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Total 15499 results found since Jan 2013.

Oral Anticoagulation Use and Left Atrial Appendage Occlusion in LAAOS III
CONCLUSIONS: The benefit of LAA occlusion was consistent whether patients were receiving OACs or not. LAA occlusion provides thromboembolism reduction in patients independent of OAC use.PMID:37732457 | DOI:10.1161/CIRCULATIONAHA.122.060315
Source: Circulation - September 21, 2023 Category: Cardiology Authors: Stuart J Connolly Jeff S Healey Emilie P Belley-Cote Kumar Balasubramanian Domenico Paparella Katheryn Brady Wilko Reents Bernhard C Danner P J Devereaux Mukul Sharma Chinthanie Ramasundarahettige Salim Yusuf Richard P Whitlock Source Type: research

Impact of prior bariatric surgery on outcomes of hospitalized patients with systemic lupus erythematosus: a propensity score-matched analysis of the U.S. nationwide inpatient sample
CONCLUSIONS: Prior bariatric surgery is associated with favorable in-hospital outcomes in hospitalized patients with SLE and decreased likelihood for several SLE-related complications.PMID:37735043 | DOI:10.1016/j.soard.2023.06.006
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - September 21, 2023 Category: Surgery Authors: Po-Chun Wang Kung-Chan Ho Wen-Ching Ko Wei-Ning Lin Source Type: research

A comparative study of thoracoscopic left atrial appendage clipping versus stapled resection
CONCLUSIONS: The clipping group demonstrated a higher rate of complete LAA closure compared to the stapled resection group. Close monitoring of patients with residual LAA stumps is essential. Further research with larger cohorts is needed to elucidate impact of residual LAA stump on thromboembolic events.PMID:37734642 | DOI:10.1016/j.athoracsur.2023.09.010
Source: The Annals of Thoracic Surgery - September 21, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Suk Kyung Lim Chu Hyun Kim Ki Hong Choi Joong Hyun Ahn Young Keun On Sung Mok Kim Dong Seop Jeong Source Type: research

French National Diagnostic and Care Protocol for antiphospholipid syndrome in adults and children
Rev Med Interne. 2023 Sep 19:S0248-8663(23)00711-7. doi: 10.1016/j.revmed.2023.08.004. Online ahead of print.ABSTRACTAntiphospholipid syndrome (APS) is a chronic autoimmune disease involving vascular thrombosis and/or obstetric morbidity and persistent antibodies to phospholipids or certain phospholipid-associated proteins. It is a rare condition in adults and even rarer in children. The diagnosis of APS can be facilitated by the use of classification criteria based on a combination of clinical and biological features. APS may be rapidly progressive with multiple, often synchronous thromboses, resulting in life-threatening...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Z Amoura B Bader-Meunier C Bal Dit Sollier A Belot Y Benhamou H Bezanahary F Cohen N Costedoat-Chalumeau L Darnige L Drouet E Elefant A Harroche M Lambert T Martin I Martin-Toutain A Mathian A Mekinian M Pineton De Chambrun L de Pontual D Wahl C Yelnik S Source Type: research

Low value of inherited thrombophilia testing among patients with stroke or transient ischemic attack: A three-year retrospective study
Inherited thrombophilia testing in the acute inpatient setting is controversial and expensive, and rarely changes clinical management. We evaluated ordering patterns and results of inpatient inherited thrombophilia testing for patients who presented with an isolated acute ischemic stroke or transient ischemic attack (TIA) without concurrent venous thromboembolism.
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2023 Category: Neurology Authors: Shyam Majmundar, Sameep Thapa, Elan S. Miller, Rodney Bell, Robin Dharia, Diana Tzeng, Shaista Alam, Ruben Rhoades Source Type: research

Short Versus Long Duration of Dual Antiplatelet Therapy After Second-Generation Drug-Eluting Stents Implantation in Patients with Diabetes
CONCLUSION: This meta-analysis showed no statistically significant benefit of longer DAPT over shorter DAPT therapy in patients undergoing PCI with drug-eluting stent in patients with diabetes.PMID:37713685 | DOI:10.1097/MJT.0000000000001519
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Manesh Kumar Gangwani Muhammad Aziz Paul Chacko Asif Mahmood Muhammad Ali Fnu Priyanka Siraj Munir Abeer Aziz Shazib Sagheer Wade Lee-Smith Om Parkash Devesh Rai Bipul Baibhav Wilbert S Aronow Source Type: research

Oral microbiome mediated inflammation, a potential inductor of vascular diseases: a comprehensive review
Front Cardiovasc Med. 2023 Aug 30;10:1250263. doi: 10.3389/fcvm.2023.1250263. eCollection 2023.ABSTRACTThe dysbiosis of the oral microbiome and vascular translocation of the periodontopathic microorganism to peripheral blood can cause local and systemic extra-oral inflammation. Microorganisms associated with the subgingival biofilm are readily translocated to the peripheral circulation, generating bacteremia and endotoxemia, increasing the inflammation in the vascular endothelium and resulting in endothelial dysfunction. This review aimed to demonstrate how the dysbiosis of the oral microbiome and the translocation of oral...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Diego F Gualtero Gloria In és Lafaurie Diana Marcela Buitrago Yormaris Castillo Paula Katherine Vargas-Sanchez Diana Marcela Castillo Source Type: research

Naotaifang formula attenuates OGD/R-induced inflammation and ferroptosis by regulating microglial M1/M2 polarization through BMP6/SMADs signaling pathway
CONCLUSION: Microglial M1/M2 polarization plays a pivotal role in inflammation and ferroptosis during OGD/R. The BMP6/SMADs signaling pathway is a potential therapeutical target of inflammation and ferroptosis induced by the transformation of microglia. Moreover, NTF could alleviate inflammation and ferroptosis through the BMP6/SMADs signaling pathway in OGD/R-injured microglia.PMID:37713988 | DOI:10.1016/j.biopha.2023.115465
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 15, 2023 Category: Drugs & Pharmacology Authors: Jun Liao Mengzhen Wei Jianjun Wang Jinsong Zeng Danhong Liu Qiusi Du Jinwen Ge Zhigang Mei Source Type: research

Effectiveness and safety of oral anticoagulants for non-valvular atrial fibrillation: a population-based cohort study in primary healthcare in Catalonia
Conclusion: Being men, a previous event and DOAC-switch posed a higher risk for all study outcomes. direct oral anticoagulants had a protective effect against cerebral bleeding in comparison to vitamin K antagonists. Adherence to direct oral anticoagulants resulted in lower risk of stroke and cerebral bleeding. We found no differences in the risk of stroke and gastrointestinal bleeding when we compared direct oral anticoagulants vs. vitamin K antagonists.
Source: Frontiers in Pharmacology - September 15, 2023 Category: Drugs & Pharmacology Source Type: research

Assessment of Complex Flow Patterns in Patients With Carotid Webs, Patients With Carotid Atherosclerosis, and Healthy Subjects Using 4D Flow MRI
CONCLUSION: Lower TAWSS and higher OSI are present in the ICA bulb in patients with CaW when compared to patients with atherosclerotic or healthy subjects.EVIDENCE LEVEL: 2 TECHNICAL EFFICACY: Stage 2.PMID:37706274 | DOI:10.1002/jmri.29013
Source: Atherosclerosis - September 14, 2023 Category: Cardiology Authors: Retta El Sayed Charlie C Park Zahraw Shah Fadi B Nahab Diogo C Haussen Jason W Allen John N Oshinski Source Type: research

Aggressive LDL-C Lowering and the Brain: Impact on Risk for Dementia and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association
The objective of this scientific statement is to evaluate contemporary evidence that either supports or refutes the conclusion that aggressive low-density lipoprotein cholesterol lowering or lipid lowering exerts toxic effects on the brain, leading to cognitive impairment or dementia or hemorrhagic stroke. The writing group used literature reviews, references to published clinical and epidemiology studies, clinical and public health guidelines, authoritative statements, and expert opinion to summarize existing evidence and to identify gaps in current knowledge. Although some retrospective, case control, and prospective lon...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - September 14, 2023 Category: Cardiology Authors: Larry B Goldstein Peter P Toth Jennifer L Dearborn-Tomazos Robert P Giugliano Benjamin J Hirsh Jessica M Pe ña Magdy H Selim Daniel Woo American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular and Source Type: research

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