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Patent foramen ovale closure following cryptogenic stroke or transient ischaemic attack: Long‐term follow‐up of 301 cases
Patent foramen ovale has been identified as a conduit for paradoxical embolism resulting in cryptogenic stroke or transient ischemic attack (TIA). We aimed to establish rates of death, recurrent stroke or TIA among patients undergoing PFO closure for stroke or TIA at our unit. A retrospective analysis of all PFO closure patients was performed between May 2004 and January 2013. Follow up was performed by mortality tracing using the Medical Research Information Service of the Office of National Statistics. With regard to stroke or TIA recurrence, written consent forms and questionnaires were mailed with follow up telephone c...
Source: Catheterization and Cardiovascular Interventions - June 23, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Mikaeil Mirzaali, Maureen Dooley, Dylan Wynne, Nina Cooter, Lorraine Lee, Peter Haworth, Romi Saha, Nicola Gainsborough, David Hildick‐Smith Tags: Valvular and Structural Heart Diseases Source Type: research

Transcatheter closure of patent foramen ovale for secondary prevention of ischemic stroke: Quantitative synthesis of pooled randomized trial data
ConclusionsBased on the results of this analysis of randomized trial data, percutaneous PFO closure appears to be a safe and effective therapeutic option for the secondary prevention of ischemic stroke in patients with PFO and cryptogenic stroke.
Source: Catheterization and Cardiovascular Interventions - January 14, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Abdul Hakeem, Mehmet Cilingiroglu, Angelos Katramados, Konstantinos Dean Boudoulas, Cezar Iliescu, Betul Gundogdu, Konstantinos Marmagkiolis Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

Management of patients with patent foramen ovale and cryptogenic stroke
Conclusions: Available data provided the basis for a shared approach to management of cryptogenic ischemic cerebral events and PFO among different Italian scientific societies. Wider international initiatives on the topic are awaited. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - June 21, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Christian Pristipino, Gian Paolo Anzola, Luigi Ballerini, Antonio Bartorelli, Moreno Cecconi, Massimo Chessa, Andrea Donti, Achille Gaspardone, Giuseppe Neri, Eustaquio Onorato, Gualtiero Palareti, Serena Rakar, Gianluca Rigatelli, Gennaro Santoro, Danilo Tags: Pediatric and Congenital Heart Disease Source Type: research

Initial experience with the novel patent foramen ovale occlusion device Nit‐Occlud® PFO in patients with stroke or transient ischemic attack
Conclusion: In patients with cryptogenic stroke or transient ischemic attack and a PFO, the Nit‐Occlud® PFO Occlusion Device appears to be both a safe and effective means to occlude the PFO. It is associated with high procedural success and favorable rates of complete closure. © 2014 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - June 19, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Daniel H Steinberg, Stefan C Bertog, Julia Momberger, Jennifer Franke, Ilona Hofmann, Kristina Renkhoff, Sonya Joy, Laura Vascelyte, Horst Sievert Tags: Original Studies Source Type: research

Initial experience with the novel patent foramen ovale occlusion device Nit‐Occlud® in patients with stroke or transient ischemic attack
ConclusionIn patients with cryptogenic stroke or TIA and a PFO, the Nit‐Occlud® PFO Occlusion Device appears to be both a safe and effective means to occlude the PFO. It is associated with high procedural success and favorable rates of complete closure. © 2015 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - April 2, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Daniel H. Steinberg, Stefan C. Bertog, Julia Momberger, Jennifer Franke, Ilona Hofmann, Kristina Renkhoff, Sonya Joy, Laura Vaskelyte, Horst Sievert Tags: Valvular and Structural Heart Diseases Source Type: research

Embolic stroke of undetermined source and patent foramen ovale closure: Practice insights from meta ‐analysis?
Key Points Closure of patent foramen ovale (PFO) in embolic stroke of undetermined source (ESUS) reduces recurrent stroke compared with antiplatelet therapy in select patients but increases risk of atrial fibrillation. Device closure is an attractive option for young patients with an anatomically higher risk PFO and imaging proven ESUS. Benefit of PFO closure in ESUS compared with oral anticoagulation remains undefined.
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Arka Chatterjee, William B. Hillegass Tags: Valvular and Structural Heart Diseases Source Type: research

Percutaneous PFO closure for paradoxical stroke in 8‐kg twins
We present two cases of PFO closures in identical 8 kg twin boys with Hurler’s syndrome who had central lines for planned bone marrow transplants, with embolic stroke in one. We discuss the treatment options as well as the special challenges based on the patients’ age, size, and diagnoses. We also discuss the technical aspects and safety of percutaneous PFO closure. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - September 1, 2013 Category: Cardiovascular & Thoracic Surgery Authors: James Hill, Tamar Preminger Tags: Case Report Source Type: research

Long‐term follow‐up after PFO device closure
ConclusionsDevice closure of PFO can be performed safely with very good long‐term resolution of atrial shunting. Recurrent neurologic events after PFO closure may reflect additional comorbid risk factors unrelated to the potential for paradoxical embolism. © 2016 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - March 28, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Nathaniel W. Taggart, Guy S. Reeder, Ryan J. Lennon, Joshua P. Slusser, Monique A. Freund, Allison K. Cabalka, Frank Cetta, Donald J. Hagler Tags: Valvular and Structural Heart Diseases Source Type: research

Long ‐term follow‐up after PFO device closure
ConclusionsDevice closure of PFO can be performed safely with very good long‐term resolution of atrial shunting. Recurrent neurologic events after PFO closure may reflect additional comorbid risk factors unrelated to the potential for paradoxical embolism. © 2016 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - March 28, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Nathaniel W. Taggart, Guy S. Reeder, Ryan J. Lennon, Joshua P. Slusser, Monique A. Freund, Allison K. Cabalka, Frank Cetta, Donald J. Hagler Tags: Valvular and Structural Heart Diseases Source Type: research

Percutaneous patent foramen ovale closure using the Occlutech Figulla device: More than 1,300 patient ‐years of follow up
ConclusionThe Occlutech device appears to be safe at long ‐term FU with a very low annual cerebrovascular event rate and a low moderate to large shunt rate at 1‐year FU.
Source: Catheterization and Cardiovascular Interventions - November 20, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Roel J. R. Snijder, Laura E. Renes, Maarten Jan Suttorp, Jurrien M. ten Berg, Martijn C. Post Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

Interventional closure of patent foramen ovale with Nit ‐occlud® device in prevention of recurrent neurologic events—Long‐term results
ConclusionsThe Nit‐Occlud PFO device and its delivery system are safe and provides sufficient closure of PFO in patients who suffered from cryptogenic stroke, TIA or paradoxical peripheral embolism. It is associated with high procedural success and favorable rates of complete closure.
Source: Catheterization and Cardiovascular Interventions - October 25, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Aleksander Araszkiewicz, Sylwia S ławek, Olga Trojnarska, Maciej Lesiak, Marek Grygier Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

A meta‐analysis of transcatheter closure of patent foramen ovale versus medical therapy for prevention of recurrent thromboembolic events in patients with cryptogenic cerebrovascular events
ConclusionIn this meta‐analysis of contemporary RCTs, successful transcatheter closure of PFO might be more effective than medical therapy alone for the prevention of recurrent thromboembolic events. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - July 5, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Andrés M. Pineda, Francisco O. Nascimento, Solomon Yang, Ajay Kirtane, Robert Sommer, Nirat Beohar Tags: Original Studies Source Type: research

Results of percutaneous closure of patent foramen ovale with the GORE ® Septal Occluder
Conclusion. PFO closure with the GSO is accompanied by a high technical success rate and closure rates similar to other currently used devices. The incidence of atrial fibrillation was higher than reported with most other devices. This may be a chance finding but warrants further investigation in larger trials. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - December 10, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Meike Knerr, Stefan Bertog, Laura Vaskelyte, Ilona Hofmann, Horst Sievert Tags: Original Study Source Type: research

Results of percutaneous closure of patent foramen ovale with the GORE® septal occluder
ConclusionPFO closure with the GSO is accompanied by a high technical success rate and closure rates similar to other currently used devices. The incidence of AF was higher than reported with most other devices. This may be a chance finding but warrants further investigation in larger trials. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - January 20, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Meike Knerr, Stefan Bertog, Laura Vaskelyte, Ilona Hofmann, Horst Sievert Tags: Valvular and Structural Heart Diseases Source Type: research

PFO closure: End of an era or beginning of a new chapter?
Key Points This large long‐term retrospective cohort study shows that percutaneous patent foramen ovale (PFO) closure is safe. Higher rates of recurrent stroke or TIA were noted in older patients (age>55) and those with diabetes and hypertension Randomized trials have failed to show significant benefit from PFO closure for cryptogenic stroke though pooled analyses and longer‐term follow‐up have revealed significant reduction in recurrent strokes. Future studies and longer‐term follow‐up will need to elucidate which subgroups of patients will benefit from closure.
Source: Catheterization and Cardiovascular Interventions - January 23, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Mahmoud I. Traina, E. Murat Tuzcu Tags: Editorial Comment Source Type: research

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