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Exploring dimensions of quality-of-life in survivors of stroke with communication disabilities - a brief report
CONCLUSIONS: Survivors of stroke with communication disabilities are more negatively impacted across different dimensions of quality-of-life (as reported between 90 and 180 days post-stroke) compared to those without communication disabilities. This highlights the need for timely and on-going comprehensive multidisciplinary person-centered support.PMID:35786371 | DOI:10.1080/10749357.2022.2095087
Source: Topics in Stroke Rehabilitation - July 5, 2022 Category: Neurology Authors: T Thayabaranathan C Baker N E Andrew R Stolwyk A G Thrift H Carter K Moss J Kim S J Wallace E Brogan R Grimley N A Lannin M L Rose D A Cadilhac Source Type: research

Additional therapy promotes a continued pattern of improvement in upper-limb function and independence post-stroke
Stroke is considered a major worldwide health issue, and one of the leading causes of acquired disability in Australia, leading to lifelong impairment or death.1 Better recognition, management and medical treatment of acute stroke events have led to a reduction in both mortality2 and the severity of post-stroke impairments. The corollary of this sustained improvement in post-stroke outcomes is the growing number of survivors in the chronic phase living in the community and in need of ongoing rehabilitation, shifting our view towards stroke as a chronic disease rather than a single, neurological event.
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2023 Category: Neurology Authors: AG Thompson-Butel, SK Ashcroft, G Lin, T Trinh, PA McNulty Source Type: research

Exploring the Economic Benefits of Modafinil for Post-Stroke Fatigue in Australia: A Cost-Effectiveness Evaluation
Post-stroke fatigue remains a substantial ‘silent disability’, affecting up to three-quarters of stroke survivors,1,2 and rating among the worst symptoms experienced by nearly half of stroke survivors.3 On the spectrum of stroke complications, fatigue receives considerably less attention than more visible physical disabilities,4 despite fatigue adversely affecting clinical outcomes and quality of life, and being an independent predictor of institutionalisation, dependence in activities of daily living, poorer functional outcomes, and death.
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2020 Category: Neurology Authors: Beata Bajorek, Lan Gao, Tom Lillicrap, Andrew Bivard, Carlos Garcia-Esperon, Mark Parsons, Neil Spratt, Elizabeth Holliday, Chris Levi Source Type: research

Cost Burden and Cost-Effective Analysis of the Nationwide Implementation of the Quality in Acute Stroke Care Protocol in Australia
Stroke is the third global leading cause of death and disability.1,2 In Australia, stroke accounts for 3% of the total burden of disease and 5% of all deaths, with 36,700 incident strokes annually.3 Healthcare expenditure for stroke in Australia in 2017 was AUD 663 million.4
Source: Journal of Stroke and Cerebrovascular Diseases - June 19, 2021 Category: Neurology Authors: Clara Marquina, Zanfina Ademi, Ella Zomer, Richard Ofori-Asenso, Rhiannon Tate, Danny Liew Source Type: research

World-Wide Efficacy of Bone Marrow Derived Mesenchymal Stromal Cells in Preclinical Ischemic Stroke Models: Systematic Review and Meta-Analysis
Conclusions: Our results show worldwide efficacy of BM-MSCs in improving functional outcomes in pre-clinical animal models of stroke and support testing these cells in clinical trials in various ranges of time windows using different delivery routes. The continued growing number of publications showing functional benefit of BM-MSCs are now adding limited value to an oversaturated literature spanning 18 years. Researchers should focus on identifying definitive mechanisms on how BM-MSCs lead to benefit in stroke models. Introduction Ischemic stroke is the 5th leading cause of death and the leading cause of long term di...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Pre-hospital Triage of Acute Ischemic Stroke Patients —Importance of Considering More Than Two Transport Options
Conclusion: Pre-hospital triage algorithms for AIS patients that only take into account the nearest CSC and the nearest PSC as transport destinations may be unable to identify the optimal transport destination for a significant proportion of patients. Introduction Background International guidelines recommend early administration of intravenous thrombolysis for eligible patients with acute ischemic stroke (AIS); in addition, patients with proximal large vessel occlusion (LVO) should receive mechanical thrombectomy (MT) as quickly as possible (1). As the clinical benefit of both thrombolysis (2–4) and MT (5&#...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

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