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Specialty: Primary Care
Condition: Thrombosis

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Total 33 results found since Jan 2013.

Therapeutic Dilemma of Wake-up Stroke: Clinical and Brain Imaging Characteristics and Reperfusion as a Treatment Option
Conclusions: Only minor dissimilarities between clinical and radiologic features of WUS and clear-onset stroke were found. Circadian patterns of stroke onset were observed in both groups. Stroke was more likely to occur during waking than during sleep, and a diurnal pattern of common occurrence during the morning was documented. Recognition of the acceptable timeframe for acute reperfusion therapy in unwitnessed strokes is crucial so that thrombolytic treatment can be started for these patients.PMID:36441986 | DOI:10.4088/PCC.21m03216
Source: The Primary Care Companion for CNS Disorders - November 28, 2022 Category: Primary Care Authors: Erum Mubashir Shariff Fahd Ali Al Khmais Saima Nazish Noman Ishaque Aishah Ibrahim Al Bakr Reem S AlOmar Danah Aljaafari Mohammad AlShurem Azra Zafar Rizwana Shahid Sari AlSuhaibani Saeed Al-Jubran Nehad M Soltan Abdulaziz Mohammad Al-Sharydah Majed Alabd Source Type: research

Differences in the survival after an episode of stroke treated with thrombolytic therapy. Study Ebrictus.
CONCLUSIONS: After stroke episode treated with thrombolytic therapy, men have 12% higher risk of dying than women and don't be treated with secondary cardiovascular prevention rise 7.7 times the mortality risk. PMID: 24953174 [PubMed - as supplied by publisher]
Source: Atencion Primaria - June 18, 2014 Category: Primary Care Authors: Clua-Espuny JL, Ripolles-Vicente R, Lopez-Pablo C, Panisello-Tafalla A, Lucas-Noll J, Calduch-Noll C, González-Henares MA, Queralt-Tomas ML Tags: Aten Primaria Source Type: research

Older age and duration of exposure to type 2 diabetes in selective screening of asymptomatic carotid artery stenosis for primary stroke prevention —A single institution experience
Carotid artery disease is a well-known cause of stroke. In Malaysia, stroke is the third most common cause of death [1]. To our knowledge, there is still limited information regarding stroke and its associated risk factors. Strokes from ischemic infarction of the brain is due to narrowing or occlusion from local thrombosis or embolization of a proximal thrombus. The incidence of ischemic stroke from carotid artery stenosis in an asymptomatic western population is approximately 2.7% according to a report from Netherlands by Hartog et al.
Source: Primary Care Diabetes - November 16, 2019 Category: Primary Care Authors: Lenny Suryani Safri, Henry Tan Chor Lip, M. Iqbal Saripan, Tan Jih Huei, K. Krishna, Mohamad Azim Md Idris, Hanafiah Harunarashid Tags: Original research Source Type: research

The change of paradigm in stroke prevention in atrial fibrillation. Challenges and emerging opportunities for the family physician.
Abstract Atrial fibrillation (AF), is the most prevalent sustained arrhythmia in general population, affecting up to 10% in patients of advanced age. AF doubles overall mortality and increases up to 5-6 times the risk of stroke, which have the characteristic of being particularly harmfull. The basis of treatment on AF are the rhythm or rate control and the prevention of thromboembolism. For the latter purpose the treatments that have been most effective are oral acticoagulants. For decades and until just a few years ago, the only oral drugs available for this purpose have been the anti-vitamin K, mainly represente...
Source: Atencion Primaria - April 1, 2013 Category: Primary Care Authors: Castillo Rodríguez JC, Lozano IF Tags: Aten Primaria Source Type: research

Stroke: Initiative Cuts Time to tPA (CME/CE)
SAN DIEGO (MedPage Today) -- An effort to shorten the time between when patients with acute ischemic stroke arrive at the hospital and when they receive intravenous thrombolytic therapy -- the door-to-needle time -- proved successful, researchers found.
Source: MedPage Today Primary Care - February 17, 2014 Category: Primary Care Source Type: news

Effectiveness of Early Stroke Thrombolysis Confirmed in Community-Based Study (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and André Sofair, MD, MPH The effectiveness of early thrombolytic therapy after acute stroke observed in randomized trials persists in everyday clinical practice, according to a large, …
Source: Physician's First Watch current issue - June 3, 2014 Category: Primary Care Source Type: news

ISC: Imaging supplants clocks for targeting stroke reperfusion
LOS ANGELES – Can brain imaging surpass the clock for identifying acute ischemic stroke patients who will benefit from thrombolytic or thrombectomy treatment? That’s what experts now envision, based...
Source: Family Practice News - February 26, 2016 Category: Primary Care Source Type: news

A case of ischemic stroke and transient thrombocytopenia in a young female following adenoviral vector-based COVID-19 vaccination: Was the association incidental or causal?
We report a 23-year-old healthy female who developed seizures, altered sensorium, and left hemiparesis, 20 days after receiving the first dose of adenoviral vector-based COVID-19 vaccine "Covishield™." The patient had transient thrombocytopenia. The D-dimer level was 2460 ng/mL. Magnetic resonance imaging (MRI) demonstrated occlusion of M2 segment of the middle cerebral artery and cerebral infarction. Platelet factor-4 antibodies level was normal. Treatment with aspirin and antiepileptic drugs resulted in a remarkable recovery. This is the first Indian case report of ischemic stroke and transient thrombocytopenia followi...
Source: Primary Care - January 9, 2023 Category: Primary Care Authors: Shweta Pandey Ravindra Kumar Garg Pooja Tripathi Hardeep S Malhotra Neeraj Kumar Source Type: research

Approach to the new oral anticoagulants in family practice: Part 1: comparing the options.
CONCLUSION: The NOACs represent important alternatives in the management of patients with AF and VTE, especially for patients who have difficulty accessing regular coagulation monitoring. The companion to this article addresses common "what if" questions that arise in the long-term clinical follow-up and management of patients receiving NOACs. PMID: 25392438 [PubMed - as supplied by publisher]
Source: Canadian Family Physician Medecin de Famille Canadien - November 1, 2014 Category: Primary Care Authors: Douketis J, Bell AD, Eikelboom J, Liew A Tags: Can Fam Physician Source Type: research

Novel Anticoagulants in Atrial Fibrillation: A Primer for the Primary Physician
This article provides a review of recent published trials of the use of NOACs in atrial fibrillation. Practical points on indications, contraindications, mechanism of action, interactions, and perioperative management tips are discussed with a view toward the safe and effective use of these new medications. When patients are transitioned between different anticoagulant medications, the risks of thrombosis and bleeding need to be considered. When switching from warfarin to a NOAC, the NOAC can be started once the international normalized ratio is ≤2.0.
Source: Journal of the American Board of Family Medicine - July 7, 2015 Category: Primary Care Authors: Mookadam, M., Shamoun, F. E., Mookadam, F. Tags: Clinical Reviews Source Type: research

Anticoagulation: Updated Guidelines for Outpatient Management.
Abstract Anticoagulation therapy is recommended for preventing, treating, and reducing the recurrence of venous thromboembolism, and preventing stroke in persons with atrial fibrillation. Direct oral anticoagulants are first-line agents for eligible patients for treating venous thromboembolism and preventing stroke in those with nonvalvular atrial fibrillation. Vitamin K antagonists are recommended for patients with mechanical valves and valvular atrial fibrillation. Vitamin K antagonists inhibit the production of vitamin K-related factors and require a minimum of five days overlap with parenteral anticoagulants, ...
Source: American Family Physician - September 30, 2019 Category: Primary Care Authors: Wigle P, Hein B, Bernheisel CR Tags: Am Fam Physician Source Type: research

Combined hormonal contraception
Abstract: Combined oral contraception is now available as oral, transdermal, vaginal and injectable preparations. Only the pill and patch are currently marketed in the UK. Most of the data come from the oral preparation (the combined pill), which has been marketed for more than 40 years and used by millions of women. Used perfectly, combined hormonal contraception is highly effective (failure rate 1/1000), because it works by inhibiting ovulation. In typical use, however, mistakes are made, and pill failure rates are about 8%. Serious cardiovascular side-effects (heart attack, stroke and venous thromboembolism) are ra...
Source: Women's Health Medicine - November 1, 2006 Category: Primary Care Authors: Anna Glasier Source Type: research