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Higher habitual dietary intakes of flavanols and anthocyanins differentially associate with lower incidence of ischemic stroke subtypes-A follow-up analysis
CONCLUSIONS: Higher habitual intakes of flavanols and anthocyanins are differentially associated with lower risk of ischemic stroke from atherosclerosis and/or cardioembolism, but not with other subtypes.PMID:37716608 | DOI:10.1016/j.tjnut.2023.09.011
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Benjamin H Parmenter Pratik Pokharel Frederik Dalgaard Kevin Murray Aed ín Cassidy Catherine P Bondonno Joshua R Lewis Cecilie Kyr ø Anne Tj ønneland Kim Overvad Jonathan M Hodgson Nicola P Bondonno Source Type: research

Trends in low-density lipoprotein cholesterol goal achievement and changes in lipid-lowering therapy after incident atherosclerotic cardiovascular disease: Danish cohort study
CONCLUSION: LDL-C goal achievement within the first 2 years after inclusion increased from 40.5% in 2010 to 50.6% in 2015. LLT initiation within the first year after inclusion increased, especially for intensive LLT, although only one third initiated intensive LLT in 2015. Despite trends show improvements in LDL-C goal achievement, 49.4% of individuals at very high risk of a CV event did not achieve the LDL-C goal within 2 years after ASCVD hospitalization.PMID:37256879 | PMC:PMC10231813 | DOI:10.1371/journal.pone.0286376
Source: Atherosclerosis - May 31, 2023 Category: Cardiology Authors: Annette Kj ær Ersbøll Marie Skov Kristensen Mads Nybo Simone M øller Hede Kristian Handberg Mikkelsen Gunnar Gislason Mogens Lytken Larsen Anders Green Source Type: research

Dual elevated remnant cholesterol and C-reactive protein in myocardial infarction, atherosclerotic cardiovascular disease, and mortality
CONCLUSIONS: Dual elevated remnant cholesterol and C-reactive protein confers the highest risk of myocardial infarction, ASCVD, and all-cause mortality, that is, compared to either of these two factors individually.PMID:37217436 | DOI:10.1016/j.atherosclerosis.2023.05.010
Source: Atherosclerosis - May 22, 2023 Category: Cardiology Authors: Takahito Doi Anne Langsted B ørge G Nordestgaard Source Type: research

The Rationalisation of Intra-Operative Imaging During Cardiac Surgery: A Systematic Review
CONCLUSION: Current data have shown EUS to have superiority over manual palpation and transoesophageal echocardiography in the prevention of CVAs following cardiac surgery. Yet, EUS has not been implemented as a routine standard of care. Extensive adoption of EUS in clinical practice is warranted to aid large, randomised trials before making prospective conclusions on the efficacy of this screening method.PMID:36870922 | DOI:10.1016/j.hlc.2023.01.016
Source: Atherosclerosis - March 4, 2023 Category: Cardiology Authors: Mona Jaffar-Karballai Fatima Kayali Bianca Botezatu Danish Iltaf Satti Amer Harky Source Type: research

Low-Density Lipoprotein Cholesterol Is Predominantly Associated With Atherosclerotic Cardiovascular Disease Events in Patients With Evidence of Coronary Atherosclerosis: The Western Denmark Heart Registry
CONCLUSIONS: LDL-C appears to be almost exclusively associated with ASCVD events over ≈5 years of follow-up in middle-aged individuals with versus without evidence of coronary atherosclerosis. This information is valuable for individualized risk assessment among middle-aged people with or without coronary atherosclerosis.PMID:36621817 | DOI:10.1161/CIRCULATIONAHA.122.061010
Source: Atherosclerosis - January 9, 2023 Category: Cardiology Authors: Martin B ødtker Mortensen Omar Dzaye Hans Erik B øtker Jesper M øller Jensen Michael Maeng Jacob Fog Bentzen Helle Kanstrup Henrik Toft S ørensen Jonathon Leipsic Ron Blankstein Khurram Nasir Michael J Blaha Bjarne Linde N ørgaard Source Type: research

Intake of marine and plant-derived n-3 fatty acids and development of atherosclerotic cardiovascular disease in the Danish Diet, Cancer and Health cohort
CONCLUSIONS: A high intake of marine n-3 PUFA was associated with a lower risk of total ASCVD and acute major ischemic events, whereas no association could be demonstrated for the plant-derived ALA.PMID:36592188 | DOI:10.1007/s00394-022-03081-w
Source: Atherosclerosis - January 2, 2023 Category: Cardiology Authors: Christian S Bork S øren Lundbye-Christensen Stine K Ven ø Anne N Lasota Anne Tj ønneland Erik B Schmidt Kim Overvad Source Type: research

Similarities and differences in systemic risk factors for retinal artery occlusion and retinal vein occlusion: A nationwide case-control study
CONCLUSION: Differences in the level of associations with the included risk factors suggests differences in the pathophysiologies of the two diseases. The main pathophysiology associated with RAO was atherosclerosis, whereas the main pathophysiology associated with RVO was changes in the pressure gradients of the eyes.PMID:36056288 | DOI:10.1007/s10792-022-02483-3
Source: Atherosclerosis - September 2, 2022 Category: Cardiology Authors: Marie Ørskov Henrik Vorum Torben Bjerregaard Larsen Gregory Y H Lip Toke Bek Flemming Skj øth Source Type: research

Clinical risk factors for retinal artery occlusions: a nationwide case-control study
CONCLUSION: The investigated risk factors suggest that atherosclerosis and conditions changing the intraocular pressure are involved in the pathophysiology of RAO.PMID:35305540 | DOI:10.1007/s10792-022-02247-z
Source: Atherosclerosis - March 19, 2022 Category: Cardiology Authors: Marie Ørskov Henrik Vorum Torben Bjerregaard Larsen Gregory Y H Lip Toke Bek Flemming Skj øth Source Type: research

Association of Coronary Plaque With Low-Density Lipoprotein Cholesterol Levels and Rates of Cardiovascular Disease Events Among Symptomatic Adults
CONCLUSIONS AND RELEVANCE: The findings of this cohort study suggest that in symptomatic patients with severely elevated LDL-C levels of at least 190 mg/dL who are universally considered to be at high risk by guidelines, absence of calcified and noncalcified plaque on coronary computed tomographic angiography was associated with low risk for ASCVD events. These results further suggest that atherosclerosis burden, including CAC, can be used to individualize treatment intensity in patients with severely elevated LDL-C levels.PMID:35147685 | DOI:10.1001/jamanetworkopen.2021.48139
Source: Atherosclerosis - February 11, 2022 Category: Cardiology Authors: Martin B ødtker Mortensen Miguel Ca ínzos-Achirica Flemming Hald Steffensen Hans Erik B øtker Jesper M øller Jensen Niels Peter R ønnow Sand Michael Maeng Jens Meldgaard Bruun Michael J Blaha Henrik Toft S ørensen Manan Pareek Khurram Nasir Bjarne L Source Type: research