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Reflection on Stroke Deaths and end ‐of‐life stroke care
ConclusionIn this cohort, palliative care referral and EOLCP were commenced in less than 50% of patients, highlighting significant variations in clinical care. These data support the need to promote awareness of ACP, particularly in patients with prior stroke or significant co‐morbidities. This may help reduce potentially futile invasive investigations and treatment.
Source: Internal Medicine Journal - September 11, 2017 Category: Internal Medicine Authors: Syed Zujajuddin Quadri, Thang Huynh, Cecilia Cappelen ‐Smith, Nirupama Wijesuriya, Abul Mamun, Roy Beran, Alan Mcdougall, Dennis Cordato Tags: Original Article Source Type: research

The effectiveness of home-based therapy on functional outcome, self-efficacy and anxiety among discharged stroke survivors
This study will provide the information on the effectiveness of HBT in comparison to UP among stroke population who are discharged from rehabilitation. Findings from the study will enable rehabilitation professionals to design effective discharge care plan for stroke survivors in combating functional decline when no longer receiving hospital-based therapy. Trial registration: Australian New Zealand Clinical Trials Registry, ACTRN12619001182189 (last updated 22/11/2019).
Source: Medicine - November 20, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research

Effectiveness of autogenic relaxation training in addition to usual physiotherapy on emotional state and functional independence of stroke survivors
Discussion: The expected main study outcome is an enhanced evidence-based physiotherapy program that may be used by physiotherapists in the rehabilitation of stroke patients with emotional disturbances. Trial registration: Australian New Zealand Clinical Trials Registry, ACTRN12619001664134 (last updated on 28/11/2019).
Source: Medicine - August 20, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research

Progression of diabetes, heart disease, and stroke multimorbidity in middle-aged women: A 20-year cohort study
ConclusionsStroke was associated with increased risk of progression to diabetes or heart disease. Social inequality, obesity, hypertension, physical inactivity, smoking, or having other chronic conditions were also significantly associated with increased odds of accumulating multimorbidity. Our findings highlight the importance of awareness of the role of diabetes, heart disease, and stroke multimorbidity among middle-aged women for clinicians and health-promotion agencies.
Source: PLoS Medicine - March 13, 2018 Category: Internal Medicine Authors: Xiaolin Xu Source Type: research

Generalization of the right acute stroke promotive strategies in reducing delays of intravenous thrombolysis for acute ischemic stroke: A meta-analysis
This study provided detailed information on the net and quantitative benefits of various programs for reducing time delays to facilitate the generalization of appropriate AIS management.
Source: Medicine - June 1, 2018 Category: Internal Medicine Tags: Research Article: Meta-Analysis of Observational Studies in Epidemiology Source Type: research

A Cohort Study of Anticholinergic Medication Burden and Incident Dementia and Stroke in Older Adults
ConclusionsHigh anticholinergic burden in initially healthy older people was associated with increased risk of incident dementia and ischemic stroke. A vascular effect may underlie this association. These findings highlight the importance of minimizing anticholinergic exposure in healthy older people.
Source: Journal of General Internal Medicine - March 22, 2021 Category: Internal Medicine Source Type: research

Epidemiology of atrial fibrillation
ConclusionsAlthough the prevalence of AF worldwide is increasing steadily, large variation can be seen between studies and countries. Further epidemiological studies should be undertaken globally, especially in Asian and African countries so that a better and more accurate picture of the incidence and prevalence of AF can be captured, to enable stroke prevention strategies to be appropriately implemented to prevent or reduce the risk of stroke, the most severe consequence of AF.
Source: International Journal of Clinical Practice - March 1, 2018 Category: Internal Medicine Authors: Hanis Zulkifly, Gregory Y. H. Lip, Deirdre A. Lane Tags: PERSPECTIVE Source Type: research

Associations of Serum Testosterone and Sex Hormone-Binding Globulin With Incident Cardiovascular Events in Middle-Aged to Older Men
CONCLUSION: Men with lower total testosterone concentrations were not at increased risk for MI, stroke, HF, or MACE. Calculated free testosterone may be associated with risk for MACE. Men with lower SHBG concentrations have higher risk for MI but lower risk for IS and HF, with causality to be determined.PRIMARY FUNDING SOURCE: Western Australian Health Translation Network, Medical Research Future Fund, and Lawley Pharmaceuticals.PMID:34958606 | DOI:10.7326/M21-0551
Source: Annals of Internal Medicine - December 27, 2021 Category: Internal Medicine Authors: Bu B Yeap Ross J Marriott Leen Antonio Suchitra Raj Girish Dwivedi Christopher M Reid Bradley D Anawalt Shalender Bhasin Adrian S Dobs David J Handelsman Graeme J Hankey Robin Haring Alvin M Matsumoto Paul E Norman Terence W O'Neill Claes Ohlsson Eric S O Source Type: research

External Validation of a Tool Predicting 7-Year Risk of Developing Cardiovascular Disease, Type 2 Diabetes or Chronic Kidney Disease
ConclusionsValidation of our previously developed tool showed robust discriminative performance across populations. Model recalibration is recommended to account for different disease rates. Our risk prediction tool can be useful in large-scale prevention programs for identifying those in need of further risk profiling because of their increased risk for chronic cardiometabolic diseases.
Source: Journal of General Internal Medicine - December 4, 2017 Category: Internal Medicine Source Type: research

Dedicated warfarin care programme results in superior warfarin control in Queensland, Australia
ConclusionAustralian warfarin control was good when managed by either GP or WCP, but WCP management increased TTR by 13%. Dedicated warfarin programmes can improve warfarin control and optimise therapy for patients.
Source: International Journal of Clinical Practice - January 9, 2018 Category: Internal Medicine Authors: Nijole Bernaitis, Tony Badrick, Shailendra Anoopkumar ‐Dukie Tags: ORIGINAL PAPER Source Type: research

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