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Platypnoea orthodeoxia syndrome and its association with cryptogenic ischaemic stroke
J R Coll Physicians Edinb. 2023 Mar 4:14782715231159470. doi: 10.1177/14782715231159470. Online ahead of print.ABSTRACTPlatypnoea orthodeoxia syndrome is a rare condition, which can be present in patients with patent foramen ovale (PFO). In this case, a 72-year-old lady presented to the emergency department with a cryptogenic stroke associated with right thalamic infarct. While in hospital, it was noticed that the patient had desaturations in the upright position, and these improved in the recumbent position, consistent with platypnoea orthodeoxia syndrome. The patient was found to have a PFO, which was then closed, and he...
Source: Journal of the Royal College of Physicians of Edinburgh - March 4, 2023 Category: General Medicine Authors: Abdul Salam Snigdhendu Mandal Samaah Fathima Sripriya Rasthapuram Krishnakumar Radhakrishnan Source Type: research

Echocardiographic Measures of Left Atrial Function and Size and Incident Dementia
To the Editor A recent study described a significant association between left atrial function and an increased risk of subsequent dementia, independent of the presence of atrial fibrillation. These findings are similar to our 2009 study, which examined subclinical left atrial dysfunction and risk of stroke in patients with patent foramen ovale (PFO). We found that impairment of reservoir, conduit, and contractile strain and impairment of emptying, passive emptying, and active emptying fraction was present in patients with multiple ischemic events, PFO, and atrial septal aneurysm compared with healthy individuals. After PFO...
Source: JAMA - July 19, 2022 Category: General Medicine Source Type: research

Transcatheter device closure of postmyocardial infarction ventricular septal defect
Conclusion Our findings indicate that transcatheter device closure of PMIVSD is technically feasible, safe, and effective to reduce the shunt. The crucial prognostic factors were ascertained to be age ≥ 80 years, systolic blood pressure ≤ 90 mmHg, and procedure time ≥180 minutes.
Source: Journal of the Chinese Medical Association - November 22, 2016 Category: Journals (General) Source Type: research

Cardiovascular diseases in patients 65 years and younger with non-cardiogenic stroke.
CONCLUSIONS: Aetiologically heterogeneous stroke and cardiogenic stroke are the most commonly observed among young stroke patients. Cardiomyopathy and atrial fibrillation are the most common sources of cerebral embolism in young patients with cardiogenic stroke. Nearly 1/5 of patients with a non-cardiogenic stroke have congenital or acquired structural changes in the heart. PMID: 27279848 [PubMed]
Source: Archives of Medical Science - June 10, 2016 Category: Journals (General) Tags: Arch Med Sci Source Type: research