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Trends in Substance Abuse Preceding Stroke in Young Adults: An Update (S55.004)
Conclusions: Substance abuse is an important and highly prevalent risk factor for stroke in young adults. More efforts are needed to curb the increasing relationship between stroke in young adults and illicit drugs, alcohol, and smoking.Study supported by: NIH NINDS grant R01 NS30678Disclosure: Dr. De Los Rios La Rosa has nothing to disclose. Dr. Kleindorfer has received personal compensation for activities with Genentech, Inc. and for medicolegal case review. Dr. Khoury has nothing to disclose. Dr. Broderick has received research support from Significant, Genentech Inc., and Schering-Plough Corporation, and the National I...
Source: Neurology - April 9, 2014 Category: Neurology Authors: De Los Rios La Rosa, F., Kleindorfer, D., Khoury, J., Broderick, J., Alwell, K., Moomaw, C., Khatri, P., Adeoye, O., Flaherty, M., Woo, D., Eilerman, J., Ferioli, S., Kissela, B. Tags: Pediatric Stroke and Stroke in the Young Source Type: research

Risk factors and lesion localization correlations with post stroke depression (P7.131)
Conclusion: Probably, the pre-stroke psychological instability and stroke initial severity predisposes for post-stroke depression.Disclosure: Dr. Mataradze has nothing to disclose. Dr. Kherkheulidze has nothing to disclose. Dr. Beridze has nothing to disclose. Dr. Alphaidze has nothing to disclose. Dr. Eliauri has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Mataradze, S., Kherkheulidze, T., Beridze, M., Alphaidze, M., Eliauri, D. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke, Depression, and Anxiety Source Type: research

Primary prevention of stroke by a healthy lifestyle in a high-risk group
Conclusions: A healthy lifestyle is associated with a substantially reduced risk of stroke in men at higher risk of stroke.
Source: Neurology - June 1, 2015 Category: Neurology Authors: Larsson, S. C., Akesson, A., Wolk, A. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

Household Secondhand Smoke Exposure Confers Higher Stroke Risk and Poorer Stroke Prognosis (S42.005)
CONCLUSIONS: Household SHS is associated with a 1.5-fold increase in stroke risk and a 2-fold increase in mortality after stroke among never-smokers. While prospective studies are needed to assess causality, this study highlights the importance of obtaining SHS exposure history and counseling patients and their families on the potential impact of SHS on post-stroke outcomes.Disclosure: Dr. Lin has nothing to disclose. Dr. Ovbiagele has nothing to disclose. Dr. Markovic has nothing to disclose. Dr. Towfighi has nothing to disclose.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Lin, M., Ovbiagele, B., Markovic, D., Towfighi, A. Tags: Stroke Mechanism and Modifiers Source Type: research

Increasing stroke incidence and prevalence of risk factors in a low-income Chinese population
Conclusions: The incidence of stroke in rural China increased rapidly, particularly among middle-aged adults, along with a concurrent increase in risk factor prevalence. These findings suggest that without controlling these risk factors, stroke incidence will continue to increase over future decades in China.
Source: Neurology - January 26, 2015 Category: Neurology Authors: Wang, J., An, Z., Li, B., Yang, L., Tu, J., Gu, H., Zhan, C., Liu, B., Su, T.-C., Ning, X. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Incidence studies, Risk factors in epidemiology ARTICLE Source Type: research

Explanatory factors for the increased mortality of stroke patients with depression
Conclusion: Depression after stroke is associated with higher mortality, particularly among younger patients. Stroke survivors taking SSRIs have an increased mortality. The association between depression and mortality is not explained by other individual medical factors.
Source: Neurology - November 24, 2014 Category: Neurology Authors: Ayerbe, L., Ayis, S., Crichton, S. L., Rudd, A. G., Wolfe, C. D. A. Tags: All Cerebrovascular disease/Stroke, Depression, Cohort studies ARTICLE Source Type: research

Long-term disability after lacunar stroke: Secondary prevention of small subcortical strokes
Conclusions: In lacunar stroke patients, older age was associated with worsening long-term disability, even without recurrence. Worse long-term function was associated with diabetes, cognitive status, and prior stroke, and regional differences may be attributable to variations in health care delivery or scale interpretation.
Source: Neurology - March 9, 2015 Category: Neurology Authors: Dhamoon, M. S., McClure, L. A., White, C. L., Lakshminarayan, K., Benavente, O. R., Elkind, M. S. V., On behalf of the SPS3 Investigators Tags: All Cerebrovascular disease/Stroke, All Rehabilitation, All epidemiology ARTICLE Source Type: research

Effects of increasing IV tPA-treated stroke mimic rates at CT-based centers on clinical outcomes
Conclusions: Thrombolysis of stroke mimics is increasing at our CT-based spoke hospitals and not at our MRI-based hub hospitals. Caution should be used in interpreting clinical outcomes based on large stroke databases when stroke diagnosis at discharge is unclear. Inadvertent reporting of treated stroke mimics as strokes will artificially elevate overall favorable clinical outcomes with additional downstream costs to patients and the health care system.
Source: Neurology - July 24, 2017 Category: Neurology Authors: Burton, T. M., Luby, M., Nadareishvili, Z., Benson, R. T., Lynch, J. K., Latour, L. L., Hsia, A. W. Tags: Outcome research, CT, MRI, DWI, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Clinical profile, risk factors, etiology and outcome of stroke in young Filipino adults. (P7.147)
Conclusion - Stroke occurs at a younger age in Filipinos compared to other Asian and European countries. The incidence of stroke in young Filipinos were similar to Asian figures but higher compared to European studies. Hypertension is the most common risk factor in the world followed by diabetes mellitus and dyslipidemia. In Filipinos however, cultural vices such as smoking and alcoholism were the second and third leading risk factors. This paper to the best of our knowledge is the first to report the unique profile of stroke in young Filipino patients.Disclosure: Dr. Talamera has nothing to disclose. Dr. San Jose has noth...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Talamera, T. A., San Jose, M. C., Sanchez, J. A., Pascual IV, J. L. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

Moderate alcohol intake reduces risk of ischemic stroke in Korea
Conclusions: Our findings suggest that light to moderate distilled alcohol consumption may reduce the risk of ischemic stroke in Koreans.
Source: Neurology - November 30, 2015 Category: Neurology Authors: Lee, S. J., Cho, Y.-J., Kim, J. G., Ko, Y., Hong, K.-S., Park, J.-M., Kang, K., Park, T. H., Park, S.-S., Lee, K. B., Cha, J. K., Kim, D.-H., Lee, J., Kim, J.-T., Lee, J., Lee, J. S., Jang, M. S., Han, M.-K., Gorelick, P. B., Bae, H.-J., On behalf of the Tags: All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Case control studies ARTICLE Source Type: research

Serum matrix metalloproteinase-9 levels and prognosis of acute ischemic stroke
Conclusions: Higher serum MMP-9 levels in the acute phase of ischemic stroke were associated with increased risk of mortality and major disability, suggesting that serum MMP-9 could be an important prognostic factor for ischemic stroke.
Source: Neurology - August 21, 2017 Category: Neurology Authors: Zhong, C., Yang, J., Xu, T., Xu, T., Peng, Y., Wang, A., Wang, J., Peng, H., Li, Q., Ju, Z., Geng, D., Zhang, Y., He, J., For the CATIS Investigators Tags: Stroke prevention, Prognosis, All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Cohort studies ARTICLE Source Type: research

Racial differences in the Risk factors, Severity, Outcomes and Treatment in Acute Ischemic Stroke (P7.141)
Conclusion: Despite great disparity in both groups the outcomes were similar.Disclosure: Dr. Chauhan has nothing to disclose. Dr. Ali has nothing to disclose. Dr. Bianchi has nothing to disclose. Dr. Hinduja has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Chauhan, M. A., Ali, S., Bianchi, N., Hinduja, A. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

Healthy diet and lifestyle and risk of stroke in a prospective cohort of women
Conclusions: These findings indicate that a low-risk lifestyle can substantially reduce the risk of stroke, especially cerebral infarction.
Source: Neurology - November 3, 2014 Category: Neurology Authors: Larsson, S. C., Akesson, A., Wolk, A. Tags: All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

Impact of Vascular Risk factors on Hemorrhagic Transformation Following rt-PA Administration for Acute Ischemic Stroke (P4.269)
Conclusions:No vascular risk factor was independently associated with HT, suggesting a confounding effect from stroke severity (NIHSS score).Disclosure: Dr. Shaban has nothing to disclose. Dr. Tasneem has nothing to disclose. Dr. Dandapat has nothing to disclose. Dr. Ahmed has nothing to disclose. Dr. Policeni has nothing to disclose. Dr. Olalde has nothing to disclose. Dr. Samaniego has nothing to disclose. Dr. Shim has nothing to disclose. Dr. Pieper has nothing to disclose. Dr. Leira has nothing to disclose. Dr. Ortega-Gutierrez has nothing to disclose. Dr. Adams has nothing to disclose. Dr. Nagaraja has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Shaban, A., Tasneem, N., Dandapat, S., Ahmed, U., Policeni, B., Olalde, H., Samaniego, E., Shim, H., Pieper, C., Leira, E., Ortega-Gutierrez, S., Adams, H., Nagaraja, N. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Retinal and Ophthalmic Artery Studies in Ischemic Stroke Patients Using Fundus Photography and Transcranial Doppler Methods (P4.252)
Conclusions:Our study in a robust sample of non-severe stroke patients showed that abnormal retinal AVR is strongly associated with IS patients even after accounting for traditional risk factors. OA-TCD studies, on the other hand, did not have significant associations with stroke group.Disclosure: Dr. Patil has nothing to disclose. Dr. Narayan has nothing to disclose. Dr. Babu K has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Patil, K., Narayan, S., Babu, K. R. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

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