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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Atrial Fibrillation

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Total 320 results found since Jan 2013.

Impaired Renal Function in Stroke Patients with Atrial Fibrillation
In this study, we analyzed frequency and predictors for impaired renal function and its impact on functional outcome in stroke patients with underlying AF.Methods: We analyzed 272 patients with acute ischemic stroke and AF of our prospective, observational stroke database. Estimated glomerular filtration rate (eGFR) was calculated on admission and during hospitalization from the equation of the Modification Diet for Renal Disease. Outcome measures included mortality and functional outcome at 90 days, assessed as modified Rankin Scale (mRS) score.Results: On admission, impaired renal function was found in 41.5% (n = 113)...
Source: Journal of Stroke and Cerebrovascular Diseases - November 25, 2013 Category: Neurology Authors: Eva-Maria Sauer, Roland Sauer, Bernd Kallmünzer, Christian Blinzler, Lorenz Breuer, Hagen B. Huttner, Stefan Schwab, Martin Köhrmann Tags: Original Articles Source Type: research

Atrial Fibrillation and Paroxysmal Atrial Fibrillation Detection in Patients with Acute Ischemic Stroke
Conclusions: AF/PAF was one of the common causes of ischemic stroke in Thai patients. Most PAF was detected by continuous ECG monitoring. Snapshot 12-lead ECG and continuous ECG monitoring should be recommended in all patients with acute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - November 4, 2013 Category: Neurology Authors: Panee Sutamnartpong, Pornpatr A. Dharmasaroja, Disya Ratanakorn, IngOrn Arunakul Tags: Original Articles Source Type: research

Net Clinical Benefit of Rivaroxaban versus Warfarin in Japanese Patients with Nonvalvular Atrial Fibrillation: A Subgroup Analysis of J-ROCKET AF
Conclusion: Analysis of the NCB supports that rivaroxaban therapy provides clinical benefit for Japanese patients with AF.
Source: Journal of Stroke and Cerebrovascular Diseases - November 4, 2013 Category: Neurology Authors: Shinichiro Uchiyama, Masatsugu Hori, Masayasu Matsumoto, Norio Tanahashi, Shin-ichi Momomura, Shinya Goto, Tohru Izumi, Yukihiro Koretsune, Mariko Kajikawa, Masaharu Kato, Hitoshi Ueda, Kazuma Iekushi, Satoshi Yamanaka, Masahiro Tajiri, J-ROCKET AF Study Tags: Original Articles Source Type: research

Metformin-inclusive Therapy Reduces the Risk of Stroke in Patients with Diabetes: A 4-Year Follow-up Study
Metformin is a kind of oral hypoglycemic agents commonly prescribed to patients with diabetes mellitus. Although past studies had proven its protective effect on cardiovascular risk and related mortality, the evidence of metformin on stroke prevention was still insufficient and conflicting. Our study randomly selected 14,856 patients with diabetes from the database provided by the Taiwan National Health Research Institute, and 2 cohorts were formulated according to whether metformin was in the prescription record. All cases were followed up for 4 years to track their stroke incidence. As a result, 701 (17.5%) of 3999 diabe...
Source: Journal of Stroke and Cerebrovascular Diseases - October 11, 2013 Category: Neurology Authors: Yuan-Yang Cheng, Hsin-Bang Leu, Tzeng-Ji Chen, Chen-Ling Chen, Chia-Hua Kuo, Shin-Da Lee, Chung-Lan Kao Tags: Original Articles Source Type: research

Internal Cerebral Vein Asymmetry on Follow-up Brain Computed Tomography after Intravenous Thrombolysis in Acute Anterior Circulation Ischemic Stroke Is Associated with Poor Outcome
Background: Identifying early predictors of functional outcome after acute ischemic stroke (AIS) is important for planning rehabilitation strategies. Internal cerebral veins (ICV) drain deep parts of brain, run parallel to each other, and consistently seen on computed tomography angiography (CTA). Even minor asymmetry in their filling can be identified. We hypothesized that venous drainage would be impaired in patients with acute occlusion of internal carotid artery or middle cerebral artery. Because systemic thrombolysis can alter the vascular findings, we evaluated the relationship between ICV asymmetry on follow-up CTA ...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Vijay K. Sharma, Leonard L.L. Yeo, Hock L. Teoh, Liang Shen, Bernard P.L. Chan, Raymond C. Seet, Aftab Ahmad, Vincent F. Chong, Prakash R. Paliwal Tags: Original Articles Source Type: research

Incidence and Cost of Stroke and Hemorrhage in Patients Diagnosed with Atrial Fibrillation in France
Conclusions: The incidence and cost of hospitalization for hemorrhage should be considered in the global burden of AF. These data should be useful for pharmacoeconomic evaluation of new oral anticoagulant medications. Such real-world studies may be relevant for monitoring mid- to long-term morbidity and mortality in the AF population.
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: François-Emery Cotté, Gwendoline Chaize, Isabelle Kachaner, Anne-Françoise Gaudin, Alexandre Vainchtock, Isabelle Durand-Zaleski Tags: Original Articles Source Type: research

Discrimination of Acute Ischemic Stroke from Nonischemic Vertigo in Patients Presenting with Only Imbalance
We examined 332 consecutive patients with an acute feeling of imbalance who showed no neurologic findings or responsible lesions on CT scan at the hyperacute phase. We examined their clinical backgrounds, physical findings, and laboratory examinations, with ischemic stroke diagnosed by later CT and/or magnetic resonance imaging (MRI). We identified 41 (12.3%) ischemic stroke patients. Atrial fibrillation (odds ratio 4.1; 95% confidence interval 1.4-11.5), white blood cell count (103/μL, 1.4; 1.2-1.6), head and/or neck pain (4.6; 2.1-10.3), first attack of imbalance feeling (3.3; 1.1-12.2), and dizziness (3.7; 1.7-8.3) wer...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Shoji Honda, Yuichiro Inatomi, Toshiro Yonehara, Yoichiro Hashimoto, Teruyuki Hirano, Yukio Ando, Makoto Uchino Tags: Original Articles Source Type: research

Brain Natriuretic Peptide in Acute Ischemic Stroke
Elevated serum brain natriuretic peptide (BNP) levels are associated with cardioembolic stroke mainly because of atrial fibrillation (AF). However, the mechanisms of increased serum BNP levels are hitherto unclear. We aimed to identify the factors associated with increased BNP levels in patients with acute ischemic stroke. We measured serum BNP levels in consecutive patients aged 18 years or older. Stroke subtypes were classified using the Trial of ORG 10172 in Acute Stroke Treatment criteria. Categorical variables included age, sex, smoking status, alcohol consumption status, hypertension, diabetes mellitus, dyslipidemia...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Kenji Maruyama, Tsuyoshi Shiga, Mutsumi Iijima, Saori Moriya, Satoko Mizuno, Sono Toi, Kotaro Arai, Kyomi Ashihara, Kayoko Abe, Shinichiro Uchiyama Tags: Original Articles Source Type: research

Factors Associated with Proximal Carotid Axis Occlusion in Patients with Acute Stroke and Atrial Fibrillation
Conclusions: Female sex, advanced age, history of systemic embolism, and higher BNP level were independently associated with more proximal carotid axis occlusion. Patients with AF having these factors may be prone to have relatively large thrombi in the heart.
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2013 Category: Neurology Authors: Yuki Sakamoto, Shoichiro Sato, Yuka Kuronuma, Kazuyuki Nagatsuka, Kazuo Minematsu, Kazunori Toyoda Tags: Original Articles Source Type: research

Vitamin K Antagonist–associated Intracerebral Hemorrhage: Lessons from a Devastating Disease in the Dawn of the New Oral Anticoagulants
Conclusions: VKA-associated ICH presents in a particularly vulnerable population and has a poor prognosis that may be reliably predicted by several clinicoradiologic features.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Marta Suárez-Pinilla, Ángeles Fernández-Rodríguez, Lorena Benavente-Fernández, Sergio Calleja-Puerta Tags: Original Articles Source Type: research

Rivaroxaban versus Warfarin in Japanese Patients with Nonvalvular Atrial Fibrillation in Relation to the CHADS2 Score: A Subgroup Analysis of the J-ROCKET AF Trial
Conclusion: This subanalysis indicated that the safety and efficacy of rivaroxaban compared with warfarin were similar, regardless of CHADS2 score.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Masatsugu Hori, Masayasu Matsumoto, Norio Tanahashi, Shin-ichi Momomura, Shinichiro Uchiyama, Shinya Goto, Tohru Izumi, Yukihiro Koretsune, Mariko Kajikawa, Masaharu Kato, Hitoshi Ueda, Kazuma Iekushi, Satoshi Yamanaka, Masahiro Tajiri, J-ROCKET AF Study Tags: Original Articles Source Type: research

Response to the Letter by Fustinoni et al
We thank Dr Pant et al for their interest on our study, which identified a seasonal variation and a nonhomogeneous distribution of atrial fibrillation across air temperatures, with peaks in cold seasons and low temperatures in a cohort of acute ischemic stroke patients. The evidence of a seasonal variation in atrial fibrillation–related hospitalizations showed by Deshmukh et al in their interesting study contributes to reinforcing the hypothesis of higher frequencies of atrial fibrillation in colder seasons. Similarly, a seasonal variation has been demonstrated for stroke incidence and mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - August 1, 2013 Category: Neurology Authors: Osvaldo Fustinoni, Gustavo Saposnik, Luciano A. Sposato Tags: Letters to the Editor Source Type: research

Higher Frequency of Atrial Fibrillation Linked to Colder Seasons and Air Temperature on the Day of Ischemic Stroke Onset
We read with great interest the article published by Fustinoni et al entitled “Higher frequency of atrial fibrillation linked to colder seasons and air temperature on the day of ischemic stroke onset” in the Journal of Stroke and Cardiovascular Diseases. We have recently analyzed Nationwide Inpatient Sample, a nationally representative survey of hospitalizations in the United States and found that there is a substantial increase in atrial fibrillation (AF)–related hospitalization in colder months and decreased hospitalization in warmer months. Such findings have been replicated from other nations as well. Environme...
Source: Journal of Stroke and Cerebrovascular Diseases - July 19, 2013 Category: Neurology Authors: Sadip Pant, Apurva O. Badheka, Abhishek Deshmukh Tags: Letters to the Editor Source Type: research

Atrial Fibrillation Detected after Acute Ischemic Stroke: Evidence Supporting the Neurogenic Hypothesis
Background: It is unknown whether atrial fibrillation (AF) detected after acute ischemic stroke is caused by neurogenic or cardiogenic mechanisms. Based on the potential damage to the autonomic nervous system, neurogenic mechanisms could be implicated in the pathophysiology of newly diagnosed AF. To test this hypothesis, we developed a mechanistic approach by comparing a prespecified set of indicators in acute ischemic stroke patients with newly diagnosed AF, known AF, and sinus rhythm.Methods: We prospectively assessed every acute ischemic stroke patient undergoing continuous electrocardiographic monitoring from 2008 thro...
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2013 Category: Neurology Authors: María E. González Toledo, Francisco R. Klein, Patricia M. Riccio, Fátima Pagani Cassará, Francisco Muñoz Giacomelli, Juan M. Racosta, Eleanor S. Roberts, Luciano A. Sposato Tags: Original Articles Source Type: research

Indecision in the Clinical Practice of Anticoagulation for Brief Atrial Arrhythmias after Cryptogenic Stroke
Conclusion: Our study demonstrates the differences in anticoagulant prescribing practices between neurologists and cardiologists and the inherent indecision these findings have produced. Further study is needed to better define the risks and benefits associated with anticoagulation of brief episodes of atrial arrhythmias lasting less than 30 seconds in patients with cryptogenic stroke or TIA.
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2013 Category: Neurology Authors: Muhib Khan, Daniel J. Miller, Lonni R. Schultz Tags: Original Articles Source Type: research