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N-Acetylcysteine: A Review of Clinical Usefulness (an Old Drug with New Tricks)
CONCLUSION: The use of N-acetylcysteine should be considered in a number of conditions as our population ages and levels of glutathione drop. Supplementation may contribute to reducing morbidity and mortality in some chronic conditions as outlined in the article.PMID:34221501 | PMC:PMC8211525 | DOI:10.1155/2021/9949453
Source: Journal of Nutrition and Metabolism - July 5, 2021 Category: Nutrition Authors: Gerry K Schwalfenberg Source Type: research

Direct Oral Anticoagulants and Non-valvular Atrial Fibrillation: Compliance with Dose Level Guidelines in Patients Aged 80  Years and Over
ConclusionsAmong patients with non-valvular atrial fibrillation aged 80 years and over, about 40% of DOAC prescriptions feature inappropriate dose levels. It might be possible to reduce inappropriate dosing by raising awareness among hospital-based and private-practice prescribers, providing prescription support tools for DOACs, and performing medication reconciliations and reviews at hospital and in private practice.
Source: Drugs and Aging - September 6, 2021 Category: Geriatrics Source Type: research

Emergency Medical Service Workers Battle a Hurricane, and COVID-19, To Bring Health Care To New Orleans
As Hurricane Ida pounded the coast of New Orleans with downpours and 150-mile-per-hour winds on the afternoon of Aug. 29, New Orleans Emergency Medical Services had to reverse course after spending 18 months running around the city at full speed battling COVID-19: staying put. For 13 hours and 41 minutes, as the storm’s worst shook their community, the workers hunkered down at their base, keeping themselves safe to be ready to protect others from whatever came next. However, the deluge of 9-1-1 calls didn’t come to a halt as EMS waited out the storm. So, after EMS workers were given the go-ahead to rush back in...
Source: TIME: Health - September 7, 2021 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized climate change COVID-19 healthscienceclimate Source Type: news

Compound Developed at UArizona Health Sciences Provides Innovative Pain Relief
Digital media& downloads Compound Developed at UArizona Health Sciences Provides Innovative Pain Relief Researchers targeted a common sodium ion channel to reverse pain and saw positive results that could lead to a nonaddictive solution to treat pain. Today University of Arizona Health Sciencespain-relief-web.jpgHealthBIO5College of Medicine - TucsonExpertsResearch Media contact(s)Stacy Pigott University of Arizona Health Sciencesspigott@arizona.edu520-539-4152Researchers at the  University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that...
Source: The University of Arizona: Health - November 15, 2021 Category: Universities & Medical Training Authors: mittank Source Type: research

COVID-19, Overdoses Made 2021 The Deadliest Year in U.S. History
2021 was the deadliest year in U.S. history, and new data and research are offering more insights into how it got that bad. The main reason for the increase in deaths? COVID-19, said Robert Anderson, who oversees the Centers for Disease Control and Prevention’s work on death statistics. The agency this month quietly updated its provisional death tally. It showed there were 3.465 million deaths last year, or about 80,000 more than 2020’s record-setting total. Early last year, some experts were optimistic that 2021 would not be as bad as the first year of the pandemic — partly because effective COVID-19 vac...
Source: TIME: Health - April 12, 2022 Category: Consumer Health News Authors: MIKE STOBBE / AP Tags: Uncategorized COVID-19 healthscienceclimate wire Source Type: news

Appropriateness of Non-vitamin K Antagonist Oral Anticoagulants Dosing According to Different Prescription Guides Used in Belgian Ambulatory Care
ConclusionsInappropriate NOAC dosing is present in almost twenty percent of AF patients according to the SmPC and requires further education of health care professionals and frequent reassessment of NOAC dosing. However, a significant lower prevalence of underdosing was present when judged by the 2018 EHRA criteria, likely reflecting decision making in complex AF patients. Perceived frailty, weight, renal function and type of NOAC are the main determinants of deviated dosing.
Source: Clinical Drug Investigation - August 20, 2022 Category: Drugs & Pharmacology Source Type: research

Prevalence and risk of inappropriate dosing of direct oral anticoagulants in two Swiss atrial fibrillation registries
CONCLUSION: Inappropriate DOAC-dosing was more prevalent in multimorbid patients, but did not correlate with higher risks of adverse events after adjusting for confounders. DOAC prescription should follow label.PMID:36182083 | DOI:10.1016/j.vph.2022.107120
Source: Vascular Pharmacology - October 1, 2022 Category: Drugs & Pharmacology Authors: Giulia Montrasio Martin F Reiner Andrea Wiencierz Stefanie Aeschbacher Christine Baumgartner Nicolas Rodondi Michael K ühne Giorgio Moschovitis Helga Preiss Michael Coslovsky Maria L De Perna Leo H Bonati David Conen Stefan Osswald Juerg H Beer Pascal Ko Source Type: research

Unlucky numbers: Fighting murder convictions that rest on shoddy stats
LEIDEN, THE NETHERLANDS— When a Dutch nurse named Lucia de Berk stood trial for serial murder in 2003, statistician Richard Gill was aware of the case. But he saw no reason to stick his nose into it. De Berk was a pediatric nurse at Juliana Children’s Hospital in The Hague. In 2001, after a baby died while she was on duty, a colleague told superiors that De Berk had been present at a suspiciously high number of deaths and resuscitations. Hospital staff immediately informed the police. When investigators reexamined records from De Berk’s shifts, they found 10 suspicious incidents. Three other hospitals where D...
Source: Science of Aging Knowledge Environment - January 19, 2023 Category: Geriatrics Source Type: research

Demi Lovato Unleashes ‘Scream VI’ Cut ‘Still Alive’: Stream It Now
After cutting seven studio albums, changing style and music direction in the fickle pop world, and surviving a near fatal overdose, yes, Demi Lovato is still alive. At the stroke of midnight, the U.S. artist dropped “Still Alive,” her contribution to the Scream VI soundtrack. It’s the first taste…#demilovato #stillalive #lovato #holyfvck #yungblud #topalternativealbums #mikeshinoda #ghostface #jensennoen
Source: Reuters: Health - March 3, 2023 Category: Consumer Health News Source Type: news