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Specialty: Neuroscience
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Total 250 results found since Jan 2013.
Unfavorable Outcome of Thrombolysis in Chinese Patients with Cardioembolic Stroke: a Prospective Cohort Study.
CONCLUSIONS: Patients with cardioembolic stroke had more SICH after thrombolysis, and worse clinical outcome at 3-month follow-up compared with those with LAA. This emphasizes the importance of preventing cardioembolism.
PMID: 26096605 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - June 20, 2015 Category: Neuroscience Authors: Wang XG, Zhang LQ, Liao XL, Pan YS, Shi YZ, Wang CJ, Wang YL, Liu LP, Zhao XQ, Wang YJ, Li D, Wang CX, Thrombolysis Implementation and Monitoring of acute ischemic Stroke in China (TIMS-China) Investigators Tags: CNS Neurosci Ther Source Type: research
Mediation effect of stroke recurrence in the association between post-stroke interleukin-6 and functional disability
CONCLUSIONS: Stroke recurrence mediates less than 20% of the association between IL-6 and functional outcome at 90 days among patients with acute ischemic stroke. In addition to typical secondary prevention strategies for preventing stroke recurrence, more attention should be paid to novel anti-inflammatory therapy to improve functional outcomes directly.PMID:37287421 | DOI:10.1111/cns.14289
Source: CNS Neuroscience and Therapeutics - June 8, 2023 Category: Neuroscience Authors: Hong-Qiu Gu Kai-Xuan Yang Jie-Jie Li Jin-Xi Lin Jing Jing Yun-Yun Xiong Xing-Quan Zhao Yi-Long Wang Li-Ping Liu Xia Meng Yong Jiang Hao Li Yong-Jun Wang Zi-Xiao Li Source Type: research
Elevated gamma-glutamyl transferase levels are associated with stroke recurrence after acute ischemic stroke or transient ischemic attack
CONCLUSION: This study demonstrated that elevated GGT levels were positively associated with an increased risk of stroke adverse outcomes, namely, recurrence, ischemic stroke, and combined vascular events.PMID:35789538 | DOI:10.1111/cns.13909
Source: CNS Neuroscience and Therapeutics - July 5, 2022 Category: Neuroscience Authors: Siqi Li Anxin Wang Xue Tian Yingting Zuo Xia Meng Yumei Zhang Source Type: research
Soluble lectin-like oxidized low-density Lipoproteinreceptor-1 and recurrent stroke: A nested case-control study
CONCLUSIONS: sLOX-1 was positively associated with the risk of recurrent stroke, which may be a candidate biomarker to improve risk stratification of recurrent stroke.PMID:35909324 | DOI:10.1111/cns.13932
Source: CNS Neuroscience and Therapeutics - August 1, 2022 Category: Neuroscience Authors: Anxin Wang Xue Tian Jie Xu Hao Li Qin Xu Pan Chen Xia Meng Yongjun Wang Source Type: research
HDAC9 Polymorphisms Predict Susceptibility, Severity, and Short-Term Outcome of Large Artery Atherosclerotic Stroke in Chinese Population
This study aimed to investigate whether these two polymorphisms were associated with susceptibility, severity, and short-term outcome of LAA stroke in a southern Chinese Han population. rs2074633 and rs28688791 were genotyped using SNPscan technology in 1011 LAA stroke patients and 1121 healthy controls. Stroke severity on admission and short-term outcome were, respectively, assessed by the National Institute of Health Stroke Scale (NIHSS) score on admission and modified Rankin Scale score at 3 months after stroke onset. rs2074633 (P = 0.039) and rs28688791 (P = 0.025) were associated with risk of LAA stroke. In ...
Source: Journal of Molecular Neuroscience - December 18, 2018 Category: Neuroscience Source Type: research
Two Novel SNPs in the PLCL2 Gene Associated with Large Artery Atherosclerotic Stroke Identified by Fine-Mapping
AbstractA genome-wide association study (GWAS) reported that the single nucleotide polymorphism (SNP) rs4618210 in thePLCL2 gene is related to myocardial infarction (MI) in the Japanese population, but no study has examined the correlation ofPLCL2 with ischemic stroke (IS). The present study was designed to investigate whether the genetic variation inPLCL2 is associated with large artery atherosclerotic (LAA) stroke in a Han Chinese population. Tagging SNPs (tSNPs) of thePLCL2 gene were determined by a fine-mapping strategy and were genotyped by improved multiplex ligation detection reaction (iMLDR) technology in 669 LAA s...
Source: Journal of Molecular Neuroscience - January 21, 2020 Category: Neuroscience Source Type: research
Association of serum uric acid to lymphocyte ratio, a novel inflammatory biomarker, with risk of stroke: A prospective cohort study
CONCLUSIONS: ULR was significantly associated with the risk of HS, but not with IS. Systolic blood pressure, diastolic blood pressure and estimated glomerular filtration rate were potential mediators for the association.PMID:36650955 | DOI:10.1111/cns.14094
Source: CNS Neuroscience and Therapeutics - January 18, 2023 Category: Neuroscience Authors: Xue Tian Penglian Wang Shuohua Chen Yijun Zhang Xiaoli Zhang Qin Xu Yanxia Luo Shouling Wu Anxin Wang Source Type: research
