Novel Anticoagulants in Atrial Fibrillation: A Primer for the Primary Physician

This article provides a review of recent published trials of the use of NOACs in atrial fibrillation. Practical points on indications, contraindications, mechanism of action, interactions, and perioperative management tips are discussed with a view toward the safe and effective use of these new medications. When patients are transitioned between different anticoagulant medications, the risks of thrombosis and bleeding need to be considered. When switching from warfarin to a NOAC, the NOAC can be started once the international normalized ratio is ≤2.0.

Source: Journal of the American Board of Family Medicine - July 7, 2015 Category: Primary Care Authors: Mookadam, M., Shamoun, F. E., Mookadam, F. Tags: Clinical Reviews Source Type: research