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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Atrial Fibrillation
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Total 320 results found since Jan 2013.
Design and Rationale of the RELAXED (Recurrent Embolism Lessened by rivaroxaban, an Anti-Xa agent, of Early Dosing for acute ischemic stroke and transient ischemic attack with atrial fibrillation) Study
In the acute phase of cardioembolic stroke in patients with nonvalvular atrial fibrillation (NVAF), the recurrence rate is high. Nonvitamin K antagonist oral anticoagulants may be appropriate for prevention of early recurrence because they have a much lower risk of hemorrhagic stroke than warfarin.
Source: Journal of Stroke and Cerebrovascular Diseases - March 14, 2016 Category: Neurology Authors: Masahiro Yasaka, Kazuo Minematsu, Kazunori Toyoda, Hiroshi Yamagami, Shinichi Yoshimura, Takehiko Nagao, Etsuro Mori, Teruyuki Hirano, Toshimitsu Hamasaki, Takenori Yamaguchi Source Type: research
Dabigatran Plasma Levels in Acute Cerebrovascular Events
Oral anticoagulation with dabigatran was shown to be effective for stroke prevention in patients with nonvalvular atrial fibrillation without the need for laboratory monitoring. However, a recent publication based on data of the Randomized Evaluation of Long-Term Anticoagulation Therapy study reported that ischemic stroke and bleeding outcomes are correlated with dabigatran plasma concentration (DPC). DPC was determined at a prespecified time point and correlated with cardiovascular events at any time during follow-up.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2016 Category: Neurology Authors: Bastian Volbers, Martin Köhrmann, Bernd Kallmünzer, Natalia Kurka, Lorenz Breuer, Jürgen Ringwald, Stefan Schwab Source Type: research
Predicting the Outcomes of Acute Ischemic Stroke with Rheumatic Heart Disease: The Values of CHADS2, CHA2DS2–VASc, and HAS-BLED Scores
The CHADS2 and CHA2DS2–VASc score were used to evaluate the atrial fibrillation-related risk of stroke, and HAS-BLED score was used to estimate the oral anticoagulation-bleeding risk. We investigated the relationships between these 3 scores and the outcomes of acute ischemic stroke (AIS) patients with rheumatic heart disease (RHD) at 3 months after stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 8, 2016 Category: Neurology Authors: Junfeng Liu, Deren Wang, Ge Tan, Ruozhen Yuan, Mangmang Xu, Yao Xiong, Ming Liu Source Type: research
Secondary Prevention of Stroke with Warfarin in Patients with Nonvalvular Atrial Fibrillation: Subanalysis of the J-RHYTHM Registry
Prior ischemic stroke or transient ischemic attack (TIA) is a high risk for thromboembolism in patients with nonvalvular atrial fibrillation (NVAF). To clarify rates of thromboembolic and hemorrhagic events, and target intensities of warfarin for secondary prevention, a subanalysis was performed using data from the J-RHYTHM Registry.
Source: Journal of Stroke and Cerebrovascular Diseases - December 22, 2015 Category: Neurology Authors: Eitaro Kodani, Hirotsugu Atarashi, Hiroshi Inoue, Ken Okumura, Takeshi Yamashita, Hideki Origasa, J-RHYTHM Registry Investigators Source Type: research
Predicting Paroxysmal Atrial Fibrillation in Cerebrovascular Ischemia Using Tissue Doppler Imaging and Speckle Tracking Echocardiography
Often the underlying cause of cerebral ischemia (CI) cannot be found during a routine diagnostic investigation, but paroxysmal atrial fibrillation (PAF) could be the culprit.
Source: Journal of Stroke and Cerebrovascular Diseases - November 2, 2015 Category: Neurology Authors: Flemming Javier Olsen, Peter Godsk Jørgensen, Rasmus Møgelvang, Jan Skov Jensen, Thomas Fritz-Hansen, Jan Bech, Tor Biering-Sørensen Source Type: research
Gender Differences in Fibrin Polymerization and Lysability of Fibrin in Patients with Atrial Fibrillation
Atrial fibrillation (AF) is the most common cardiac arrhythmia for both men and women. The embolic cardiovascular events represent serious complications of AF, and apparently women are affected more seriously than men. Little is known about prothrombotic factors and possible gender differences. The present study aimed to characterize fibrin polymerization, fibrinolysis, and fibrin fiber properties in men and in women with AF.
Source: Journal of Stroke and Cerebrovascular Diseases - October 28, 2015 Category: Neurology Authors: Jørgen Gram, Jane Skov, Else Marie Bladbjerg, Johannes Sidelmann, Jørgen Jespersen Source Type: research
Net Clinical Benefits of Guidelines and Decision Tool Recommendations for Oral Anticoagulant Use among Patients with Atrial Fibrillation
The 2012 American College of Chest Physicians' Evidence-Based Clinical Practice (CHEST), the 2012 European Society of Cardiology, and the 2014 American Heart Association guidelines and published decision tools by LaHaye and Casciano offer oral anticoagulant (OAC) recommendations for patients with atrial fibrillation (AF). The aim of our study was to compare the net clinical benefit (NCB) of OAC prescribing that was concordant with these decision aids.
Source: Journal of Stroke and Cerebrovascular Diseases - October 15, 2015 Category: Neurology Authors: Anand R. Shewale, Jill T. Johnson, Chenghui Li, David Nelsen, Bradley C. Martin Source Type: research
Atrial Cardiopathy and Cryptogenic Stroke: A Cross-sectional Pilot Study
There is increasing evidence that left atrial dysfunction or cardiopathy is associated with ischemic stroke risk independently of atrial fibrillation. We aimed to determine the prevalence of atrial cardiopathy biomarkers in patients with cryptogenic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2015 Category: Neurology Authors: Shadi Yaghi, Amelia K. Boehme, Rebecca Hazan, Eldad A. Hod, Alberto Canaan, Howard F. Andrews, Hooman Kamel, Randolph S. Marshall, Mitchell S.V. Elkind Source Type: research
What Do Anticoagulants Say about Microemboli?
In this study, we evaluated the microembolic signals (MES) frequency with transcranial Doppler ultrasound (TCD) in patients with atrial fibrillation (AF) under anticoagulant therapy, and we compared the treatment groups.
Source: Journal of Stroke and Cerebrovascular Diseases - September 14, 2015 Category: Neurology Authors: Serkan Demir, Mehmet F. Ozdag, Mustafa T. Kendirli, Rifat E. Togrol Source Type: research
Stroke Risk Perception in Atrial Fibrillation Patients is not Associated with Clinical Stroke Risk
Clinical risk stratification models, such as the CHA2DS2-VASc, are used to assess stroke risk in atrial fibrillation (AF) patients. No study has yet investigated whether and to which extent these patients have a realistic perception of their personal stroke risk. The purpose of this study was to investigate and describe the association between AF patients' stroke risk perception and clinical stroke risk.
Source: Journal of Stroke and Cerebrovascular Diseases - September 11, 2015 Category: Neurology Authors: Anders Fournaise, Jane Skov, Else-Marie Bladbjerg, Anja Leppin Source Type: research
Impact of Sex Difference on Severity and Functional Outcome in Patients with Cardioembolic Stroke
Female sex is a risk factor for thromboembolic events in Caucasian, but not in Japanese, patients with nonvalvular atrial fibrillation. However, it remains unclear whether the female sex is also a risk factor for severe stroke and unfavorable functional outcome in patients with cardioembolic (CE) stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - September 2, 2015 Category: Neurology Authors: Hirofumi Tomita, Joji Hagii, Norifumi Metoki, Shin Saito, Hiroshi Shiroto, Hiroyasu Hitomi, Takaatsu Kamada, Satoshi Seino, Koki Takahashi, Yoshiko Baba, Satoko Sasaki, Takamitsu Uchizawa, Manabu Iwata, Shigeo Matsumoto, Yoshihiro Shoji, Tomohiro Tanno, T Source Type: research
Efficacy and Safety of Edoxaban in Nonvalvular Atrial Fibrillation: A Meta-analysis of Randomized Controlled Trials
This study compared the efficacy and safety of edoxaban and warfarin in nonvalvular atrial fibrillation, and the effects of different edoxaban dosages. Methods: A systematic search for randomized controlled trials comparing edoxaban with warfarin in nonvalvular atrial fibrillation was conducted using PubMed, EMBASE, and the Cochrane Library databases.
Source: Journal of Stroke and Cerebrovascular Diseases - August 28, 2015 Category: Neurology Authors: Junyu Chen, Xiaodong Zhuang, Ming Long, Chen Su, Lichun Wang Source Type: research
Left Atrial Volume Index Predicts Recurrence of Stroke in Patients with Nonsustained Atrial Tachycardia
Nonsustained atrial tachycardia (NSAT) is known to appear more frequently in patients with paroxysmal atrial fibrillation (AF). Enlarged left atrium (LA) is considered to be an independent risk factor for newly diagnosed AF.
Source: Journal of Stroke and Cerebrovascular Diseases - August 10, 2015 Category: Neurology Authors: Hyemoon Chung, Boyoung Joung, Kyung-Yul Lee, Jae-Sun Uhm, Hui-Nam Pak, Moon-Hyoung Lee, Jong-Youn Kim Source Type: research
HRS/NSA 2014 Survey of Atrial Fibrillation and Stroke: Gaps in Knowledge and Perspective, Opportunities for Improvement
The prevalence of atrial fibrillation (AF) is substantial and increasing. Stroke is common in AF and can have devastating consequences. Oral anticoagulants are effective in reducing stroke risk, but are underutilized.
Source: Journal of Stroke and Cerebrovascular Diseases - August 1, 2015 Category: Neurology Authors: David S. Frankel, Sarah E. Parker, Lynda E. Rosenfeld, Philip B. Gorelick Tags: Review Article Source Type: research
International Normalized Ratio Variability: A Measure of Anticoagulation Quality or a Powerful Mortality Predictor
As atrial fibrillation (AF) carries twice the mortality hazard when compared with a similar population without diagnosed AF, the importance of risk stratifying is obvious. Several variables are related to outcome: age, comorbidities, and use of several medications, particularly oral anticoagulants. The CHA2DS2VASc score is an extremely useful tool to predict thromboembolic events and also mortality. The international normalized ratio (INR) variability is a treatment efficacy variable also associated with morbidity in patients receiving warfarin.
Source: Journal of Stroke and Cerebrovascular Diseases - July 29, 2015 Category: Neurology Authors: Gabriel Vanerio Source Type: research
