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Total 15499 results found since Jan 2013.

Cardiovascular and renal outcomes in patients with atrial fibrillation and stage 4 –5 chronic kidney disease receiving direct oral anticoagulants: a multicenter retrospective cohort study
AbstractThe role of direct oral anticoagulants (DOAC) in patients with atrial fibrillation (AF) and stage 4 –5 chronic kidney disease (CKD) is controversial. Electronic medical records from 2012 to 2021 were retrieved for patients with AF and stage 4–5 CKD receiving oral anticoagulants. Patients were separated into those receiving DOACs (dabigatran, rivaroxaban, apixaban, or edoxaban) or vitamin K ant agonists (VKA). Primary outcomes included ischemic stroke (IS), systemic thrombosis (SE), major bleeding, gastrointestinal bleeding, hemorrhagic stroke, acute myocardial infarction, cardiovascular death, and all-cause dea...
Source: Journal of Thrombosis and Thrombolysis - August 21, 2023 Category: Hematology Source Type: research

P135/313 Predictive value of CT head and CT angiogram in identifying ICAD associated large vessel occlusion
ConclusionOur findings suggest a significant association between the absence of the hyperdense artery sign and the presence of tapering at the occlusion site with ICAD in patients with LVO. Incorporating these signs in pre-thrombectomy evaluation has the potential to improve stroke care.Disclosure of InterestDr. Joe Leyon has/had consultancy agreements with Microvention Terumo, Medtronic, and Stryker Neurovascular.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Hassan, A., Leyon, J., Kaya, A. Tags: 2.1 ISCHEMIC - Logistics Source Type: research

P151/175 Direct aspiration with EMBOVAC - first clinical experience and clot composition (results the "PERFECT study)
ConclusionThis is the first clinical evaluation of EMBOVAC. Direct aspiration with EMBOVAC as first line therapy resulted in high rates of reperfusion and favorable clinical outcomes. Clot composition analysis can aid in better understanding of the stroke etiology and means for effective clot removal.Disclosure of InterestAcandis (OJ, CL, JF); Microvention (GM, CC, JF); Stryker (GM, CC, JF); Medtronic (GM, CC, JF); Surge2surgery (BG); MIVI (CC); Phenox (CL, JF); Penumbra (CL, JF); GSK (AS); German Ministry of Science & Education and Economy & Innovation, EU, Hamburgische Investitions-/Förderbank, Philips, B...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Lobotesis, K., Jansen, O., Marnat, G., Gory, B., Nordmeyer, H., Eckert, B., Alessandro, P., Cognard, C., Loehr, C., Bracco, S., Schaefer, A., Macera, A., Fiehler, J., Doyle, K., Piano, M. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P164/236 Antithrombotic regimen in emergent carotid stenting for acute ischemic stroke due to tandem lesion: a meta-analysis of aggregate data
ConclusionsIn AIS due to tandem occlusion, the periprocedural antithrombotic regimen of eCAS seems to have a marginal effect on good functional outcome. Overall, high intensity antithrombotic therapy may provide a marginal benefit on good functional outcome and carotid stent patency without a significant increase in risk of sICH.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Diana, F., Abdalkader, M., Behme, D., Li, W., Maurer, C. J., Pop, R., Hwang, Y.-H., Bartolini, B., Ros, V. D., Bracco, S., Cirillo, L., Marnat, G., Katsanos, A., Kaesmacher, J., Fischer, U., Sousa, D. A. d., Peschillo, S., Zini, A., Tomasello, A., Ribo, M Tags: 2.3 ISCHEMIC - Treatment Source Type: research

O21/183 Stenting of intracranial stenosis with the fibrin-heparin coated Credo heal stent -multicenter experience
ConclusionThe Credo heal stent offers a treatment option for patients with sICAD or with persistent occlusion. The rate of restenosis is low compared to previous trials. Its effectiveness with regard to long-term ischemic complications will be evaluated in the prospective ReCHRUT trial.Disclosure of InterestHannes Nordmeyer and Franziska Dorn received speaker honoraria from Acandis. All other author have nothing to disclose.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Nordmeyer, H., Dorn, F., Leo, V., Mousa, Z. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

O37/346 Endovascular treatment of cerebral venous thrombosis: a single center experience
ConclusionSince the advent of EVT for the AIS, the improvement of the devices and the endovascular techniques have increased, opening a new scenario for the treatment of the CVT in terms of efficacy and safety.Our study add evidence on the safety and efficacy of the endovascular techniques in the treatment of CVT.Disclosure of Interestnothing to disclose.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Piano, M., Macera, A., Cervo, A., Vitiello, A., Lozupone, E., Pero, G. Tags: 3.3 OTHER - Miscellaneous Source Type: research

P012/110 Flow diversion in a giant fusiform M2 aneurysm: very delayed parent vessel occlusion and post-thrombectomy re-in-stent thrombosis
ConclusionVery delayed in-stent thrombosis and subsequent parent vessel occlusion can occur after flow diversion procedures.Disclosure of InterestAK: Nothing to discloseMB: Consultant for Microvention, Cerenovus, Acandis, and RapidJF: The Co-author reports personal fees from Consultant for Acandis, Cerenovus, Medtronic, Microvention, Phenox, Penumbra, Roche, Tonbridge outside of the submitted work. He is a member of the Executive Board of the scientific societies DGNR and the President of ESMINT and holds Stock in Vastrax LLC and Tegus.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Kyselyova, A. A., Fiehler, J., Bester, M. Tags: 4.3 CASE PROPOSAL - Acute ischemic stroke Source Type: research

P014/130 Treatment of recurrent intracranial atherosclerotic disease-related stroke due to in-stent thrombosis with the CREDO(R) heal stent: A case report
ConclusionThis case highlights that re-stenting a recurrent ICAD-related stroke using the CREDO® heal stent is technically feasible, safe, and may improve clinical outcomes.Disclosure of InterestNothing to disclose.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Nguyen, A., Schulze-Zachau, V., Psychogios, M. Tags: 4.3 CASE PROPOSAL - Acute ischemic stroke Source Type: research

Stroke with large vessel occlusion in the posterior circulation: IV thrombolysis plus thrombectomy versus IV thrombolysis alone
AbstractEfficacy and safety of mechanical thrombectomy (MT) for stroke with posterior circulation large vessel occlusion (LVO) is still under debate. We aimed to compare the outcomes of stroke patients with posterior circulation LVO treated with intravenous thrombolysis (IVT) (< 4.5 h after symptom onset) plus MT < 6 h after symptom onset with those treated with IVT alone (< 4.5 h after symptom onset). Patients enrolled in the Italian Registry of Endovascular Treatment in Acute Stroke (IRETAS) and in the Italian centers included in the SITS-ISTR were analysed. We identified 409 IRETAS patients treate...
Source: Journal of Thrombosis and Thrombolysis - August 19, 2023 Category: Hematology Source Type: research

Low bleeding acceptance is associated with increased death risk in patients with atrial fibrillation on oral anticoagulation
AbstractBleeding is the most feared complication of anticoagulation. We sought to investigate whether the bleeding risk acceptance has a prognostic value during long-term follow-up in the era of direct oral anticoagulants (DOACs) among patients with atrial fibrillation (AF). We studied 167 consecutive AF outpatients [aged 68.8 SD 10.6 years; 141 (84.4%) on DOACs]. The bleeding acceptance was assessed based on the Bleeding Ratio defined as the declared maximum number of major bleedings that a patient would be willing to accept to prevent one major stroke. We recorded cerebrovascular ischemic events, major or clinically rele...
Source: Journal of Thrombosis and Thrombolysis - August 19, 2023 Category: Hematology Source Type: research

Effect of teleconsultation on the application of thrombolytic therapy in stroke patients in the emergency department
ConclusionsTeleconsultation was a successful and reliable strategy in assessing patients with ischemic stroke and making decisions for IV-tPA. Moreover, patient assessment via teleconsultation was less time consuming. The results of the study are promising for the use of teleconsultation in the future.
Source: Irish Journal of Medical Science - August 19, 2023 Category: General Medicine Source Type: research

Acute ischemic stroke: The role of emergency carotid endarterectomy in isolated extracranial internal carotid artery occlusion
CONCLUSIONS: Emergency CEA in isolated eICA occlusion has proved to be a safe and effective treatment option in selected patients. CT perfusion, imaging the ischemic penumbra and quantifying the tissue suitable for reperfusion, offers a valid support in the diagnostic-therapeutic workup. Indeed, we can infer that the area of the ischemic penumbra is directly proportional to the margin of clinical improvement after revascularization, supposing that the appropriate intervention timing is respect.PMID:37594376 | DOI:10.1177/17085381231192712
Source: Vascular - August 18, 2023 Category: Surgery Authors: Pierfilippo Acciarri Alice Camagni Maddalena Bressan Gladiol Zenunaj Ilaria Casetta Andrea Bernardoni Vincenzo Gasbarro Luca Traina Source Type: research

Herpes Zoster Ophthalmicus Discovered During Pain Consult Possibly Complicated With Dural Sinus Thrombosis and Refractory Headache Managed With Ketamine: A Case Report
In this report, we present the case of a 51-year-old male with severe headache and imaging findings of dural sinus thrombosis. He was later diagnosed with herpes zoster ophthalmicus and required aggressive inpatient management of neuropathic pain. Despite appropriate treatment, acute herpes zoster can progress to post-herpetic neuralgia, requiring long-term pain management.PMID:37593290 | PMC:PMC10430885 | DOI:10.7759/cureus.42018
Source: Herpes - August 18, 2023 Category: Infectious Diseases Authors: Laura Furtado Pessoa de Mendonca Alejandro Hallo-Carrasco Christian C Prusinski Christine Hunt Source Type: research

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