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Sex Differences in the Incidence and Outcomes of Newly Diagnosed Atrial Fibrillation-Related Stroke
Publication date: April 2018 Source:Canadian Journal of Cardiology, Volume 34, Issue 4 Author(s): J.D. Edwards, A. Micieli, A.Y.X. Yu, J. Fang, D. Gladstone
Source: Canadian Journal of Cardiology - March 21, 2018 Category: Cardiology Source Type: research

Creation and Implementation of an Outpatient Pathway for Atrial Fibrillation in the Emergency Department Setting: Results of an Expert Panel.
This article is protected by copyright. All rights reserved. PMID: 29524340 [PubMed - as supplied by publisher]
Source: Accident and Emergency Nursing - March 10, 2018 Category: Emergency Medicine Authors: Baugh CW, Clark CL, Wilson JW, Stiell IG, Kocheril AG, Luck KK, Myers TD, Pollack CV, Roumpf SK, Tomassoni GF, Williams JM, Patel BB, Wu F, Pines JM Tags: Acad Emerg Med Source Type: research

Creation and Implementation of an Outpatient Pathway for Atrial Fibrillation in the Emergency Department Setting: Results of an Expert Panel
This article is protected by copyright. All rights reserved.
Source: Academic Emergency Medicine - March 1, 2018 Category: Emergency Medicine Authors: Christopher W. Baugh, Carol L. Clark, Jason W. Wilson, Ian G. Stiell, Abraham G. Kocheril, Krista K. Luck, Troy D. Myers, Charles V. Pollack, Steven K. Roumpf, Gery F. Tomassoni, James M. Williams, Brian B. Patel, Fred Wu, Jesse M. Pines Tags: Special Contribution Source Type: research

Incident Atrial Fibrillation and Stroke in Patients with Atrial Flutter
Publication date: Available online 20 February 2018 Source:Canadian Journal of Cardiology Author(s): Jorge A. Wong, Jeff S. Healey
Source: Canadian Journal of Cardiology - February 20, 2018 Category: Cardiology Source Type: research

Direct factor Xa inhibitors for long-term stroke prevention in atrial fibrillation: could the lower dose fit all?
Publication date: Available online 7 February 2018 Source:Canadian Journal of Cardiology Author(s): Thomas A. Mavrakanas, Manish M. Sood
Source: Canadian Journal of Cardiology - February 7, 2018 Category: Cardiology Source Type: research

Stroke Prevention for High-Risk Atrial Fibrillation in the Emergency Setting: The Emergency Physician Perspective
Publication date: February 2018 Source:Canadian Journal of Cardiology, Volume 34, Issue 2 Author(s): Clare L. Atzema Atrial fibrillation is a frequent reason for presentation to an emergency department (ED), and the number of these visits are increasing. This creates an opportunity to improve the suboptimal rate of oral anticoagulation (OAC) use in patients with atrial fibrillation who are at high risk of stroke. However, there are very few data on whether OAC initiation in the ED, compared with referral to the longitudinal health care provider to initiate it, results in better long-term use. Moreover, for ethical and med...
Source: Canadian Journal of Cardiology - February 3, 2018 Category: Cardiology Source Type: research

Elevated Incidence of Atrial Fibrillation and Stroke in Patients with Atrial Flutter – A Population-Based Study
Conclusions Patients with isolated atrial flutter develop atrial fibrillation and stroke at a higher rate than the general population. Catheter ablation reduces but does not eliminate future AF incidence and stroke risk and continued anticoagulation after successful atrial flutter ablation may therefore be warranted. Teaser We examine the incidence of atrial fibrillation and stroke in a large real-world cohort of patients with atrial flutter, and the impact of atrial flutter ablation. Patients with atrial flutter developed atrial fibrillation and stroke at a higher rate than the general population. Atrial flutter ablation ...
Source: Canadian Journal of Cardiology - January 6, 2018 Category: Cardiology Source Type: research

Multiple thromboembolic events from a left atrial appendage occlusion device
We report a clinico-pathological case where thrombus adherent to an incompletely endothelialized Watchman® device resulted in multiple thromboembolic events, contributing to a fatal outcome. This case illustrates uncertainties regarding the device’s endothelialization process. Teaser Left atrial appendage occlusion devices are an alternative to oral anticoagulation in patients with nonvalvular atrial fibrillation at risk of ischemic stroke. Post-implantation thromboprophylaxis is recommended, but the optimal regimen is unknown. We report a clinico-pathological case where thrombus adherent to an incompletely endotheliali...
Source: Canadian Journal of Cardiology - December 27, 2017 Category: Cardiology Source Type: research

Assessment and management of the Left Atrial Appendage Thrombus in Patients with Nonvalvular Atrial Fibrillation
Conclusion Integration of clinical, biomarker, and imaging risk factors can improve overall prediction for the presence of LAA thrombi, translating into improved patient selection for imaging. The gold standard for the diagnosis of LAA thrombi remains TEE, although ICE, CCT, and CMR are promising alternative modalities. When LAA thrombi are discovered, the treatment regimen remains variable, although DOACs may have similar efficacy to VKA. Future trials will help further elucidate DOAC use for the treatment of LAA thrombi.
Source: Canadian Journal of Cardiology - December 15, 2017 Category: Cardiology Source Type: research

Mechanisms, Clinical Significance, and Prevention of Cognitive Impairment in Patients With Atrial Fibrillation
Publication date: December 2017 Source:Canadian Journal of Cardiology, Volume 33, Issue 12 Author(s): Lena Rivard, Paul Khairy Atrial fibrillation (AF) and dementia are major health issues, with growing evidence suggesting a consistent association between AF and all forms of dementia. Although dementia and AF share several risk factors, the association appears to be independent of a history of clinical stroke and other comorbidities such as hypertension, heart failure, and diabetes. Proposed mechanisms linking AF to cognitive decline include altered hemodynamics resulting in cerebral hypoperfusion, inflammation, genetic f...
Source: Canadian Journal of Cardiology - December 3, 2017 Category: Cardiology Source Type: research

The Relationship Between Cardiologist Care and Clinical Outcomes in Patients With New-Onset Atrial Fibrillation
Conclusions Cardiologist care was associated with a reduction in death in patients with new-onset AF. Further study to obtain a greater understanding of the processes of care associated with the observed survival improvement is warranted.
Source: Canadian Journal of Cardiology - December 3, 2017 Category: Cardiology Source Type: research

Mechanisms, Clinical Significance and Prevention of Cognitive Impairment in Atrial Fibrillation
Publication date: Available online 6 October 2017 Source:Canadian Journal of Cardiology Author(s): Lena Rivard, Paul Khairy Atrial fibrillation (AF) and dementia are major health issues, with growing evidence suggesting a consistent association between AF and all forms of dementia. Although dementia and AF share several risk factors, the association appears to be independent of a history of clinical stroke and other comorbidities such as hypertension, heart failure, and diabetes. Proposed mechanisms linking AF to cognitive decline include altered hemodynamics resulting in cerebral hypoperfusion, inflammation, genetic fact...
Source: Canadian Journal of Cardiology - October 7, 2017 Category: Cardiology Source Type: research

Chads2 score associated with atrial fibrillation but not predictive of stroke in adults with congenital heart disease
Publication date: October 2017 Source:Canadian Journal of Cardiology, Volume 33, Issue 10, Supplement Author(s): C. Tsui, D. Wan, J. Grewal, A. Barlow, M. Kiess, A. Krahn, D. Human, S. Chakrabarti, J. Sathananthan
Source: Canadian Journal of Cardiology - September 22, 2017 Category: Cardiology Source Type: research

Secondary prevention treatment after acute stroke in older South Asian, Chinese and other Canadians: a retrospective data analysis.
Abstract BACKGROUND: Little is known about whether there are differences in medication use between older patients of Chinese descent, those of South Asian descent and other Canadian patients after acute ischemic or primary intracerebral hemorrhagic stroke. The aim of this population-based study was to evaluate potential ethnic differences in secondary prevention pharmacotherapy after acute stroke. METHODS: Using health administrative data, we conducted a retrospective analysis of all patients aged 66 years or more admitted to hospital with acute stroke in Ontario (1997-2011) and British Columbia (1997-2009). ...
Source: cmaj - September 11, 2017 Category: General Medicine Authors: Khan NA, McAlister FA, Pilote L, Palepu A, Quan H, Hill MD, Fang J, Kapral MK Tags: CMAJ Open Source Type: research

Transcatheter vs Surgical Aortic Valve Replacement for Aortic Stenosis in Low-Intermediate Risk Patients: A Meta-analysis
Conclusions Although there was no difference in 30-day and late mortality, the rate of complications differed between TAVR and SAVR in the low-intermediate surgical risk population.
Source: Canadian Journal of Cardiology - August 25, 2017 Category: Cardiology Source Type: research

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