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Mp13: important role of prothrombin time (pt) and partial thromboplastin time (ptt) in predicting tpa-related hemorrhagic transformation
Conclusions Higher PT/PTT level within 72 hr of IV tPA is early marker of tPA-induced HT. Whether these routine labs have value in symptomatic hemorrhage will require further study in a larger cohort. But this proof-of-concept study suggests that tPA efficacy can potentially be followed in real time. The development of a reliable blood test would be of clinical utility to gauge thrombolytic efficacy in real time to guide and triage adjunct treatments. Abstract MP13 Figure 1
Source: Journal of Investigative Medicine - February 25, 2016 Category: Research Authors: Deng, W., Wickham, T., McMullin, D., Feeney, K., Buonanno, F., Lo, E., Ning, M. Tags: Moderated Poster, 11:45 PM - 1:05 PM, Wednesday, April 13, 2016 Source Type: research

Reversal of antithrombotic treatment in intracranial hemorrhage--A review of current strategies and guidelines.
Abstract In the last few years, there has been a rapid increase in patients being treated with various anticoagulation and antiplatelet agents. In clinical neurology, these drugs are administered for primary and secondary stroke prevention or to avoid the consequences of immobilization of severe stroke patients. Additionally, thrombolytic intravenous therapy and, recently, intra-arterial therapy for stroke have been increasingly employed all over the world. These therapies are associated with an increased risk of hemorrhage, including the most dangerous, intracranial hemorrhage. The knowledge of the standards for ...
Source: Neurologia i Neurochirurgia Polska - August 30, 2015 Category: Neurology Authors: Grzegorski T, Andrzejewska N, Kaźmierski R Tags: Neurol Neurochir Pol Source Type: research

P-013 initial experience with the ace and ace64 cerebral reperfusion catheters in the endovascular treatment of acute ischemic stroke
ConclusionIn our initial experience, the ACE/ACE64 reperfusion catheters provide a safe and effective tool for the treatment of acute ischemic stroke using direct aspiration, in which we were able to recanalize (TICI 2B/3) 96.4% of cases, achieving good clinical results.DisclosuresP. Navia: None. J. Massó: None. J. Larrea: None. E. Pardo: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Navia, P., Masso, J., Larrea, J., Pardo, E. Tags: SNIS 12th Annual Meeting Oral Poster Abstracts Source Type: research

Reversal of antithrombotic treatment in intracranial hemorrhage - A review of current strategies and guidelines.
Abstract In the last few years, there has been a rapid increase in patients being treated with various anticoagulation and antiplatelet agents. In clinical neurology, these drugs are administered for primary and secondary stroke prevention or to avoid the consequences of immobilization of severe stroke patients. Additionally, thrombolytic intravenous therapy and, recently, intra-arterial therapy for stroke have been increasingly employed all over the world. These therapies are associated with an increased risk of hemorrhage, including the most dangerous, intracranial hemorrhage. The knowledge of the standards for ...
Source: Neurologia i Neurochirurgia Polska - July 1, 2015 Category: Neurology Authors: Grzegorski T, Andrzejewska N, Kaźmierski R Tags: Neurol Neurochir Pol Source Type: research