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Specialty: Cardiology
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Total 500 results found since Jan 2013.

Elevated hs-CRP and Symptomatic Intracranial/Extracranial Artery Stenosis Predict Stroke Recurrence after Acute Ischemic Stroke or TIA
CONCLUSION: Symptomatic intracranial or extracranial artery stenosis was associated with increased risk of recurrent ischemic stroke, stroke, and CVE at 1 year in patients with AIS or TIA, especially in patients with elevated hs-CRP levels. Asymptomatic intracranial or extracranial artery stenosis did not increase the risk of ischemic events compared with no artery stenosis regardless of hs-CRP levels.PMID:35934783 | DOI:10.5551/jat.63512
Source: Journal of Atherosclerosis and Thrombosis - August 7, 2022 Category: Cardiology Authors: Shiyu Li Jing Jing Jiejie Li Anxin Wang Xia Meng Yongjun Wang Source Type: research

Association of immunoglobulin G N-glycosylation with carotid atherosclerotic plaque phenotypes and actual clinical cardiovascular events: a study protocol for a longitudinal prospective cohort study
BMJ Open. 2022 Jul 22;12(7):e058922. doi: 10.1136/bmjopen-2021-058922.ABSTRACTINTRODUCTION: Immune-inflammatory response plays a key role in the pathogenesis of atherosclerosis. IgG N-glycosylation is reported to be associated with the 10-year atherosclerotic cardiovascular disease risk score and subclinical atherosclerosis. However, the relationship of IgG glycosylation with actual clinical cardiovascular disease (CVD) events and plaque phenotypes has rarely been investigated. Therefore, this study aims to understand whether IgG glycosylation traits are correlated with actual clinical CVD events and plaque phenotypes.METH...
Source: Atherosclerosis - July 22, 2022 Category: Cardiology Authors: Cuihong Tian Gehendra Mahara Hongxia Zhang Xuerui Tan Source Type: research

Sex Differences in Intracranial Atherosclerotic Plaques Among Patients With Ischemic Stroke
CONCLUSION: For patients with ischemic stroke, the intracranial plaque burden in male patients was similar to that in female patients; however, the plaque characteristics in male patients are associated with higher risk, especially in culprit plaques.PMID:35845071 | PMC:PMC9280275 | DOI:10.3389/fcvm.2022.860675
Source: Atherosclerosis - July 18, 2022 Category: Cardiology Authors: Xuejiao Yan Min Tang Jie Gao Lihui Wang Ling Li Niane Ma Xiaorui Shi Xiaoyan Lei Xiaoling Zhang Source Type: research

The mechanism of action of the combination of Astragalus membranaceus and Ligusticum chuanxiong in the treatment of ischemic stroke based on network pharmacology and molecular docking
This study demonstrates that A&L can be used to treat IS by controlling the inflammatory response through multiple targets and multiple pathways, and provides a reference for subsequent trials.PMID:35839049 | DOI:10.1097/MD.0000000000029593
Source: Atherosclerosis - July 15, 2022 Category: Cardiology Authors: Tianyue Wang Xinyu Jiang Yanmin Ruan Lin Li Lisheng Chu Source Type: research

Association Between High-Sensitivity C-Reactive Protein and Prognosis in Different Periods After Ischemic Stroke or Transient Ischemic Attack
Conclusions Elevated levels of hsCRP measured in the first 72 hours after ischemic stroke or transient ischemic attack but not 72 hours to 8 days, were associated with an increased risk of 1-year stroke recurrence.PMID:35766270 | DOI:10.1161/JAHA.122.025464
Source: Atherosclerosis - June 29, 2022 Category: Cardiology Authors: Yu Wang Jiejie Li Yuesong Pan Mengxing Wang Xia Meng Yongjun Wang Source Type: research

Network pharmacological analysis of active components of Tongqiao Huoxue Decoction in the treatment of intracerebral hemorrhage
CONCLUSIONS: In summary, the results of this study suggest that the mechanism of action of TQHXD in the treatment of ICH involves multiple targets and signaling pathways related to its occurrence and development. This study not only provides a new theoretical basis for the treatment of ICH with traditional Chinese medicine, but also provides new ideas for the research and development of drugs for the treatment of ICH.PMID:35722393 | PMC:PMC9201131 | DOI:10.21037/atm-22-1403
Source: Atherosclerosis - June 20, 2022 Category: Cardiology Authors: Ji Wu Xue-Yu Li Jing Liang Jian Xie Cheng-Neng Deng Zhi-Jun Chen Chang-Sheng Lai Zhao-Jian Yang Source Type: research

Risk Factors of Ischemic Stroke in Young Adults: A Chinese Single-Center Study
CONCLUSIONS: The IPSS classification might be a potential tool to better identify the risk factors of ischemic stroke in young adults.PMID:35665043 | PMC:PMC9159801 | DOI:10.3389/fneur.2022.874770
Source: Atherosclerosis - June 6, 2022 Category: Cardiology Authors: Mingyu Tang Guangsong Han Ming Yao Bin Peng Yicheng Zhu Lixin Zhou Jun Ni Source Type: research

Glucose-6-phosphate Dehydrogenase Deficiency and Intracranial Atherosclerosis Stenosis in Stroke Patients
CONCLUSION: Stroke patients with G6PD deficiency have a higher prevalence and ICAS burden than those with normal G6PD, particularly those who are male, older, and hypertensive.PMID:35608963 | DOI:10.1111/ene.15418
Source: Atherosclerosis - May 24, 2022 Category: Cardiology Authors: Jianle Li Yicong Chen Zilin Ou Yusheng Zhang Zhijian Liang Weisheng Deng Hao Chen Weixian Huang Yingxin He Shihui Xing Jian Yu Jinsheng Zeng Source Type: research

The Beneficial Role of Nrf2 in the Endothelial Dysfunction of Atherosclerosis
This article examines the mechanisms and potential targets of Nrf2 affecting endothelial cell function to improve atherosclerosis and to provide ideas for the development of new CVD treatments.PMID:35600333 | PMC:PMC9119788 | DOI:10.1155/2022/4287711
Source: Cardiology Research and Practice - May 23, 2022 Category: Cardiology Authors: Zixia Huang Mingyue Wu Lijin Zeng Deming Wang Source Type: research