, Schalij MJ Tags: Neth Heart J Source Type: research

Hemodynamics of paradoxical severe aortic stenosis: insight from a pressure –volume loop analysis
ConclusionsThe present study suggests that the hemodynamics of PLFLG AS can be explained by two mechanisms: (1) stiffness of the small left ventricle with reduced contractility, and (2) increased afterload due to the impairment of vascular function. Both mechanisms have similarities to those of heart failure with preserved EF. This type of remodeling may explain the poor prognosis of PLFLG AS.
Source: Clinical Research in Cardiology - February 8, 2019 Category: Cardiology Source Type: research

Design and rationale of the Edoxaban Treatment in routiNe clinical prActice for patients with Atrial Fibrillation in Europe (ETNA-AF-Europe) study
This study details the design of the Edoxaban Treatment in routiNe clinical prActice for patients with Atrial Fibrillation in Europe (ETNA-AF-Europe) study – a postauthorization observational study, which is part of the postapproval plan for edoxaban agreed with the European Medicines Agency. Methods The ETNA-AF-Europe study (Clinicaltrials.gov: NCT02944019) is a multicenter, prospective, observational study that enrolled 13 980 patients with atrial fibrillation treated with edoxaban from 852 sites across 10 European countries (Austria, Belgium, Germany, Ireland, Italy, the Netherlands, Portugal, Spain, Switzerland,...
Source: Journal of Cardiovascular Medicine - January 3, 2019 Category: Cardiology Tags: Research articles: Trial design Source Type: research

Red blood cell transfusion in patients with ST-elevation myocardial infarction-a  meta-analysis of more than 21,000 patients.
CONCLUSIONS: Red blood cell transfusion increases the morbidity and mortality in patients with STEMI. This difference could not be explained by the higher morbidity in the red blood cell transfusion group alone. Further randomised controlled trials are required to provide a reliable haemoglobin threshold for these patients. PMID: 30039381 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - July 23, 2018 Category: Cardiology Authors: Mincu RI, Rassaf T, Totzeck M Tags: Neth Heart J Source Type: research

Trends in patient characteristics and clinical outcome over 8  years of transcatheter aortic valve implantation.
CONCLUSION: A clear shift towards a lower-risk TAVI population and improved clinical outcome was observed over an 8‑year period. Survival after TAVI improved impressively, mainly as a consequence of decreased 30-day mortality. PMID: 29943117 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - June 25, 2018 Category: Cardiology Authors: van Kesteren F, van Mourik MS, Wiegerinck EMA, Vendrik J, Piek JJ, Tijssen JG, Koch KT, Henriques JPS, Wykrzykowska JJ, de Winter RJ, Driessen AHG, Kaya A, Planken RN, Vis MM, Baan J Tags: Neth Heart J Source Type: research

One-year efficacy and safety of routine prasugrel in patients with acute coronary syndromes treated with percutaneous coronary intervention: results of the prospective rijnmond collective cardiology research study.
CONCLUSIONS: In routine practice, a tailored approach of prasugrel prescription in ACS patients undergoing PCI, resulted in low ischaemic and low bleeding rates up to 1 year post PCI. PMID: 29931649 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - June 21, 2018 Category: Cardiology Authors: Yetgin T, Boersma E, Smits PC, de Vries AG, Huijskens E, Zijlstra F, van der Linden MMJM, van Geuns RJM, CCR Study Investigators Tags: Neth Heart J Source Type: research

Optimal antithrombotic treatment of patients with atrial fibrillation undergoing percutaneous coronary intervention: triple therapy is too much!
Abstract Patients with atrial fibrillation who undergo a coronary intervention are eligible for both anticoagulation and (dual) antiplatelet therapy ((D)APT). An optimal balance has to be found to reduce the thromboembolic risk (i.e. stroke, systemic embolism and myocardial infarction) and to minimise the increased risk of bleeding with concomitant use of an anticoagulant and (D)APT. Owing to a lack of evidence, the guideline recommendations are predominantly based on expert opinion. Current evidence indicates that the combination of a non-vitamin K oral anticoagulant (NOAC) and clopidogrel is safer than vitam...
Source: Netherlands Heart Journal - May 8, 2018 Category: Cardiology Authors: Jacobs MS, Tieleman RG Tags: Neth Heart J Source Type: research