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The Connection Between Diabetes and Heart Arrhythmias
The human heart beats roughly 3 billion times during the course of an average lifetime. Every single time it beats, blood is drawn into its two upper chambers, held there briefly by a network of valves, and then pumped out forcefully through its two lower chambers. This drawing-and-pumping action ensures that about six liters of freshly oxygenated blood leaves the heart and enters the bloodstream every minute—a volume that can rise to more than 35 liters per minute when someone is exercising. [time-brightcove not-tgx=”true”] But none of that can happen unless the heart’s complicated machinery&md...
Source: TIME: Health - July 25, 2023 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized healthscienceclimate Source Type: news

Cardiovascular disease risk in paediatric and young adult non-alcoholic fatty liver disease
Conclusion Compared with matched population controls, children and young adults with biopsy-proven NAFLD had significantly higher rates of incident MACE, including ischaemic heart disease and congestive heart failure. Research to better characterise cardiovascular risk in children and young adults with NAFLD should be prioritised.
Source: Gut - February 7, 2023 Category: Gastroenterology Authors: Simon, T. G., Roelstraete, B., Alkhouri, N., Hagström, H., Sundström, J., Ludvigsson, J. F. Tags: Gut Hepatology Source Type: research

Detection of paroxysmal atrial fibrillation in 994 patients with a cerebrovascular event by intermittent 21-day ECG-monitoring and 7-day continuous Holter-recording
CONCLUSIONS: The two screening approaches had a similar yield of arrhythmia, in spite of the group with intermittent monitoring having a more favorable clinical profile. A positive screening was highly predictive of AF in ECG during the follow-up.PMID:35722185 | PMC:PMC9169544 | DOI:10.48101/ujms.v127.8318
Source: Upsala Journal of Medical Sciences - June 20, 2022 Category: General Medicine Authors: Johanna Pennlert M årten Rosenqvist Milos Kesek Source Type: research

Janssen Announces U.S. FDA Approval of PONVORY ™ (ponesimod), an Oral Treatment for Adults with Relapsing Multiple Sclerosis Proven Superior to Aubagio® (teriflunomide) in Reducing Annual Relapses and Brain Lesions
TITUSVILLE, N.J. – (March 19, 2021) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) approved PONVORY™ (ponesimod), a once-daily oral selective sphingosine-1-phosphate receptor 1 (S1P1) modulator, to treat adults with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease.1,2,3 PONVORY™ offers MS patients superior efficacy in reducing annualized relapse rates compared to an established oral therapy and a proven safety profile backed by ove...
Source: Johnson and Johnson - March 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Cost-effectiveness of dabigatran compared with warfarin for patients with atrial fibrillation in Sweden
Conclusion Dabigatran is a cost-effective treatment in Sweden, as its incremental cost-effectiveness ratio is below the normally accepted willingness to pay limit.
Source: European Heart Journal - January 14, 2013 Category: Cardiology Authors: Davidson, T., Husberg, M., Janzon, M., Oldgren, J., Levin, L.-A. Tags: Arrhythmia/electrophysiology Source Type: research