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Condition: Thrombosis
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Total 45 results found since Jan 2013.

Position statement from the Indian Society of Gastroenterology, Cardiological Society of India, Indian Academy of Neurology and Vascular Society of India on gastrointestinal bleeding and endoscopic procedures in patients on antiplatelet and/or anticoagulant therapy
AbstractAntiplatelet and/or anticoagulant agents (collectively known as antithrombotic agents) are used to reduce the risk of thromboembolic events in patients with conditions such as atrial fibrillation, acute coronary syndrome, recurrent stroke prevention, deep vein thrombosis, hypercoagulable states and endoprostheses. Antithrombotic-associated gastrointestinal (GI) bleeding is an increasing burden due to the growing population of advanced age with multiple comorbidities and the expanding indications for the use of antiplatelet agents and anticoagulants. GI bleeding in antithrombotic users is associated with an increase...
Source: Indian Journal of Gastroenterology - June 5, 2023 Category: Gastroenterology Source Type: research

Biosimilar tenecteplase versus alteplase in acute ischemic stroke: A real world study
Conclusion: This present study observed no difference in the efficacy and safety between biosimilar TNK and rTPA. Our findings are in concordance with published trials showing equivalence between the two molecules.
Source: Annals of Indian Academy of Neurology - January 25, 2023 Category: Neurology Authors: Ayush Mohan Snigdha Komakula Suhas Murali Pooja Anand Dyuti Shah VY Vishnu Awadh Kishor Pandit Ayush Agarwal Deepti Vibha Mamta Bhushan Singh MV Padma Srivastava Rohit Bhatia Source Type: research

Gut microbiota dysbiosis in patients with intracranial sino-venous thrombosis and acute ischemic stroke in the young
Varsha A Prabhu, Vinay Rajput, Rakeshkumar Yadav, Kushal Gohil, Mahesh S Dharne, Mazhuvancherry Kesavan Unnikrishnan, Sankar Prasad GorthiAnnals of Indian Academy of Neurology 2022 25(5):980-983
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Varsha A Prabhu Vinay Rajput Rakeshkumar Yadav Kushal Gohil Mahesh S Dharne Mazhuvancherry Kesavan Unnikrishnan Sankar Prasad Gorthi Source Type: research

Propensity of stroke in standard versus various aortic arch variants: A 200 patients study
Conclusions: Standard aortic arch Type 2, bovine aortic arch Type A, and Type B are associated with an early age at stroke presentation. During routine carotid evaluation by CT or MR angiography in stroke patients, it would be better to evaluate the aortic arch as well, especially in young patients.
Source: Annals of Indian Academy of Neurology - September 9, 2022 Category: Neurology Authors: Swapnil Samadhiya Vijay Sardana Bharat Bhushan Dilip Maheshwari Seeta Ram Yadav Ravi Goyal Source Type: research

Comparison of Extramedullary and Intramedullary Implants for Stable Intertrochanteric Fractures: Have We Swung the Pendulum Too Far the Other Way?
DISCUSSION: Our study found that extramedullary implants were associated with lower transfusions rates, lower readmissions, and better patient disposition. We recommend surgeons to consider extramedullary implants when treating stable IT fractures, especially if the patient is anemic or at high risk for hospital readmission.LEVEL OF EVIDENCE: Level III. Retrospective cohort study.PMID:35196299 | DOI:10.5435/JAAOS-D-21-00657
Source: The Journal of the American Academy of Orthopaedic Surgeons - February 23, 2022 Category: Orthopaedics Authors: Aria Darius Darbandi Ghulam H Saadat Ahmed Siddiqi Bennet A Butler Source Type: research

Acute ischemic stroke in children & #8211; should we thrombolyze ?
KP Vinayan, Vivek Nambiar, Vaishakh AnandAnnals of Indian Academy of Neurology 2022 25(1):21-25 Ischemic stroke is a major cause of acute neurological symptoms in children with significant long-term neurological sequelae. Unlike in the adult population, the clinical presentation of strokes in children may not be stereotyped. Hence, many other differential diagnostic possibilities might have to be considered in the emergency setting. Due to this heterogeneous presentation and the resultant clinical dilemma in the early detection, acute thrombolysis even now remains as a very rarely tried therapeutic option in children. Man...
Source: Annals of Indian Academy of Neurology - February 22, 2022 Category: Neurology Authors: KP Vinayan Vivek Nambiar Vaishakh Anand Source Type: research

Postoperative Complications in Patients With Hereditary Hemochromatosis Undergoing Total Joint Arthroplasty: A Matched Cohort Analysis
This study addresses a paucity in the current literature concerning the complication profile in HH patients with destructive joint arthropathy undergoing joint arthroplasty surgery.PMID:34932508 | DOI:10.5435/JAAOS-D-21-00105
Source: The Journal of the American Academy of Orthopaedic Surgeons - December 21, 2021 Category: Orthopaedics Authors: Amil R Agarwal Kevin Y Wang Amy L Xu Matthew J Best Varun Puvanesarajah Umasuthan Srikumaran Gregory J Golladay Savya C Thakkar Source Type: research

28675 A case of systemic amyloidosis diagnosed by dermatologic consult
A 49-year-old male with PMH of hypertension and diabetes was admitted to the neurology ICU following thrombolytic therapy for left MCA occlusive thrombus. Dermatology was consulted for desquamation of the lower lip, lateral tongue, and bruising of the eyelid and cheeks. Patient originally presented to outside hospital with bilateral lower extremity swelling and shortness of breath. BNP and troponins were elevated, and ACS protocol was initiated. He had stroke-like symptoms while at the outside facility and CT showed MCA occlusive thrombus.
Source: Journal of the American Academy of Dermatology - August 8, 2021 Category: Dermatology Authors: Alison Huber, Dr. Emily Smith Source Type: research

Predisposing factors and management of hemodynamic depression following carotid artery stenting
Pachipala Sudheer, Ayush Agarwal, Venugopalan Y Vishnu, MV Padma SrivastavaAnnals of Indian Academy of Neurology 2021 24(3):315-318 Carotid artery stenting (CAS) involves dilatation of carotid bulb which can trigger a series of neuronal responses resulting in hemodynamic depression that might influence the outcome of the procedure. This is a frequent but underdiagnosed complication of CAS. Although it is mild, transient and self-limiting in majority of cases, it can result in significant morbidity and mortality if persistent. Neurologists should be aware of the predisposing factors and management of this common complicati...
Source: Annals of Indian Academy of Neurology - July 17, 2021 Category: Neurology Authors: Pachipala Sudheer Ayush Agarwal Venugopalan Y Vishnu MV Padma Srivastava Source Type: research

Selective hand motor cortex lesions masquerading as & #8220;Pseudoperipheral Nerve Palsy & #8221;
Bhaskara P Shelley, Prakash Harishchandra, Acharya K DevadasAnnals of Indian Academy of Neurology 2020 23(5):688-693 Strategic cortical lesions involving the hand motor cortex (HMC) presenting acutely as distal upper limb pure motor weakness certainly do need to be differentiated on clinical grounds from “pseudoperipheral palsy.” This rare phenotype can imitate peripheral motor nerve deficits and should not be easily overlooked. The? isolated “central hand and finger weakness” presenting as an acute onset of varying combinations such as pseudomedian, pseudoradial,...
Source: Annals of Indian Academy of Neurology - December 8, 2020 Category: Neurology Authors: Bhaskara P Shelley Prakash Harishchandra Acharya K Devadas Source Type: research

Depression and quality of life after cerebral venous sinus thrombosis
Conclusion: This is the first Indian study demonstrating depression in patients with CVST and use of SA-SIP to assess quality of life in them. Occurrence of depression in CVST is as high as in arterial strokes.
Source: Annals of Indian Academy of Neurology - August 20, 2020 Category: Neurology Authors: Aralikatte O Saroja Ninad N Thorat Karkal R Naik Source Type: research

Mortality and Morbidity of Surgical Management of Geriatric Ankle Fractures.
DISCUSSION: After controlling for comorbidities (ie, the ASA class), no increased risk is observed for the 30-day mortality or complication rate between geriatric ankle fracture in the 65 to 79 years old and the 80 to 99 years old age groups. LEVEL OF EVIDENCE: Prognostic level III, retrospective study. PMID: 32769723 [PubMed - in process]
Source: The Journal of the American Academy of Orthopaedic Surgeons - August 13, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Protease-independent action of tissue plasminogen activator in brain plasticity and neurological recovery after ischemic stroke Neuroscience
In this study, we investigated the role of tPA on primary neurons in culture and on brain recovery and plasticity after ischemic...
Source: Proceedings of the National Academy of Sciences - April 29, 2019 Category: Science Authors: Hongjian Pu, Yejie Shi, Lili Zhang, Zhengyu Lu, Qing Ye, Rehana K. Leak, Fei Xu, Shubei Ma, Hongfeng Mu, Zhishuo Wei, Na Xu, Yuguo Xia, Xiaoming Hu, T. Kevin Hitchens, Michael V. L. Bennett, Jun Chen Tags: PNAS Plus Source Type: research