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Twenty four hours hypothermia has temporary efficacy in reducing brain infarction and inflammation in aged rats
Stroke is a major cause of disability for which no neuroprotective measures are available. Age is the principal nonmodifiable risk factor for this disease. Previously, we reported that exposure to hydrogen sulfide (H2S) for 48 hours post-stroke lowers whole body temperature and confers neuroprotection in aged animals. Since the duration of hypothermia in most clinical trials is between 24 and 48 hrs, we questioned whether 24 hr exposure to gaseous hypothermia confers the same neuroprotective efficacy as 48 hr exposure.
Source: Neurobiology of Aging - November 19, 2015 Category: Neuroscience Authors: Raluca Elena Sandu, Ana-Maria Buga, Adrian Tudor Balseanu, Mihai Moldovan, Aurel Popa-Wagner Source Type: research

Low-frequency rTMS in patients with subacute ischemic stroke: clinical evaluation of short and long-term outcomes and neurophysiological assessment of cortical excitability.
This study is the first to measure the dynamics of cortical excitability by TMS mapping before and after treatment with low-frequency (LF) rTMS in the contralesional hemisphere at three different timepoints. Furthermore, the patients were clinically evaluated during the same visit as the mapping to establish both short and long-term outcomes after rTMS treatment. METHODS AND RESULTS: A total of 16 participants with acute ischemic stroke were assessed 10 days post-stroke by TMS mapping. The patients were randomized into two equal groups: a real rTMS group and a sham group. The rTMS group received LF-rTMS to the contrale...
Source: Journal of Medicine and Life - November 18, 2015 Category: Journals (General) Tags: J Med Life Source Type: research

Adiponectin predicts cardiovascular events in diabetes dialysis patients.
CONCLUSIONS: In diabetes dialysis patients low adiponectin favors occurrence of atherosclerosis related cardiovascular events. PMID: 26006757 [PubMed - as supplied by publisher]
Source: Clinical Biochemistry - May 22, 2015 Category: Biochemistry Authors: Kacso IM, Potra AR, Bondor CI, Moldovan D, Rusu C, Patiu IM, Racasan S, Orasan R, Vladutiu D, Spanu C, Rusu A, Nita C, Moldovan R, Ghigolea B, Kacso G Tags: Clin Biochem Source Type: research

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