Stroke RSS Page 16

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Specialty: Hematology
Condition: Thrombosis

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Total 1625 results found since Jan 2013.

Over-transfusion with blood for suspected hemorrhagic shock is not associated with worse clinical outcomes
DISCUSSION: Early empiric RBC transfusion for presumed hemorrhagic shock may subject patients to potential over-transfusion and end-organ damage. Among patients meeting clinical triggers for MTP, 1-3 units of allogeneic RBCs is not associated with worse outcomes.PMID:35753037 | DOI:10.1111/trf.16978
Source: Transfusion - June 26, 2022 Category: Hematology Authors: Rondi B Gelbard Russell L Griffin Lindy Reynolds Peter Abraham Jeffrey Warner Parker Hu Jeffrey D Kerby Rindi Uhlich Marisa B Marques Jan O Jansen John B Holcomb Source Type: research

Safety and efficacy of endovascular thrombectomy in acute ischemic stroke treated with anticoagulants: a systematic review and meta-analysis
Endovascular thrombectomy (EVT) is an effective therapy in acute ischemic stroke (AIS) with large vessel occlusion, especially for those who are unsuitable for intravenous thrombolysis. However, the safety and...
Source: Thrombosis Journal - June 21, 2022 Category: Hematology Authors: Jia-Hung Chen, Chien-Tai Hong, Chen-Chih Chung, Yi-Chun Kuan and Lung Chan Tags: Research Source Type: research

DNA Methylation and Ischemic Stroke Risk: An Epigenome-Wide Association Study
CONCLUSION: Specific DNA methylation pattern is causally associated with IS risk. These results could be useful for specifically predicting stroke occurrence and could potentially be evaluated as therapeutic targets.PMID:35717949 | DOI:10.1055/s-0042-1749328
Source: Thrombosis and Haemostasis - June 19, 2022 Category: Hematology Authors: Natalia Cullell Carolina Soriano-T árraga Cristina Gallego-F ábrega Jara C árcel-Márquez Nuria P Torres- Águila Elena Mui ño Miquel Lled ós Laia Lluci à-Carol Manel Esteller Manuel Castro de Moura Joan Montaner Alba Fern ández-Sanlés Roberto Elo Source Type: research

Intravenous thrombolysis and endovascular thrombectomy for acute ischaemic stroke in patients with Moyamoya disease - a systematic review and meta-summary of case reports
ConclusionsIn this systematic review and meta-summary, the utility of IVT and ET in MMD-associated AIS appears feasible in selected cases. Further larger cohort studies are required to evaluate these treatment approaches.Highlights· AIS in MMD was typically managed with bypass surgery but not via thrombolysis or thrombectomy.· In this meta-summary, all patients treated with thrombolysis and/or thrombectomy survived and some experienced symptomatic and/or functional improvement.· Further larger cohort studies are necessary for investigating the role of thrombolysis and/or thrombectomy as treatment of AIS in MMD.
Source: Journal of Thrombosis and Thrombolysis - June 14, 2022 Category: Hematology Source Type: research

Rivaroxaban Underdose for Atrial Fibrillation with Stable Coronary Disease: The AFIRE Trial Findings
CONCLUSION: In patients with AF, stable CAD, and preserved renal function, rivaroxaban underdose was associated with similar rates of thrombotic events but a lower incidence of hemorrhagic events than the standard dose.CLINICAL TRIAL REGISTRATION: AFIRE UMIN Clinical Trials Registry (https://www.umin.ac.jp/ctr/), number UMIN000016612, and ClinicalTrials.gov, number NCT02642419.PMID:35697255 | DOI:10.1055/s-0042-1744543
Source: Thrombosis and Haemostasis - June 13, 2022 Category: Hematology Authors: Hiroyuki Arashi Junichi Yamaguchi Nobuhisa Hagiwara Satoshi Yasuda Koichi Kaikita Masaharu Akao Junya Ako Tetsuya Matoba Masato Nakamura Katsumi Miyauchi Kazuo Kimura Atsushi Hirayama Kunihiko Matsui Hisao Ogawa Source Type: research

Comparison of risk of serious cardiovascular events after haemorrhagic versus ischaemic stroke: a population-based study
CONCLUSIONS: The risk of subsequent cardiovascular events is similar between patients with incident haemorrhagic or ischaemic stroke. Patients with previous haemorrhagic stroke should be regarded as a population at very-high risk of subsequent CVD.PMID:35688459 | DOI:10.1055/a-1873-9092
Source: Thrombosis and Haemostasis - June 10, 2022 Category: Hematology Authors: Ralph Kwame Akyea Georgios Georgiopoulos Barbara Iyen Joe Kai Nadeem Qureshi George Ntaios Source Type: research

Adverse Events and All-Cause Mortality in Danish Patients with Cerebral Venous Thrombosis: A Nationwide Cohort Study
CONCLUSION: Intracranial bleeding, ischemic stroke, and mortality risks were higher for patients with CVT than matched patients with VTE and the general population, particularly within 6 months after diagnosis.PMID:35688451 | DOI:10.1055/s-0042-1743473
Source: Thrombosis and Haemostasis - June 10, 2022 Category: Hematology Authors: Anne Gulbech Ording Flemming Skj øth S øren Due Andersen Torben Bjerregaard Larsen Source Type: research

Immunity in Stroke: The Next Frontier
Thromb Haemost. 2022 Jun 10. doi: 10.1055/s-0042-1748890. Online ahead of print.ABSTRACTTranslational stroke research has long been focusing on neuroprotective strategies to prevent secondary tissue injury and promote recovery after acute ischemic brain injury. The inflammatory response to stroke has more recently emerged as a key pathophysiological pathway contributing to stroke outcome. It is now accepted that the inflammatory response is functionally involved in all phases of the ischemic stroke pathophysiology. The immune response is therefore considered a breakthrough target for ischemic stroke treatment. On one side,...
Source: Thrombosis and Haemostasis - June 10, 2022 Category: Hematology Authors: Ting Li Arthur Liesz Source Type: research

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