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Specialty: Cardiology
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Total 288 results found since Jan 2013.

Impact of previous percutaneous coronary interventions on the course and clinical outcomes of coronary artery bypass grafting.
CONCLUSIONS: "Stent-loaded" patients undergo more time-consuming CABG with a higher number of grafts. Furthermore, they have higher long-term mortality but similar graft patency and in-hospital mortality/morbidity. PMID: 29399760 [PubMed - indexed for MEDLINE]
Source: Kardiologia Polska - November 28, 2018 Category: Cardiology Authors: Bugajski P, Greberski K, Kuzemczak M, Kalawski R, Jarząbek R, Siminiak T Tags: Kardiol Pol Source Type: research

Antithrombotic Therapy for Atrial Fibrillation and Coronary Disease Demystified
Publication date: November 2018Source: Canadian Journal of Cardiology, Volume 34, Issue 11Author(s): Jason G. Andrade, Marc W. Deyell, Graham C. Wong, Laurent MacleAbstractAtrial fibrillation (AF) is a progressive chronic disease characterized by exacerbations and periods of remission. It is estimated that up to 20% to 30% of those with AF also have coronary artery disease (CAD), and 5% to 15% will require percutaneous coronary intervention (PCI). In patients with concomitant AF and CAD, management remains challenging and requires a careful and balanced assessment of the risk of bleeding against the anticipated impact on i...
Source: Canadian Journal of Cardiology - November 6, 2018 Category: Cardiology Source Type: research

The Guideline-Policy Gap in Direct-Acting Oral Anticoagulants Usage in Atrial Fibrillation: Evidence, Practice, and Public Policy Considerations
Publication date: November 2018Source: Canadian Journal of Cardiology, Volume 34, Issue 11Author(s): Douglas Wan, Jeff S. Healey, Chris S. SimpsonAbstractAtrial fibrillation has a high disease burden—both in prevalence and associated consequences. Despite anticoagulation being an effective treatment in atrial fibrillation, stroke prevention is slow to reflect evidence-based practice. Real-world data reveal a substantial portion of patients who would benefit from anticoagulation, yet do not receive it adequately or at all. A large part of this suboptimal treatment is due to the underutilization of direct oral anticoagulan...
Source: Canadian Journal of Cardiology - November 6, 2018 Category: Cardiology Source Type: research

Multiple Arterial Grafting Is Associated With Better Outcomes for Coronary Artery Bypass Grafting Patients.
CONCLUSIONS: CABG with 3 arterial grafts was not associated with increased in-hospital death nor with better clinical outcomes at 8-year follow-up, compared with CABG with 2 arterial grafts. MAG was associated with superior outcomes compared with SAG. PMID: 30474420 [PubMed - in process]
Source: Circulation - November 6, 2018 Category: Cardiology Authors: Rocha RV, Tam DY, Karkhanis R, Nedadur R, Fang J, Tu JV, Gaudino M, Royse A, Fremes SE Tags: Circulation Source Type: research

New Insights into the Use of Cardiac Magnetic Resonance Imaging to Guide Decision Making in Atrial Fibrillation Management
Publication date: Available online 12 July 2018Source: Canadian Journal of CardiologyAuthor(s): Tarek Zghaib, Saman NazarianAbstractRecent advances in cardiac magnetic resonance (CMR) imaging acquisition techniques have enabled the visualization of thin atrial myocardium with high temporal and spatial resolution and have the potential to shift atrial fibrillation (AF) management paradigms. Late gadolinium-enhancement (LGE)-CMR can noninvasively identify atrial arrhythmogenic scar substrates and has been shown to spatially correlate with low-voltage areas. Immediately after ablation, a combination of native T1-weighted, LGE...
Source: Canadian Journal of Cardiology - October 6, 2018 Category: Cardiology Source Type: research

XANTUS-EL: A real-world, prospective, observational study of patients treated with rivaroxaban for stroke prevention in atrial fibrillation in Eastern Europe, Middle East, Africa and Latin America
ConclusionsXANTUS-EL confirmed low stroke and major bleeding rates in patients with NVAF from EEMEA and Latin America. The population was younger but with more heart failure and hypertension than XANTUS; stroke/SE rate was similar but major bleeding lower.
Source: The Egyptian Heart Journal - October 5, 2018 Category: Cardiology Source Type: research

Patterns of incidence rates of cardiac complications in patients with congenital heart disease
ConclusionsCardiac complications are frequent in congenital heart disease. Apart from perioperative stroke and complete heart block, incidence rates are low in childhood but the incidence increases during adult life. These data underscore the need of life-long follow up and may help for better allocation of resources maintaining follow-up.
Source: Canadian Journal of Cardiology - October 4, 2018 Category: Cardiology Source Type: research

The multiple causes of stroke in atrial fibrillation: Thinking broadly
Publication date: Available online 30 August 2018Source: Canadian Journal of CardiologyAuthor(s): Atlantic D’Souza, Kenneth S. Butcher, Brian H. BuckAbstract:Atrial Fibrillation (AF) is numerically the most important risk factor for stroke. It is well established that patients with AF have a five-fold increased risk of stroke relative to those without, and that anticoagulation reduces the risk of stroke by approximately two-thirds. Definitively attributing the mechanism of an individual stroke to AF is much more problematic, however. In fact, there is no way to reliably establish the etiology of any ischemic infarction. ...
Source: Canadian Journal of Cardiology - August 31, 2018 Category: Cardiology Source Type: research

Early vs Late Surgery for Patients With Endocarditis and Neurological Injury: A Systematic Review and Meta-analysis
ConclusionsAvailable observational data support delaying surgery by 7-14 days if possible in IE complicated by ischemic stroke and> 21 days in hemorrhagic stroke to decrease perioperative mortality and neurological exacerbation rates. Randomized trials are needed for definitive guidance.RésuméIntroductionLe moment de l’intervention chirurgicale lors d’une endocardite infectieuse (EI) accompagnée d’événements neurologiques reste controversé. Les lignes directrices pertinentes de la Société reposent chacune sur un petit nombre d’études observationnelles. La présente méta-analyse a été conçue pour recher...
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research

Effects of Riociguat on Right Ventricular Remodelling in Chronic Thromboembolic Pulmonary Hypertension Patients: A Prospective Study
ConclusionsRiociguat treatment was associated with increased RV stroke volume index and trends for improvement in myocardial remodelling in patients with CTEPH. A larger clinical study is warranted to observe the therapeutic benefits of riociguat on RV remodelling.RésuméContexteLes effets du traitement par le riociguat sur le métabolisme, la perfusion et le débit du ventricule droit (VD) chez les patients atteints d’hypertension pulmonaire thromboembolique chronique (HPTC) sont inconnus. Dans la présente étude, nous analysons les changements aux ventriculaires droits associés au traitement par le riociguat.Méthod...
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research

Reply to Green et al.—Elevated Incidence of Atrial Fibrillation and Stroke in Patients With Atrial Flutter: A Population-Based Study
Publication date: September 2018Source: Canadian Journal of Cardiology, Volume 34, Issue 9Author(s): Lorne J. Gula, Damian P Redfearn, Krista B. Jenkyn, Britney Allen, Allan C. Skanes, Peter Leong-Sit, Salimah Z. Shariff
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research

The association of kidney function and albuminuria with the risk and outcomes of syncope: A population-based cohort study
ConclusionsA lower eGFR and higher ACR are associated with a higher risk of a hospital encounter for syncope, and of related complications among individuals of an advanced age.
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research

Antithrombotic Therapy for Atrial Fibrillation and Coronary Disease de-Mystified
Publication date: Available online 20 August 2018Source: Canadian Journal of CardiologyAuthor(s): Jason G. Andrade, Marc W. Deyell, Graham C. Wong, Laurent MacleABSTRACTAtrial fibrillation (AF) is a progressive chronic disease characterized by exacerbations and periods of remission. It is estimated that up to 20-30% of those with AF also have coronary artery disease (CAD), and 5-15% will require percutaneous coronary intervention (PCI). In patients with concomitant AF and CAD, management remains challenging and requires a careful and balanced assessment of the risk of bleeding against the anticipated impact on ischemic out...
Source: Canadian Journal of Cardiology - August 21, 2018 Category: Cardiology Source Type: research

The importance and future of population screening for atrial fibrillation
Publication date: Available online 17 August 2018Source: Canadian Journal of CardiologyAuthor(s): Seung Yong Shin, Gregory Y.H. LipAbstractAtrial fibrillation (AF) is a common and progressive heart rhythm disorder that causes structural, functional and electrical remodelling of the heart. Although we do not fully understand AF yet, this arrhythmia is one clinical feature of a syndrome that is represented by irregularly irregular atrial rhythm accompanied by progressive atrial structural and functional remodelling. Although ischemic stroke, most feared complication of AF, can be prevented by anticoagulation, asymptomatic or...
Source: Canadian Journal of Cardiology - August 18, 2018 Category: Cardiology Source Type: research

Determining the Optimal Systolic Blood Pressure for Hypertensive Patients: A Network Meta-analysis
ConclusionsSBP <130 mmHg is associated with a lower risk of stroke and major adverse cardiovascular events. Further lowering to <120 mmHg can be considered to reduce stroke risk if the therapy is tolerated. Long-term SBP should not exceed 150 mmHg because of increased risk of myocardial infarction and cardiac deaths.
Source: Canadian Journal of Cardiology - August 10, 2018 Category: Cardiology Source Type: research