• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Effectiveness and safety of oral anticoagulants for non-valvular atrial fibrillation: a population-based cohort study in primary healthcare in Catalonia
Conclusion: Being men, a previous event and DOAC-switch posed a higher risk for all study outcomes. direct oral anticoagulants had a protective effect against cerebral bleeding in comparison to vitamin K antagonists. Adherence to direct oral anticoagulants resulted in lower risk of stroke and cerebral bleeding. We found no differences in the risk of stroke and gastrointestinal bleeding when we compared direct oral anticoagulants vs. vitamin K antagonists.
Source: Frontiers in Pharmacology - September 15, 2023 Category: Drugs & Pharmacology Source Type: research

Association of oral bisphosphonates with cardioembolic ischemic stroke: a nested case-control study
Conclusion: The use of oral bisphosphonates increases specifically the odds of cardioembolic IS, in a duration-dependent manner, while leaves materially unaffected the odds of non-cardioembolic IS.
Source: Frontiers in Pharmacology - May 26, 2023 Category: Drugs & Pharmacology Source Type: research

Sex and gender differences in the use of oral anticoagulants for non-valvular atrial fibrillation: A population-based cohort study in primary health care in catalonia
Conclusion: We described the dose adequacy of patients receiving DOAC, finding a high frequency of underdosing, and significantly higher in women in comparison with men. Adherence was generally high, only with higher levels in women for rivaroxaban. Persistence during the first year of treatment was also high in general, being significantly more persistent women than men in the case of dabigatran and edoxaban. Dose inadequacy, lack of adherence and of persistence can result in less effective and safe treatments. It is necessary to conduct studies analysing sex and gender differences in health and disease.
Source: Frontiers in Pharmacology - February 7, 2023 Category: Drugs & Pharmacology Source Type: research

RWD149 Reduction in Ischemic Stroke Rates in Patients With Non-Valvular Atrial Fibrillation During the Period 2013-2020: A Real-Life Study in Spain
The aim of this study is to analyze the variations in the incidence of cardiovascular events and mortality rates in patients with non-valvular atrial fibrillation (NVAF) receiving antithrombotic treatment (VKA, NOAC or antiplatelet drugs) between 2013 and 2020. In addition, this study estimates the impact of these variations in the use of healthcare resources and costs in Spain.
Source: Value in Health - December 1, 2022 Category: International Medicine & Public Health Authors: O Delgado, A Sicras-Mainar, I P érez Román, J Salazar, MI del Campo Alonso, A Echeto, D Vilanova, J Comin-Colet Source Type: research

Impact of heart failure on the clinical profile and outcomes in patients with atrial fibrillation treated with rivaroxaban. Data from the EMIR study
CONCLUSIONS: Among AF patients anticoagulated with rivaroxaban, HF patients had a worse clinical profile and a higher MACE risk and cardiovascular mortality. HF was independently associated with the development of MACE, but not with thromboembolic events or major bleeding.PMID:36200548 | DOI:10.5603/CJ.a2022.0091
Source: Cardiology Journal - October 6, 2022 Category: Cardiology Authors: Manuel Anguita S ánchez Francisco Mar ín Jaime Masjuan Juan Cos ín-Sales Jos é Manuel Vázquez Rodríguez Vivencio Barrios Gonzalo Bar ón-Esquivias I ñaki Lekuona Alejandro I P érez-Cabeza Rom án Freixa-Pamias Francisco Javier Parra Jimenez Mohame Source Type: research

Pages: 1  2  3  4  5  6  7