Stroke RSS Page 2

Filtered By:
Specialty: Hematology
Condition: Thrombosis

This page shows you your search results in order of date. This is page number 2.

Order by Relevance | Date

Total 1625 results found since Jan 2013.

Sexual dimorphism in peripheral blood cell characteristics linked to recanalization success of endovascular thrombectomy in acute ischemic stroke
AbstractEndovascular thrombectomy (EVT) success to treat acute ischemic stroke varies with factors like stroke etiology and clot composition, which can differ between sexes. We studied if sex-specific blood cell characteristics (BCCs) are related to recanalization success. We analyzed electronic health records of 333 EVT patients from a single interve ntion center, and extracted 71 BCCs from the Sapphire flow cytometry analyzer. Through Sparse Partial Least Squares Discriminant Analysis, incorporating cross-validation and stability selection, we identified BCCs associated with successful recanalization (TICI 3) in ...
Source: Journal of Thrombosis and Thrombolysis - August 18, 2023 Category: Hematology Source Type: research

Metabolite signature in acute ischemic stroke thrombi: a systematic review
In conclusion, results of the present study show that the thrombi niche has a glycolytic phenotype. Future studies should work to better understand the metabolic properties of AIS thrombi.
Source: Journal of Thrombosis and Thrombolysis - August 14, 2023 Category: Hematology Source Type: research

Validating the predictive ability of the 2MACE score for major adverse cardiovascular events in patients with atrial fibrillation: results from phase II/III of the GLORIA-AF registry
AbstractThe 2MACE score was specifically developed as a risk-stratification tool in atrial fibrillation (AF) to predict cardiovascular outcomes. We evaluated the predictive ability of the 2MACE score in the GLORIA-AF registry. All eligible patients from phase II/III of the prospective global GLORIA-AF registry were included. Major adverse cardiac events (MACEs) were defined as the composite outcome of stroke, myocardial infarction and cardiovascular death. Cox proportional hazards were used to examine the relationship between the 2MACE score and study outcomes. Predictive capability of the 2MACE score was investigated usin...
Source: Journal of Thrombosis and Thrombolysis - August 11, 2023 Category: Hematology Source Type: research

Screening for clinically relevant drug-drug interactions between direct oral anticoagulants and antineoplastic agents: a pharmacovigilance approach
ConclusionNo signal of DDIs between DOACs and antineoplastic agents was detected, except for DOAC-neratinib. Most DDIs between DOACs and antineoplastic agents may not be clinically relevant. The DDIs between DOACs and neratinib should be further examined in future research.
Source: Journal of Thrombosis and Thrombolysis - August 10, 2023 Category: Hematology Source Type: research

Optimal anti-platelet therapy for older patients with acute coronary syndrome: a network meta-analysis of randomized trials comprising 59,284 older patients
AbstractThe aim of this study was to identify the optimal anti-platelet therapy in older acute coronary syndrome (ACS) patients with a mean age ≥ 60 years by comparing the efficacy and safety of different anti-platelet therapies. The selection of antiplatelet therapy in older patients with ACS is a clinical challenge. Numerous evidences indicate that the de-escalation of dual anti-platelet therapy (DAPT) or P2Y12 inhibitor monotherap y may reduce bleeding risk without increasing thrombotic events. However, there is a lack of systematic reviews and optimal strategy analysis regarding older ACS patients. Randomized co...
Source: Journal of Thrombosis and Thrombolysis - August 7, 2023 Category: Hematology Source Type: research

Outcomes in infants with unprovoked venous thromboembolism: A retrospective cohort study
CONCLUSION: There is a low rate of recurrent VTE but significant end-organ morbidity in infants with unprovoked VTE.PMID:37538506 | PMC:PMC10394551 | DOI:10.1016/j.rpth.2023.100174
Source: Thrombosis and Haemostasis - August 4, 2023 Category: Hematology Authors: Hilary Whitworth Lauren A Beslow Rebecca A Hubbard Charles E Leonard Rebecca Scobell Char Witmer Leslie Raffini Source Type: research

Thrombus composition and thrombolysis resistance in stroke
Res Pract Thromb Haemost. 2023 May 16;7(4):100178. doi: 10.1016/j.rpth.2023.100178. eCollection 2023 May.ABSTRACTA State of the Art lecture titled "Thrombus Composition and Thrombolysis Resistance in Stroke" was presented at the ISTH Congress in 2022. Intravenous thrombolysis (IVT) remains the only pharmacologic option to re-establish cerebral perfusion at the acute phase of ischemic stroke. IVT is based on the administration of recombinant tissue plasminogen activator with the objective of dissolving fibrin, the major fibrillar protein component of thrombi. Almost 30 years on from its introduction, although the clinical b...
Source: Thrombosis and Haemostasis - August 4, 2023 Category: Hematology Authors: Benoit Ho-Tin-No é Jean-Philippe Desilles Mikael Mazighi Source Type: research

Geographic variation in clinical outcomes and anticoagulation among medicare beneficiaries with non-valvular atrial fibrillation
AbstractOral anticoagulants (OACs) have been used to prevent stroke/systemic embolism (SE) among patients with non-valvular atrial fibrillation (NVAF). To evaluate baseline clinical characteristics, incidence rates of stroke/SE and hospitalization for bleeding, and OAC use among elderly patients with NVAF in the US by geographic region. Patients with NVAF were selected from the US Centers for Medicare& Medicaid Services claims database (01JAN2013-31DEC2016). Twelve months of health plan enrollment was required before and after the NVAF diagnosis to evaluate baseline characteristics and outcomes, respectively. Each pati...
Source: Journal of Thrombosis and Thrombolysis - August 2, 2023 Category: Hematology Source Type: research

Temporal trends in anticoagulation use and clinical outcomes among medicare beneficiaries with non-valvular atrial fibrillation
ConclusionsThe proportions of patients with non-valvular atrial fibrillation who were not prescribed an oral anticoagulant decreased but remained high. We observed an increase in direct oral anticoagulant use that coincided with decreased incidence of clinical outcomes as well as decreasing total healthcare costs.
Source: Journal of Thrombosis and Thrombolysis - August 2, 2023 Category: Hematology Source Type: research

Real world time trends in antithrombotic treatment for newly diagnosed atrial fibrillation in China: reports from the GLORIA-AF Phase III registry
Stroke prevention with oral anticoagulant (OAC) therapy, including non-vitamin K antagonist oral anticoagulants (NOACs), is recommended in patients with atrial fibrillation (AF). This analysis describes the an...
Source: Thrombosis Journal - August 1, 2023 Category: Hematology Authors: Xiaoxia Liu, Guoze Feng, Sabrina Vogel Marler, Menno V Huisman, Gregory Y. H. Lip and Changsheng Ma Tags: Research Source Type: research

D-dimer to fibrinogen ratio predicts early neurological deterioration in ischemic stroke with atrial fibrillation
The D-dimer to fibrinogen ratio (DFR) is a good indicator of clot-producing activity in thrombotic disease, but its clinical usefulness in stroke patients with nonvalvular atrial fibrillation (NVAF) has not been studied. We evaluated the association between the DFR and early neurological deterioration (END) in acute ischemic stroke (AIS) patients with NVAF.
Source: Thrombosis Research - July 31, 2023 Category: Hematology Authors: Ki-Woong Nam, Chi Kyung Kim, Sungwook Yu, Kyungmi Oh, Jong-Won Chung, Oh. Young Bang, Gyeong-Moon Kim, Jin-Man Jung, Tae-Jin Song, Yong-Jae Kim, Bum Joon Kim, Sung Hyuk Heo, Kwang-Yeol Park, Jeong-Min Kim, Jong-Ho Park, Jay Chol Choi, Man-Seok Park, Joon- Tags: Full Length Article Source Type: research

Pages: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20