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Condition: Ventricular Arrhythmia
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Total 76 results found since Jan 2013.
Janssen Demonstrates Commitment to Advancing Science and Innovation in the Treatment of Solid Tumors at ESMO Annual Congress
September 8, 2021 (RARITAN, N.J.) – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than ten data presentations from its lung cancer, bladder cancer and prostate cancer portfolio and pipeline will be featured during the European Society for Medical Oncology (ESMO) Annual Congress 2021 virtual meeting, September 16–21. Further details about these data and the science Janssen is advancing will be made available throughout ESMO via the Janssen Oncology Virtual Newsroom.“With a diverse oncology portfolio and pipeline spanning bladder cancer, lung cancer and prostate cancer, Janssen...
Source: Johnson and Johnson - September 8, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
Neuronal and cardiac toxicity of pharmacological compounds identified through transcriptomic analysis of human pluripotent stem cell-derived embryoid bodies
In this study, we used human induced pluripotent stem cell (hiPSC)-derived embryoid bodies (EB) as an in vitro model to investigate the embryotoxic effects of a carefully selected set of pharmacological compounds. Morphology, viability, and differentiation potential were investigated after exposing EBs to folic acid, all-trans-retinoic acid, dexamethasone, and valproic acid for 15 days. The results showed that the compounds differentially repressed cell growth, compromised morphology, and triggered apoptosis in the EBs. Further, transcriptomics was employed to compare subtle temporal changes between treated and untreated c...
Source: Toxicology and Applied Pharmacology - November 7, 2021 Category: Toxicology Authors: Vijay Bhaskar Reddy Konala Swapna Nandakumar Harshini Surendran Savita Datar Ramesh Bhonde Rajarshi Pal Source Type: research
Heart transplantation strategies in arrhythmogenic right ventricular cardiomyopathy: a tertiary ARVC centre experience
ConclusionsHeart transplantation is a curative treatment for ARVC, but due to frequent ventricular arrhythmias and RV predominant pathology, patients require unique considerations in regard to timing of evaluation, haemodynamic support options, and wait listing qualification.
Source: ESC Heart Failure - December 25, 2021 Category: Cardiology Authors: Paul J. Scheel,
Katherine Giuliano,
Crystal Tichnell,
Cynthia James,
Brittney Murray,
Harikrishna Tandri,
Debra Carter,
Tracey Fehr,
Priya Umapathi,
Joban Vaishnav,
Sabra C. Lewsey,
Steven Hsu,
Hugh Calkins,
Kavita Sharma,
Chun Woo Choi,
Ni Tags: Original Article Source Type: research
In-hospital adverse events in low-risk patients with acute myocardial infarction - Potential implications for earlier discharge
CONCLUSION: In patients with acute MI with low GRACE and/or CADILLAC risk scores who were free from acute events within 3 days, early discharge after primary percutaneous coronary intervention may be feasible and safe.PMID:35078684 | DOI:10.1016/j.jjcc.2022.01.003
Source: Journal of Cardiology - January 26, 2022 Category: Cardiology Authors: Takanori Sato Yuichi Saito Tadahiro Matsumoto Daichi Yamashita Kan Saito Shinichi Wakabayashi Hideki Kitahara Koichi Sano Yoshio Kobayashi Source Type: research
GSE195617 Neuronal and cardiac toxicity of pharmacological compounds identified through transcriptomic analysis of human pluripotent stem cell-derived embryoid bodies
In this study, we used human induced pluripotent stem cell (hiPSC)-derived embryoid bodies (EB) as an in vitro model to investigate the embryotoxic effects of a carefully selected set of pharmacological compounds. Morphology, viability, and differentiation potential were investigated after exposing EBs to folic acid, all-trans-retinoic acid, dexamethasone, and valproic acid for 15 days. The results showed that the compounds differentially repressed cell growth, compromised morphology, and triggered apoptosis in the EBs. Further, transcriptomics was employed to compare subtle temporal changes between treated and untreated c...
Source: GEO: Gene Expression Omnibus - January 31, 2022 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Clinical Characteristics of Patients with Arrhythmias of the Idiopathic Outflow Tract Ventricular: Age, Gender, Comorbidities, Laboratory Test Results, and Echocardiographic Parameters
CONCLUSIONS: The outflow tract served as the major original site of IVAs, and significant differences existed between participants in the LVOT and RVOT groups in age; gender; comorbidities; results of laboratory examinations, including red-blood-cell counts, hemoglobin, creatinine, and GGT; and echocardiographic parameters, including LVEF%, LAD, LVEDD, IVS, and LVPWT.PMID:35687704
Source: Alternative Therapies in Health and Medicine - June 10, 2022 Category: Complementary Medicine Authors: Lei Zhao Ruibin Li Jidong Zhang Ruiqin Xie Jingchao Lu Jinming Liu Chenglong Miao Suyun Liu Wei Cui Source Type: research
