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Medically Attended Acute Adverse Events in Pregnant People After Coronavirus Disease 2019 (COVID-19) Booster Vaccination
Obstet Gynecol. 2023 May 11. doi: 10.1097/AOG.0000000000005241. Online ahead of print.ABSTRACTIn this multisite, observational, matched cohort study of more than 80,000 pregnant people, receipt of an mRNA monovalent coronavirus disease 2019 (COVID-19) booster vaccination in pregnancy was not associated with increased risk for thrombocytopenia, myocarditis, venous thromboembolism, ischemic stroke, or other serious adverse events within 21 or 42 days after booster vaccination. The mRNA monovalent COVID-19 booster in pregnancy was associated with an increased risk for medically attended malaise or fatigue within 7 days of vac...
Source: Obstetrics and Gynecology - May 11, 2023 Category: OBGYN Authors: Malini B DeSilva Jacob Haapala Gabriela Vazquez-Benitez Thomas G Boyce Candace C Fuller Matthew F Daley Darios Getahun Simon J Hambidge Heather S Lipkind Allison L Naleway Jennifer C Nelson Kimberly K Vesco Eric S Weintraub Joshua T B Williams Ousseny Zer Source Type: research

Coronavirus disease 2019 in pregnancy: consider thromboembolic disorders and thromboprophylaxis
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory distress syndrome coronavirus 2. This syndrome generally begins with respiratory symptoms that may progress to single-organ dysfunction (ie, respiratory failure) and then to multiorgan failure and death. In nonpregnant patients admitted to the intensive care unit with COVID-19 pneumonia, the frequency of venous thromboembolic disorders is 25% (20 of 81) detected by ultrasound examination of the lower extremities.1 In another series of 184 patients with confirmed COVID-19 pneumonia, 31% of patients had venous or arterial thromboembolism (defined as ac...
Source: American Journal of Obstetrics and Gynecology - April 21, 2020 Category: OBGYN Authors: Gian Carlo Di Renzo, Irene Giardina Tags: Letter to the Editors Source Type: research