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Paradoxical venous air embolism detected with point-of-care ultrasound: a case report
We present a case of a critical care patient who presented sudden clinical hemodynamic deterioration after the removal of central venous catheter. Hemodynamic evaluation with point-of-care ultrasound (POCUS) showed bubbles in both right and left heart cavities wherewith air embolism facilitated by heart septal defect was suspected. Therefore, the patient was reintubated, supported with vasopressors and a new CVC was inserted to proceed with air aspiration. Shortly after, the patient ’s hemodynamic status improved in terms of vital signs stabilization. 6 h after the event with optimal perfusion markers and diminished sed...
Source: Critical Ultrasound Journal - May 18, 2022 Category: Radiology Source Type: research

Improved detection of coarctation of the aorta using speckle tracking analysis of the fetal heart using the last examination prior to delivery.
CONCLUSIONS: Speckle tracking analysis of multiple ventricular measurements may be helpful to separate fetuses that are suspected to have CoA prenatally from those who do not. This article is protected by copyright. All rights reserved. PMID: 32022339 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - February 4, 2020 Category: Radiology Authors: DeVore GR, Haxel C, Satou G, Sklansky M, Pelka MJ, Jone PN, Cuneo BF Tags: Ultrasound Obstet Gynecol Source Type: research

Human Fetal Hearts with Tetralogy of Fallot have Altered Fluid Dynamics and Forces.
In this study, we performed patient-specific ultrasound-based flow simulations of 3 TOF and 7 normal human fetal hearts. TOF right ventricles (RV) had smaller end-diastolic volumes (EDV) but similar stroke volumes (SV), while TOF left ventricles (LV) had similar EDV but slightly increased SV compared to normal ventricles. Simulation showed that TOF ventricles had elevated systolic intra-ventricular pressure gradient (IVPG), and required additional energy for ejection, but IVPG elevations were considered to be mild relative to arterial pressure. TOF RV and LV had similar pressures due to equalization via ventricular septal ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - September 14, 2018 Category: Physiology Authors: Wiputra H, Chen CK, Talbi E, Lim GL, Soomar SM, Biswas A, Mattar CNZ, Bark D, Leo HL, Yap CH Tags: Am J Physiol Heart Circ Physiol Source Type: research

Recent Nationwide Trends in Transcranial Doppler Utilization During Acute Ischemic Stroke Hospitalizations (P4.296)
Conclusions:Over the last decade there has been a slight but steady decrease in the use of TCD during AIS hospitalizations in the US. Future studies should examine the cost-utility of TCD, especially with the advent of endovascular stroke treatment systems.Disclosure: Dr. Liu has nothing to disclose. Dr. Lunagariya has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Feng has nothing to disclose. Dr. Ovbiagele has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Liu, Y., Lunagariya, A., Patel, U., Patel, A., Feng, W., Ovbiagele, B. Tags: In-Hospital Stroke Care Source Type: research

Cardiovascular diseases in patients 65 years and younger with non-cardiogenic stroke.
CONCLUSIONS: Aetiologically heterogeneous stroke and cardiogenic stroke are the most commonly observed among young stroke patients. Cardiomyopathy and atrial fibrillation are the most common sources of cerebral embolism in young patients with cardiogenic stroke. Nearly 1/5 of patients with a non-cardiogenic stroke have congenital or acquired structural changes in the heart. PMID: 27279848 [PubMed]
Source: Archives of Medical Science - June 10, 2016 Category: Journals (General) Tags: Arch Med Sci Source Type: research

Atrial Septal Defects and Cardioembolic Strokes
Atrial septal defects (ASDs) can be complicated by cardioembolic strokes, but the exact incidence is unknown. Patients with large and small shunts may present with a cardioembolic stroke. Patients with cryptogenic strokes should have cardiac ultrasound to see if an ASD is present. Cardioembolic strokes associated with ASD principally occur with 2 mechanisms. The first is paradoxic embolism involving a venous-based source of thrombus, which may subsequently pass through the ASD by right-to-left shunting, causing a cardioembolic stroke. The second is atrial fibrillation that can complicate the course of patients with ASDs, e...
Source: Cardiology Clinics - March 9, 2016 Category: Cardiology Authors: Michelle Leppert, Sharon N. Poisson, John D. Carroll Source Type: research

Quantification of Shunt Volume Through Ventricular Septal Defect by Real-Time 3-D Color Doppler Echocardiography: An Study
Quantification of shunt volume is important for ventricular septal defects (VSDs). The aim of the in vitro study described here was to test the feasibility of using real-time 3-D color Doppler echocardiography (RT3-D-CDE) to quantify shunt volume through a modeled VSD. Eight porcine heart phantoms with VSDs ranging in diameter from 3 to 25 mm were studied. Each phantom was passively driven at five different stroke volumes from 30 to 70 mL and two stroke rates, 60 and 120 strokes/min. RT3-D-CDE full volumes were obtained at color Doppler volume rates of 15, 20 and 27 volumes/s.
Source: Ultrasound in Medicine and Biology - February 2, 2016 Category: Radiology Authors: Meihua Zhu, Muhammad Ashraf, Lydia Tam, Cole Streiff, Sumito Kimura, Eriko Shimada, David J. Sahn Tags: Original Contribution Source Type: research

Medtech approvals: FDA releases August 2015 PMAs
The FDA today released its list of the pre-market approvals it granted for medical devices in August 2015: Summary of PMA Originals & Supplements Approved Originals: 2 Supplements: 70 Summary of PMA Originals Under Review Total Under Review: 57 Total Active: 28 Total On Hold: 29 Summary of PMA Supplements Under Review Total Under Review: 569 Total Active: 422 Total On Hold: 147 Summary of All PMA Submissions Originals: 5 Supplements: 90 Summary of PMA Supplement PMA Approval/Denial Decision Times Number of Approvals: 70 Number of Denials: 0 Average Days Fr Receipt to Decision (Total Time): 229.0 FDA Time: 130...
Source: Mass Device - October 23, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Food & Drug Administration (FDA) Pre-Market Approval (PMA) Regulatory/Compliance Source Type: news

Correlation of Atrial Septal Defect Size as Measured by Intracardiac Echocardiography and Transcranial Doppler Ultrasound in Children and Young Adults (P02.102)
CONCLUSIONS: Curtain result on TCD bubble studies is associated with significantly larger ASDs and other cardiac abnormalities in children and young adults.Disclosure: Dr. Doan has nothing to disclose. Dr. Barreto has nothing to disclose. Dr. Fulep has nothing to disclose. Dr. Bui has nothing to disclose. Dr. Butler has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Doan, D., Barreto, A., Fulep, E., Bui, T.-T., Butler, I. Tags: P02 Child Neurology I Source Type: research