Mediation effect of stroke recurrence in the association between post-stroke interleukin-6 and functional disability

CONCLUSIONS: Stroke recurrence mediates less than 20% of the association between IL-6 and functional outcome at 90 days among patients with acute ischemic stroke. In addition to typical secondary prevention strategies for preventing stroke recurrence, more attention should be paid to novel anti-inflammatory therapy to improve functional outcomes directly.PMID:37287421 | DOI:10.1111/cns.14289

Source: CNS Neuroscience and Therapeutics - June 8, 2023 Category: Neuroscience Authors: Hong-Qiu Gu Kai-Xuan Yang Jie-Jie Li Jin-Xi Lin Jing Jing Yun-Yun Xiong Xing-Quan Zhao Yi-Long Wang Li-Ping Liu Xia Meng Yong Jiang Hao Li Yong-Jun Wang Zi-Xiao Li Source Type: research