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Alcohol Consumption and Cerebral Small- and Large-Vessel Diseases: A Mendelian Randomization Analysis
CONCLUSIONS: Our findings suggest a positive association of alcohol consumption with risk of cerebral SVDs and its inverse association with risk of large-vessel disease through intermediaries, such as hypertension or low-density lipoprotein cholesterol. These findings provide insight into potential causal mechanisms linking alcohol consumption with stroke risk.PMID:37612092 | DOI:10.5551/jat.64222
Source: Journal of Atherosclerosis and Thrombosis - August 23, 2023 Category: Cardiology Authors: Takashi Hisamatsu Yasuharu Tabara Aya Kadota Sayuki Torii Keiko Kondo Yuichiro Yano Akihiko Shiino Kazuhiko Nozaki Tomonori Okamura Hirotsugu Ueshima Katsuyuki Miura SESSA Research Group Source Type: research

Imaging features of vertebrobasilar dolichoectasia combined with posterior circulation ischemic stroke: A vessel wall magnetic resonance imaging study
CONCLUSIONS: This preliminary study suggests that atherosclerosis may be an important cause of stroke in VBD patients. Symptomatic plaques in VBD patients have a lower degree of stenosis, NWI, and RI than that in non-VBD patients. VW-MRI may help to assess stroke mechanisms and identify VBD patients at high risk.PMID:37506476 | DOI:10.1016/j.ejrad.2023.110971
Source: Atherosclerosis - July 28, 2023 Category: Cardiology Authors: Fang Wu Miao Zhang Zhigang Qi Qingfeng Ma Zhipeng Yu Jie Lu Source Type: research

High-Resolution Magnetic Resonance Imaging of Acute Intracranial Artery Thrombus
CONCLUSIONS: HR-MRI helps clarify the pathogenesis of acute intracranial artery thrombus. The presence of peri-thrombus plaque and distal residual flow beyond the thrombus favor the stroke mechanism of atherosclerosis rather than cardioembolism.PMID:37452734 | DOI:10.1111/ene.15985
Source: Atherosclerosis - July 15, 2023 Category: Cardiology Authors: Zong-Mu-Yu Zhang Qian-Qian Si Hui-Sheng Chen Yi Yang Meng Zhang Shi-Wen Wu Yao Meng Ming-Li Li Qian-Qian Lin David S Liebeskind Yi-Ning Huang Wei-Hai Xu Source Type: research

EXPRESS: Magnetic resonance imaging for diagnostic workup of Embolic Stroke of Undetermined Source: a systematic review
CONCLUSION: MRI techniques allow to identify additional cardiac and vascular embolic sources and may further decrease the prevalence of patients with the diagnosis of ESUS.PMID:37435743 | DOI:10.1177/17474930231189946
Source: Atherosclerosis - July 12, 2023 Category: Cardiology Authors: Natallia Khenkina Alberto Aimo Iacopo Fabiani Pier Giorgio Masci Dimitrios Sagris Steven E Williams George Mavraganis Hui-Sheng Chen Max Wintermark Patrik Michel George Ntaios George Georgiopoulos Source Type: research

JAK2 V617F Mutation and Large Cerebral Artery Disease in Patients with Myeloproliferative Neoplasms
CONCLUSIONS: This study revealed a significant association between the JAK2 V617F mutation and LCAD in patients with MPNs. This suggests that the JAK2 V617F mutation may promote cerebrovascular atherosclerosis and could be very important in determining therapeutic strategies for patients with not only JAK2 V617F-mutated MPNs but also LCAD-related stroke.PMID:37344447 | DOI:10.5551/jat.64118
Source: Journal of Atherosclerosis and Thrombosis - June 21, 2023 Category: Cardiology Authors: Naoki Oyama Takanori Iwamoto Keito Doyu Saki Miyazato Tomoko Okazaki Seiko Yamada Toshinori Kondo Hideho Wada Yoshiki Yagita Source Type: research

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