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Condition: ALS
Management: National Institutes of Health (NIH)

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Total 7 results found since Jan 2013.

Long Covid is a ‘national crisis.’ So why are grants taking so long to get?
Some content has been removed for formatting reasons. Please view the original article for the best reading experience. David Putrino, a neurophysiologist at the Icahn School of Medicine at Mount Sinai, labored through his holiday last Christmas to write a grant application for urgently needed Long Covid research. With colleagues, he hoped to tap into $1.15 billion in funding that Congress granted the National Institutes of Health (NIH) in 2020, as Long Covid emerged as a major public health problem. NIH had solicited grant applications in December 2021, just weeks before their January due date. The agency said it pla...
Source: Science of Aging Knowledge Environment - June 10, 2022 Category: Geriatrics Source Type: research

Scientists discover a new genetic form of ALS in children
(NIH/National Institute of Neurological Disorders and Stroke) In a study of 11 medical-mystery patients, an international team of researchers led by scientists at the National Institutes of Health and the Uniformed Services University (USU) discovered a new and unique form of amyotrophic lateral sclerosis (ALS). Unlike most cases of ALS, the disease began attacking these patients during childhood, worsened more slowly than usual, and was linked to a gene, called SPTLC1, that is part of the body's fat production system.
Source: EurekAlert! - Medicine and Health - May 31, 2021 Category: International Medicine & Public Health Source Type: news

NIH researchers link cases of ALS and FTD to a Huntington's disease-associated mutation
(NIH/National Institute of Neurological Disorders and Stroke) A study led by researchers at the National Institutes of Health has made a surprising connection between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two disorders of the nervous system, and the genetic mutation normally understood to cause Huntington's disease. This large, international project, which included a collaboration between the National Institute of Neurological Disorders and Stroke (NINDS) and the National Institute on Aging (NIA), opens a potentially new avenue for diagnosing and treating some individuals with FTD or ALS.
Source: EurekAlert! - Medicine and Health - December 4, 2020 Category: International Medicine & Public Health Source Type: news

Scripps Florida scientist and collaborators win $7 million grant to develop new ALS treatments
(Scripps Research Institute) Professor Matthew Disney of the Department of Chemistry on the Florida campus of The Scripps Research Institute (TSRI), together with scientists from Mayo Clinic's Florida campus and Johns Hopkins School of Medicine, has been awarded $7.2 million from the National Institute of Neurological Disorders and Stroke of The National Institutes of Health to create new RNA-based treatments for the most common form of amyotrophic lateral sclerosis (ALS), as well as a type of frontotemporal dementia (FTD).
Source: EurekAlert! - Medicine and Health - June 15, 2017 Category: International Medicine & Public Health Source Type: news

Scientists discover urinary biomarker that may help track ALS
(NIH/National Institute of Neurological Disorders and Stroke) A study in Neurology suggests that analyzing levels of the protein p75ECD in urine samples from people with amyotrophic lateral sclerosis (ALS) may help monitor disease progression as well as determine the effectiveness of therapies. The study was supported by National Institute of Neurological Disorders and Stroke (NINDS) and National Center for Advancing Translational Sciences (NCATS), both part of the National Institutes of Health.
Source: EurekAlert! - Biology - March 22, 2017 Category: Biology Source Type: news

Nuclear transport problems linked to ALS and FTD
Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell’s nucleus, or command center where most of its DNA is stored.
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - October 16, 2015 Category: Neurology Source Type: news

Dormant viral genes may awaken to cause ALS
Scientists at the National Institutes of Health (NIH) discovered that reactivation of ancient viral genes embedded in the human genome may cause the destruction of neurons in some forms of amyotrophic lateral sclerosis (ALS).
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - September 30, 2015 Category: Neurology Source Type: news