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Stroke Prevention After Cryptogenic Stroke
AbstractPurpose of ReviewCryptogenic stroke represents a heterogenous but clinically important collection of stroke etiologies for which our understanding continues to grow. Here, we review our current knowledge and most recent recommendations on secondary prevention for common causes of cryptogenic stroke including paroxysmal atrial fibrillation, atrial cardiopathy, patent foramen ovale, and substenotic atherosclerotic disease as well as the under-recognized mechanisms of occult malignancy, heart failure, and, most recently, infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).Recent FindingsThe res...
Source: Current Cardiology Reports - October 16, 2021 Category: Cardiology Source Type: research

Patent Foramen Ovale related cryptogenic stroke during COVID-19 disease in three patients: a case series
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), termed COVID-19, first detected in Whuan, was officially declared a pandemic by the World Health Organization on March 11, 2020. The epidemic of COVID-19 has rapidly spread worldwide. Italy was the first European country to be affected and, currently, Italy has reported 4,343,397 COVID-19-positive cases (1).
Source: Journal of Stroke and Cerebrovascular Diseases - September 13, 2021 Category: Neurology Authors: Daniela Palleri, Marta Guidarini, Elisabetta Mariucci, Anna Balducci, Gabriele Egidy Assenza, Susanna Esposito, Andrea Donti Source Type: research

Unexplained arterial thrombosis: approach to diagnosis and treatment
We present a structured approach to diagnosis with consideration of common causes, including atherosclerosis and embolism, as well as uncommon causes, including medications and substances, vascular and anatomic abnormalities, systemic disorders, and thrombophilias. We highlight areas of management that have evolved within the past 5 years, including the use of dual-pathway inhibition in atherosclerotic disease, antithrombotic therapy selection in embolic stroke of undetermined source and left ventricular thrombus, the role of closure of patent foramen ovale for secondary stroke prevention, and the thrombotic potential of c...
Source: Atherosclerosis - December 10, 2021 Category: Cardiology Authors: Jori E May Stephan Moll Source Type: research