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The effect of nicorandil on cardiac function and clinical outcomes in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: a randomised trial
CONCLUSIONS: Treatment with nicorandil for 6 months after primary PCI was not associated with any improvement in infarct size, CMR-determined cardiac function, and outcomes in STEMI patients.PMID:36942830 | DOI:10.1080/00015385.2022.2129592
Source: Acta Cardiologica - March 21, 2023 Category: Cardiology Authors: Jeong Cheon Choe Jun-Hyok Oh Han Cheol Lee Ji Won Lee Tae Sik Park Jong Ha Park La Eun Kim Min Su Kim Jinhee Ahn Jin Sup Park Hye Won Lee Jung Hyun Choi Kwang Soo Cha Source Type: research

A Non-Linear Role of Hyperlipidemia on Progression of Intracranial Atherosclerotic Plaques and Acute Downstream Ischemic Events
CONCLUSIONS: LDL was related with ischemia events in intermediate stage of intracranial atherosclerotic plaque progression, an excellent period for intensive lipid-lowering treatment. In advanced stage, inflammatory agents maybe the main contributor to ischemic events.PMID:36709996 | DOI:10.5551/jat.63971
Source: Journal of Atherosclerosis and Thrombosis - January 29, 2023 Category: Cardiology Authors: Jianxia Ke Jinrui Li Junting Chen Chengze Lai Weicheng Zheng Xiaoli Fu Xuewen Fang Lianxian Guo Zhu Shi Source Type: research

High Mean Platelet Volume Is Associated with Cerebral White Matter Hyperintensities in Non-Stroke Individuals
CONCLUSION: We found that high MPV level is independently associated with cerebral WMH. This result suggests that platelet activation plays a role in the development of cerebral WMH.PMID:36579377 | DOI:10.3349/ymj.2022.0368
Source: Atherosclerosis - December 29, 2022 Category: Cardiology Authors: Jung-Won Choi Kee Ook Lee Ye-Ji Jang Hyun-Kyung Kim Taeho Seo Yoo Jeong Roh Seung-Ook Choo Seung-Hun Oh Source Type: research

Relationship between Serum Irisin Levels and MRI-Measured Cerebral Small Vessel Disease in Japanese Men
CONCLUSIONS: Serum irisin levels were associated with less burden of total CSVD in healthy Japanese men. Serum irisin levels were also related with a reduced risk of PVHs, LIs, and CMBs, but not DSWMHs.PMID:36384910 | DOI:10.5551/jat.63824
Source: Journal of Atherosclerosis and Thrombosis - November 17, 2022 Category: Cardiology Authors: Mohammad Moniruzzaman Aya Kadota Takashi Hisamatsu Hiroyoshi Segawa Keiko Kondo Sayuki Torii Naoko Miyagawa Akira Fujiyoshi Yuichiro Yano Yoshiyuki Watanabe Akihiko Shiino Kazuhiko Nozaki Hirotsugu Ueshima Katsuyuki Miura SESSA Research Group Source Type: research

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