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Gastrointestinal bleeding in patients on novel oral anticoagulants: Risk, prevention and management.
Abstract Novel oral anticoagulants (NOACs), which include direct thrombin inhibitor (dabigatran) and direct factor Xa inhibitors (rivaroxaban, apixaban and edoxaban), are gaining popularity in the prevention of embolic stroke in non-valvular atrial fibrillation as well as in the prevention and treatment of venous thromboembolism. However, similar to traditional anticoagulants, NOACs have the side effects of bleeding, including gastrointestinal bleeding (GIB). Results from both randomized clinical trials and observations studies suggest that high-dose dabigatran (150 mg b.i.d), rivaroxaban and high-dose edoxaban (6...
Source: World Journal of Gastroenterology : WJG - March 21, 2017 Category: Gastroenterology Authors: Cheung KS, Leung WK Tags: World J Gastroenterol Source Type: research

Helicobacter Pylori Infection and Risk of Death From Cardiovascular Disease Among the Japanese Population: a Nested Case-Control Study within the JACC Study.
CONCLUSION: The results of this nested case-control study suggest that there is no association between H. pylori infection and CHD and stroke mortality risk in otherwise healthy, elderly Japanese individuals. PMID: 26084791 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - June 20, 2015 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Anticardiolipin Antibodies in Children with Helicobacter pylori Infection
ConclusionsIn our particular experience, H. pylori can cause aCL antibody positivity in children and eradication of H. pylori provides the disappearance of these antibodies.
Source: Helicobacter - April 1, 2015 Category: Gastroenterology Authors: Serdar Umit Sarıcı, Orhan Gursel, Emin Kurekci, Vural Kesik, Avni Atay, Vedat Okutan, Ali Inal, Aysel Pekel, Mehmet Ali Ozguven, Okan Ozcan Tags: Original Article Source Type: research